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Source: International Journal of Cardiology
Condition: Thrombosis
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Total 95 results found since Jan 2013.
Stroke and urosepsis after discontinuation of rivaroxaban
We report a patient with stroke shortly after discontinuation of rivaroxaban with a complicated course.
Source: International Journal of Cardiology - November 4, 2013 Category: Cardiology Authors: Claudia Stöllberger, Josef Finsterer Tags: Online Letters to the Editor Source Type: research
Isolated noncompaction of the left ventricular myocardium and intraventricular thrombosis detected by magnetic resonance imaging
A 67-year-old asymptomatic woman who had a history of suspect myocarditis at the age of 37 and a history of minor stroke two years ago, presented for a routinary evaluation. Physical examination revealed no abnormal findings. ECG showed sinus rhythm, left ventricular hypertrophy, and ST changes in anterior leads. Both treadmill exercise testing and 24-hour Holter monitoring excluded ventricular or supraventricular arrhythmias and a normal exercise capacity was assessed. Echocardiography demonstrated a thickened apex of the left ventricle, but was not able to distinguish between hypertrophy and noncompaction myocardium; the...
Source: International Journal of Cardiology - September 3, 2013 Category: Cardiology Authors: Giuseppe Molinari, Alberto Valbusa, Stefano Domenicucci Tags: Online Letters to the Editor Source Type: research
Clopidogrel is safer than ticagrelor in regard to bleeds: A closer look at the PLATO trial
Conclusions: Clopidogrel is safer than ticagrelor in regard to bleeding. Additionally, ticagrelor's purported faster antiplatelet ‘offset’ is substantially longer than its pharmacokinetics indicate. Considering the fact that the mortality, stent thrombosis and myocardial infarction ‘benefit’ of ticagrelor have recently been challenged, and that the increase in stroke on ticagrelor has recently been shown to be worse than originally published, the decision to use ticagrelor over clopidogrel in the face of a higher risk for bleeds is not advised.
Source: International Journal of Cardiology - July 31, 2013 Category: Cardiology Authors: James J. DiNicolantonio, Fabrizio D'Ascenzo, Ales Tomek, Saurav Chatterjee, Asfandyar K. Niazi, Giuseppe Biondi-Zoccai Tags: Editorials Source Type: research
Anticoagulation with a new oral anticoagulant in heart transplant recipients
Rivaroxaban is now accepted for prevention of stroke and systemic embolism in adult patients with non-valvular atrial fibrillation with one or more risk factors, and treatment and secondary prevention of deep vein thrombosis and pulmonary embolism. Nothing is known about the use of this new anticoagulant in transplanted patients. Here we report a series of heart transplant recipients treated with rivaroxaban and followed at our transplantation center.
Source: International Journal of Cardiology - July 25, 2013 Category: Cardiology Authors: Pierre Ambrosi, Bernard Kreitmann, William Cohen, Gilbert Habib, Pierre Morange Tags: Letters to the Editor Source Type: research
Early safety of the Amplatzer Cardiac Plug™ for left atrial appendage occlusion
Conclusions: In this single operator report, LAA occlusion using the double element ACP™ can be safely performed with excellent success rates. Using very specific deployment success, stability and release criteria, this device can achieve LAA occlusion with extremely low complication rates in an extremely frail oral anticoagulant ineligible population with multiple co-morbidities.
Source: International Journal of Cardiology - July 25, 2013 Category: Cardiology Authors: David Meerkin, Adi Butnaru, Dmitry Dratva, Olivier F. Bertrand, Dan Tzivoni Tags: Original Articles Source Type: research
Cholesterol-adjusted vitamin E serum levels are associated with cardiovascular events in patients with non-valvular atrial fibrillation
Abstract: Background: Non-valvular atrial fibrillation is associated with an increase in thromboembolism, i.e. stroke, and atherosclerotic events, i.e. myocardial infarction. Vitamin E possesses anti-coagulant as well as anti-atherosclerotic properties.Our aim was to assess whether vitamin E is associated with cardiovascular events in patients with non-valvular atrial fibrillation.Methods: Serum levels of cholesterol-adjusted vitamin E were measured in 1012 patients with non-valvular atrial fibrillation. Patients were followed for a mean time of 27.0months, and cardiovascular events, such as cardiovascular death and fatal ...
Source: International Journal of Cardiology - May 7, 2013 Category: Cardiology Authors: Roberto Cangemi, Pasquale Pignatelli, Roberto Carnevale, Gino Roberto Corazza, Daniele Pastori, Alessio Farcomeni, Stefania Basili, Giovanni Davì, Domenico Ferro, William R. Hiatt, Giuseppe Licata, Gregory Y.H. Lip, Lorenzo Loffredo, Pier Mannuccio Mannu Tags: Original Articles Source Type: research
Diagnostic value of portable electrocardiogram (Cardiophone) in patients complaining of palpitation
In this study, we retrospectively analyzed 6years of experience to determine the diagnostic value of Cardiophone.
Source: International Journal of Cardiology - May 6, 2013 Category: Cardiology Authors: Yoshiyasu Aizawa, Seiji Takatsuki, Yuko Suenaga, Takehiro Kimura, Nobuhiro Nishiyama, Kotaro Fukumoto, Yoko Tanimoto, Kojiro Tanimoto, Shun Kohsaka, Yukiko Fukuda, Mitsushige Murata, Shunichiro Miyoshi, Toshiaki Sato, Shiro Iwanaga, Satoshi Ogawa, Keiichi Tags: Letters to the Editor Source Type: research
Chronic renal disease is associated with stroke and thromboembolism in atrial fibrillation independently from gender
We have read with great interest the article by Guo and colleagues concerning renal dysfunction (defined as the presence of chronic dialysis, renal transplantation or an estimated glomerular filtration rate, eGFR,
Source: International Journal of Cardiology - May 3, 2013 Category: Cardiology Authors: Rui Providência, Sérgio Barra, Luís Paiva Tags: Letters to the Editor Source Type: research
Resistant to thrombosis, induced stroke and heart arrest by incorporation of a single gene of PGI2-synthesizing COX-1-PGIS in vivo: Implication against human heart disease
In prostanoid biosynthesis, upstream cyclooxygenases (COXs), including the house keeping COX isoform-1 (COX-1) and the inducible COX isoform-2 (COX-2), convert arachidonic acid (AA) into prostaglandin G2 (PGG2) by cyclooxygenase activity and then into prostaglandin H2 (PGH2) by peroxidase activity. PGH2 is not stable and quickly isomerized into different prostanoids, including thromboxane A2 (TXA2) by TXA2 synthase (TXAS), prostacyclin (PGI2) by PGI2 synthase (PGIS), or prostaglandin E2 (PGE2) by PGE2 synthase (PGES) respectively . TXA2 is a pro-platelet aggregator and vasoconstrictor. In contrast, PGI2 has opposite functi...
Source: International Journal of Cardiology - April 22, 2013 Category: Cardiology Authors: Ke-He Ruan, Anita J. Mohite, Shui-Ping So Tags: Letters to the Editor Source Type: research
Routine preprocedural transesophageal echocardiography might not be necessary for stroke prevention evaluation in AF patients on anticoagulation therapy
Conclusion: The overall periprocedural stroke rate was low (0.3%) in AF patients on anticoagulation therapy. The preprocedural MDCT detected all patients with the LA thrombus. In AF patients with low CHADS2 score, optimal anticoagulation and relatively preserved left ventricular ejection fraction, routine preprocedural TEE in addition to the MDCT might not be necessary to decrease the periprocedural stroke rate.
Source: International Journal of Cardiology - January 25, 2013 Category: Cardiology Authors: Jae-Hyun Han, Dong-Ho Shin, Hye-Jeong Lee, Young Jin Kim, Seung-Hyun Lee, Jaemin Shim, Jae-Sun Uhm, Jong-Youn Kim, Hyuk-Jae Chang, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung Tags: Original Articles Source Type: research
Validation of contemporary stroke and bleeding risk stratification scores in non-anticoagulated Chinese patients with atrial fibrillation
Abstract: Background: Risk stratification schemes assessing stroke and thromboembolism (stroke/TE) and bleeding relating to atrial fibrillation (AF) have largely been derived and validated in Western populations. We assessed risk factors that constitute scores for assessing stroke/TE (CHADS2, CHA2DS2-VASc) and bleeding (HAS-BLED), and the predictive value of these scores in a large cohort of Chinese patients with AF.Methods and results: We studied 1034 AF patients (27.1% female, median age 75; 85.6% non-anticoagulated) with mean follow-up of 1.9years. On multivariate analysis, vascular disease was independently associated ...
Source: International Journal of Cardiology - November 19, 2012 Category: Cardiology Authors: Yutao Guo, Stavros Apostolakis, Andrew D. Blann, Haijun Wang, Xiaoning Zhao, Yu Zhang, Dexian Zhang, Jingling Ma, Yutang Wang, Gregory Y.H. Lip Tags: Original Articles Source Type: research
Avicenna's view on the prevention of thrombosis
Thrombosis is defined as “hemostasis in the wrong place”. It makes a major contribution to mortality and morbidity in a wide range of patient populations. New or recurrent strokes affect about 795,000 people in the United States each year. In a third of patients, a complication of deep venous thrombosis is caused by embolisation of the clot into the lungs . After heart attack and stroke, pulmonary embolism takes the third rank as the most common cause of death from cardiovascular disease . Venous thrombosis is a common disease with frequent recurrences. Anticoagulants can prevent its recurrence, albeit at the cost of bleeding .
Source: International Journal of Cardiology - November 12, 2012 Category: Cardiology Authors: Ashraf Al-din Gooshah Gir, Hasan Namdar, Elham Emaratkar, Esmaeil Nazem, Mohammad Bagher Minaii, Ali reza Nikbakht Nasrabadi, Rasool Choopani Tags: Letters to the Editor Source Type: research
Stroke risk and suboptimal thromboprophylaxis in Chinese patients with atrial fibrillation: Would the novel oral anticoagulants have an impact?
Abstract: Background: The risk of stroke associated with atrial fibrillation (AF) is higher in Far Eastern population than in Western population, and warfarin use suboptimal. There is uncertainty whether the novel oral anticoagulants (NOACs) would have a major impact on stroke prevention in Far Eastern populations with AF.Objectives: We investigated current antithrombotic therapy use on stroke and bleeding risk, determinants of warfarin use and performed a modeling analysis of the net clinical benefit of the NOACs (apixaban, dabigatran) in a large cohort of Chinese patients with AF.Methods: We studied 1034 Chinese patients...
Source: International Journal of Cardiology - October 24, 2012 Category: Cardiology Authors: Yutao Guo, Ron Pisters, Stavros Apostolakis, Andrew D. Blann, Haijun Wang, Xiaoning Zhao, Yu Zhang, Dexian Zhang, Jingling Ma, Yutang Wang, Gregory Y.H. Lip Tags: Original Articles Source Type: research
Comparative assessment of published atrial fibrillation stroke risk stratification schemes for predicting stroke, in a non-atrial fibrillation population: The Chin-Shan Community Cohort Study
Conclusion: Contemporary stroke risk stratification schema used for AF can also be applied to non-AF populations with a similar (modest) predictive value. Given their simplicity (e.g. CHADS2 score), these scores could potentially be used for a ‘quick’ evaluation of stroke risk in non-AF populations, in a similar manner to AF populations.
Source: International Journal of Cardiology - October 16, 2012 Category: Cardiology Authors: Gregory Y.H. Lip, Hung-Ju Lin, Kuo-Liong Chien, Hsiu-Ching Hsu, Ta-Chen Su, Ming-Fong Chen, Yuan-Teh Lee Tags: Original Articles Source Type: research
