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Source: Catheterization and Cardiovascular Interventions
Condition: Thrombosis

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Total 43 results found since Jan 2013.

Effect of prior stroke on long ‐term outcomes of percutaneous coronary interventions in Chinese patients: A large single‐center study
ConclusionsPrior stroke history was the only predictor of risk of post ‐PCI stroke. The noncerebrovascular adverse events were not increased after adjusted analyses of baseline characteristics and propensity analyses.
Source: Catheterization and Cardiovascular Interventions - November 13, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Jing ‐Jing Xu, Ying Song, Ping Jiang, Zhan Gao, Jian‐Xin Li, Jue Chen, Yue‐Jin Yang, Run‐Lin Gao, Bo Xu, Jin‐Qing Yuan Tags: CORONARY ARTERY DISEASE Source Type: research

CYP2C19 pharmacogenetics versus standard of care dosing for selecting antiplatelet therapy in patients with coronary artery disease: A meta ‐analysis of randomized clinical trials
ConclusionIn patients undergoing stent implantation, MACE with genotype ‐guided therapy was not significantly reduced; however, there was a signal towards reduction of MACE in ACS patients, as well as a lower rate of MI, though this will require further confirmation in adequately powered trials.
Source: Catheterization and Cardiovascular Interventions - November 7, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Babikir Kheiri, Mohammed Osman, Ahmed Abdalla, Tarek Haykal, Pranay V. Pandrangi, Adam Chahine, Sahar Ahmed, Khansa Osman, Ghassan Bachuwa, Mustafa Hassan, Deepak L. Bhatt Tags: CORONARY ARTERY DISEASE Source Type: research

Complex coronary bifurcation treatment by a novel stenting technique: Bench test, fluid dynamic study and clinical outcomes
ConclusionsThe revascularization of complex large coronary bifurcation disease using the Nano‐crush technique appeared promising thanks to the favorable fluid dynamic profile, complete coverage of the SD ostium, and very small metal amount at the carina.
Source: Catheterization and Cardiovascular Interventions - January 25, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Gianluca Rigatelli, Marco Zuin, Fabio Dell'Avvocata, Dobrin Vassilev, Ramesh Daggubati, Thach Nguyen, Minh Tr í Nhân Nguyễn, Nicolas Foin Tags: CORONARY ARTERY DISEASE Source Type: research

Thromboembolism after WATCHMANTM in a clopidogrel non ‐responder: A case for concern?
Abstract Atrial fibrillation (AF) is associated with an increased risk of stroke and thromboembolism (TE). The WATCHMANTM left atrial appendage (LAA) closure device is indicated to reduce the risk of TE from the LAA in patients with non‐valvular AF. Here, we present a case of a patient with device‐related thrombus who suffered a TE event two months after WATCHMANTM LAA closure and two weeks after switching from aspirin plus warfarin to aspirin plus clopidogrel therapy. Laboratory investigation identified the patient to be hypercoagulable and to be a non‐responder to clopidogrel therapy. We discuss the potential role ...
Source: Catheterization and Cardiovascular Interventions - November 11, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Ganesh Venkataraman, Kevin P. Bliden, Udaya S. Tantry, Paul A. Gurbel Tags: VALVULAR AND STRUCTURAL HEART DISEASES Source Type: research

Interventional closure of patent foramen ovale with Nit ‐occlud® device in prevention of recurrent neurologic events—Long‐term results
ConclusionsThe Nit‐Occlud PFO device and its delivery system are safe and provides sufficient closure of PFO in patients who suffered from cryptogenic stroke, TIA or paradoxical peripheral embolism. It is associated with high procedural success and favorable rates of complete closure.
Source: Catheterization and Cardiovascular Interventions - October 25, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Aleksander Araszkiewicz, Sylwia S ławek, Olga Trojnarska, Maciej Lesiak, Marek Grygier Tags: VALVULAR AND STRUCTURAL HEART DISEASES Source Type: research

Single trans ‐septal access technique for left atrial intracardiac echocardiography to guide left atrial appendage closure
ConclusionsThis initial experience suggests that LAA occlusion with the Amplatzer Amulet device using ICE guidance from the left atrium via a single trans‐septal technique is feasible and safe.
Source: Catheterization and Cardiovascular Interventions - August 24, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Daniel Aguirre, Christian Pincetti, Luis Perez, Carlos Deck, Mario Alfaro, Maria Jesus Vergara, Gabriel Maluenda Tags: Valvular and Structural Heart Diseases Source Type: research

Duration of dual antiplatelet therapy following drug ‐eluting stent implantation: A systemic review and meta‐analysis of randomized controlled trials with longer follow up
ConclusionsIn the present analysis of RCTs with longer follow up (2 years or longer), S‐DAPT compared with L‐DAPT, was associated with higher rate of MI and lower rate of major bleeding without any significant difference in the rates of all cause mortality, cardiac mortality, ST, TVR, and stroke.
Source: Catheterization and Cardiovascular Interventions - May 30, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Abhishek Sharma, Sahil Agrawal, Aakash Garg, Ajay Vallakati, Carl J. Lavie, Gerald Helft Tags: CORONARY ARTERY DISEASE Source Type: research

Comparison of antithrombotic agents during urgent percutaneous coronary intervention following thrombolytic therapy: A retrospective cohort study
ConclusionIn STEMI patients undergoing PCI within 24 hr after thrombolytic therapy, bivalirudin was associated with a strong trend toward reduced bleeding complications as compared to heparin alone or heparin plus GPI.The optimal antithrombotic regiment for urgent PCI following thrombolytic therapy is currently unknown. Our study demonstrated that use of bivalirudin during PCI following thrombolytic therapy is associated with a trend toward reduced bleeding complications compared to heparin alone or heparin plus GPI. Large randomized trials of adjunctive anticoagulation during PCI in this complex post‐thrombolytic popula...
Source: Catheterization and Cardiovascular Interventions - April 18, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Jaya R. Mallidi, Peter Robinson, Paul F. Visintainer, Amir S. Lotfi, Scott Mulvey, Gregory R. Giugliano Tags: Coronary Artery Disease Source Type: research

Percutaneous coronary intervention or coronary artery bypass grafting for unprotected left main coronary artery disease
ConclusionsIn patients with unprotected left main coronary disease and low to intermediate SYNTAX score, PCI might be an acceptable alternative to CABG. © 2017 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - March 14, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Ahmed N. Mahmoud, Islam Y. Elgendy, Amgad Mentias, Marwan Saad, Walid Ibrahim, Mohammad K. Mojadidi, Ramez Nairooz, Parham Eshtehardi, R. David Anderson, Habib Samady Tags: Coronary Artery Disease Source Type: research

Manual thrombectomy efficiency in relationship to the area at risk in patients with myocardial infarction with TIMI 0 ‐1 coronary flow: Insights from an all comers registry
ConclusionIn comparison with the group where MT was inefficient, efficient MT may modestly reduce final infarct size without a significant clinical benefit. In comparison with PCI‐only, no difference was found regarding stroke. © 2017 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - February 12, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Andr é Luz, Inês Silveira, Bruno Brochado, Patrícia Rodrigues, Maria João Sousa, Raquel Santos, Maria Trêpa, Mário Santos, João Silveira, Severo Torres, Adelino F. Leite‐Moreira, Henrique Carvalho Tags: Coronary Artery Disease Source Type: research

Thrombotic valvular dysfunction with transcatheter mitral interventions for postsurgical failures
ConclusionThrombotic related dysfunction post‐TMVR occurred in 15% (2/13) of patients and one patient had abnormal leaflet thickening that may have been thrombus related. Dual‐antiplatelet therapy was used in all 3 cases suggesting the possible need for oral anticoagulation postmitral valve‐in‐valve therapy. © 2017 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - February 9, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Marvin H. Eng, Adam Greenbaum, Dee Dee Wang, Janet Wyman, DNP, Heider Arjomand, Pradeep Yadav, Hassan Nemeh, Gaetano Paone, Mayra Guerrero, William O'Neill Tags: Valvular and Structural Heart Diseases Source Type: research

Left atrial appendage closure: Initial experience with the ultraseal device
ConclusionsThis initial experience with the Ultraseal LAA closure device demonstrates preliminary safety and feasibility. Further larger studies with longer follow‐up are warranted. © 2016 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - November 16, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Ander Regueiro, Mathieu Bernier, Gilles O'Hara, Kim O'Connor, Jean ‐Michel Paradis, Jonathan Beaudoin, Tania Rodriguez‐Gabella, Jean Champagne, Josep Rodés‐Cabau Tags: Valvular and Structural Heart Diseases Source Type: research

Thrombus aspiration: Suck it up and keep looking for a niche
Key Points Thrombus aspiration in acute coronary syndrome PCI decreased angiographic stenosis and decreased IVUS‐assessed volume of lesions. Decrease in culprit lesion volume correlated with better stent expansion. This non‐randomized single‐center study demonstrated feasibility of thrombus aspiration pre‐PCI in ACS patients, but did not prove superiority to other methods of lesion preparation such as balloon pre‐dilatation. It is unlikely to be adopted into routine practice based on this study. Randomized studies large enough to compare clinical outcomes (e.g., stroke and death) would be necessary to prove the ...
Source: Catheterization and Cardiovascular Interventions - November 15, 2016 Category: Cardiovascular & Thoracic Surgery Authors: James C. Blankenship Tags: Coronary Artery Disease Source Type: research

Carotid artery stenting: Avoiding the perfect storm
Key Points Carotid artery stenting (CAS) and carotid artery endarterectomy (CEA) have achieved equipoise for most patients with carotid artery stenosis. Studies of outcomes after CAS and CEA must consider important patient and anatomic characteristics. A perfect storm for CAS is observed in a clinical scenario characterized by acute stroke, high likelihood for unstable plaque and thrombus, early revascularization, operator inexperience, and failure to use closed‐cell stents and embolic protection. Adverse outcomes in these situations are not shortcomings of CAS, but are due to poor clinical decision‐making and judgment.
Source: Catheterization and Cardiovascular Interventions - November 15, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Robert D. Safian Tags: Peripheral Vascular Disease Source Type: research

A mechanism for stroke complicating thrombus aspiration
We propose a mechanism of how stroke may be caused by thrombus aspiration during primary percutaneous coronary intervention (PPCI), and how it may be technique‐dependent. Two recent meta‐analyses report increased risk of stroke in patients undergoing routine thrombus aspiration during STEMI and the value of this technique has been controversial. The mechanism of stroke has not been fully explained. This case demonstrates 2 mechanisms by which aspiration might cause thrombus embolization. We recommend that if thrombus aspiration is performed during PPCI for STEMI, it should be done selectively and carefully. It is prude...
Source: Catheterization and Cardiovascular Interventions - October 2, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Eddie D. Brown, James C. Blankenship Tags: Coronary Artery Disease Source Type: research