• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Thrombus Enhancement Is a Predictor of Clinical Outcome in Acute Ischemic Stroke after Mechanical Thrombectomy
Conclusions: CE of thrombi – especially in a range from over 18.4 to 40.35 Hounsfield Units – is an independent predictor of poor clinical outcome in patients undergoing MT due to acute middle cerebral artery occlusion.Cerebrovasc Dis 2018;46:270 –278
Source: Cerebrovascular Diseases - January 15, 2019 Category: Neurology Source Type: research

Baseline Characteristics and Readmissions after Cerebral Venous Sinus Thrombosis in a Nationally Representative Database
Conclusions: We provide baseline characteristics and readmission rates after CVST over a 1-year period. In-hospital mortality rate and association with pregnancy were lower than previously observed.Cerebrovasc Dis 2018;46:249 –256
Source: Cerebrovascular Diseases - January 2, 2019 Category: Neurology Source Type: research

Ischemic Stroke: Histological Thrombus Composition and Pre-Interventional CT Attenuation Are Associated with Intervention Time and Rate of Secondary Embolism
Conclusions: Fibrin-rich thrombi with low erythrocyte percentage are significantly associated with longer intervention times. Embolisms in the thrombectomy process occur more often in thrombi with a small fraction of red blood cells and a low CT-density, suggesting a higher fragility of these thrombi.Cerebrovasc Dis 2017;44:344 –350
Source: Cerebrovascular Diseases - October 31, 2017 Category: Neurology Source Type: research

The Prevalence of and Factors Related to Vascular Hyperintensity on T1-Weighted Imaging in Acute Ischemic Stroke
Conclusion: The T1-HVS was observed in 4.5% of acute ischemic stroke patients. T1-HVSs appeared in the subacute phase in arteries with persistent occlusion and remained for a few months.Cerebrovasc Dis 2017;44:203-209
Source: Cerebrovascular Diseases - August 15, 2017 Category: Neurology Source Type: research

Free Fatty Acid Is Associated with Thrombogenicity in Cardioembolic Stroke
Background: Recently, the role of free fatty acids (FFAs) in thromboembolism has re-emerged in the context of cardioembolic stroke. Therefore, we attempted to determine the role of FFAs in embolic risk in various potential sources of cardioembolism (PSCE). We hypothesized that if elevated FFA levels in stroke patients are associated with thrombogenesis, then patients with a well-known high risk of embolic sources would have high FFA levels.Methods: Data collected from 2 hospital-based stroke registries were analyzed to investigate the association between FFA and PSCE.Results: A total of 2,770 acute stroke patients, includi...
Source: Cerebrovascular Diseases - July 17, 2017 Category: Neurology Source Type: research

Changes in Activated Thrombin-Activatable Fibrinolysis Inhibitor Levels Following Thrombolytic Therapy in Ischemic Stroke Patients Correlate with Clinical Outcome
Conclusion: These data demonstrate a consistent relationship between TAFI levels and early clinical severity during rt-PA treatment.Cerebrovasc Dis 2016;42:404-414
Source: Cerebrovascular Diseases - July 7, 2016 Category: Neurology Source Type: research

The Impact of Body Mass Index on the Thrombolytic Treatment of Acute Ischemic Stroke
Background: Body weight and body mass index (BMI) are regularly assessed factors in stroke patients for manifold reasons. However, their potential role specifically in intravenous thrombolysis has not been thoroughly examined. Methods: Data from 865 consecutive acute ischemic stroke patients treated with intravenous thrombolysis were analyzed. Patients were divided into different BMI categories (underweight, normal weight, overweight, obese) and compared based on the following factors: time window of treatment, clinical scores National Institute of Health Stroke Scale Score (NIHSS), modified Rankin scale (mRS) on admission...
Source: Cerebrovascular Diseases - May 13, 2016 Category: Neurology Source Type: research

The Mechanism of Procedural Stroke Following Carotid Endarterectomy within the Asymptomatic Carotid Surgery Trial 1
Conclusion: In ACST-1, the risk of procedural stroke was low. Most strokes (60%) occurred on the day of the procedure and were caused by thrombosis or thrombotic occlusion of the ipsilateral carotid artery. These findings emphasize the importance of immediate assessment of the treated carotid artery when a stroke occurs after CEA.Cerebrovasc Dis 2016;42:178-185
Source: Cerebrovascular Diseases - April 26, 2016 Category: Neurology Source Type: research

Stroke Mimics in a Stroke Care Pathway Based on MRI Screening
Conclusions: A rate of SM up to 38% of the code stroke system confirms the difficulty to distinguish clinically a stroke from another diagnosis. In this study, using cerebral MRI in first intention was of special interest in patients with acute neurological symptoms to differentiate an NVD from an SM.Cerebrovasc Dis 2016;42:205-212
Source: Cerebrovascular Diseases - April 25, 2016 Category: Neurology Source Type: research

Endovascular Treatment of Acute Ischemic Stroke Due to Tandem Occlusions: Large Multicenter Series and Systematic Review
Conclusions: Acute endovascular treatment of tandem anterior circulation occlusions yields good outcomes and has similar outcome predictors to isolated intracranial occlusions. Given their comparable clinical behavior, these patients should be included in future trials.Cerebrovasc Dis 2016;41:306-312
Source: Cerebrovascular Diseases - February 17, 2016 Category: Neurology Source Type: research

Clinical Presentation and Multi-Parametric Screening Surrogates of Ischemic Stroke Patients Suffering from Infective Endocarditis
Conclusions: IE in stroke patients is associated with worse clinical outcome, complicated by intravenously applied thrombolysis, and therefore needs to be screened during the early phase of hospitalization. Increased serum levels of CRP and leukocyte count in combination with an increased body temperature or abnormal cardiac murmurs should entail rapid initiation of further diagnostics, that is, transoesophageal echocardiography.Cerebrovasc Dis 2016;41:60-67
Source: Cerebrovascular Diseases - December 15, 2015 Category: Neurology Source Type: research

DWI Lesion Patterns Predict Outcome in Stroke Patients with Thrombolysis
Background: Lesion patterns may predict prognosis after acute ischemic stroke within the middle cerebral artery (MCA) territory; yet it remains unclear whether such imaging prognostic factors are related to patient outcome after intravenous thrombolysis. Aims: The aim of this study is to investigate the clinical outcome after intravenous thrombolysis in acute MCA ischemic strokes with respect to diffusion-weighted imaging (DWI) lesion patterns. Methods: Consecutive acute ischemic stroke cases of the MCA territory treated over a 7-year period were retrospectively analyzed. All acute MCA stroke patients underwent a MRI scan ...
Source: Cerebrovascular Diseases - October 30, 2015 Category: Neurology Source Type: research

Antiphospholipid Antibodies and Recurrent Thrombotic Events: Persistence and Portfolio
Conclusions: Rates of TOE/death were not influenced by aPL results at baseline or follow-up. Persistent anti-β2GPI alone, and with persistent second aPL, was independently associated with decreased time to TOE/death. Persistent aPL, an aPL portfolio and newer aPL in ischemic stroke patients are not helpful in predicting an increased rate of recurrent TOEs.Cerebrovasc Dis 2015;40:293-300
Source: Cerebrovascular Diseases - October 30, 2015 Category: Neurology Source Type: research

Prevalence of Pelvic Vein Pathology in Patients with Cryptogenic Stroke and Patent Foramen Ovale Undergoing MRV Pelvis
Conclusion: We demonstrate a relatively high prevalence of pelvic DVT among select CS patients emphasizing the importance of considering the pelvic veins as a potential source for emboli particularly in the presence of risk factors known to predispose DVT. Because patients were included at the treating physician's discretion, our results reflect ‘real-life' practice. Our results may be of clinical importance as inclusion of pelvic vein imaging in CS patients with PFO had impactful therapeutic and nosologic implications. Further study is needed to define patients most likely to benefit from pelvic vein imaging.Cerebrovasc Dis 2015;39:216-223
Source: Cerebrovascular Diseases - March 13, 2015 Category: Neurology Source Type: research

Determinants of Platelet-Leukocyte Aggregation and Platelet Activation in Stroke
Conclusions: The most important result of our study is that PLA and platelet activation are independent of other vascular risk factors correlated with stroke in our sample. In addition, we identified the missense SNP rs2228315 in the PSGL1-gene as a candidate polymorphism for ischemic stroke-related PLA. Association between this SNP and stroke as well as coronary artery disease has also been shown by two other studies.Cerebrovasc Dis 2015;39:176-180
Source: Cerebrovascular Diseases - February 26, 2015 Category: Neurology Source Type: research

Pages: 1  2  3