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COVID-19 Severity and Stroke: Correlation of Imaging and Laboratory Markers ADULT BRAIN
CONCLUSIONS: Patients with stroke hospitalized with severe COVID-19 are characterized by higher inflammatory, coagulopathy, and tissue-damage biomarkers, supporting proposed pathogenic mechanisms of hyperinflammation activating a prothrombotic state. Cautious balancing of thrombosis and the risk of hemorrhagic transformation is warranted when considering anticoagulation.
Source: American Journal of Neuroradiology - February 9, 2021 Category: Radiology Authors: Katz, J. M., Libman, R. B., Wang, J. J., Filippi, C. G., Sanelli, P., Zlochower, A., Gribko, M., Pacia, S. V., Kuzniecky, R. I., Najjar, S., Azhar, S. Tags: ADULT BRAIN Source Type: research

Characteristics of Large-Vessel Occlusion Associated with COVID-19 and Ischemic Stroke INTERVENTIONAL
SUMMARY: The mechanisms and phenotype of ischemic stroke associated with coronavirus disease 2019 (COVID-19) remain uncertain. A retrospective study was conducted in patients with COVID-19 presenting with ischemic stroke from March 1 to May 25, 2020, and cases with large-vessel occlusion were identified. To provide baseline institutional stroke data within and outside the COVID-19 pandemic, all consecutive ischemic stroke and TIA admissions (COVID and non-COVID) to the hospital during a 10-week period from March 1 to May 10, 2020, were collected and compared with data from the same time period in 2019. Among 20 patients wi...
Source: American Journal of Neuroradiology - December 11, 2020 Category: Radiology Authors: John, S., Kesav, P., Mifsud, V. A., Piechowski-Jozwiak, B., Dibu, J., Bayrlee, A., Elkambergy, H., Roser, F., Elhammady, M. S., Zahra, K., Hussain, S. I. Tags: INTERVENTIONAL Source Type: research

COVID-19-Associated Carotid Atherothrombosis and Stroke EXTRACRANIAL VASCULAR
We present a radiology-pathology case series of 3 patients with coronavirus disease 2019 (COVID-19) with acute ischemic stroke due to fulminant carotid thrombosis overlying mild atherosclerotic plaque and propose a novel stroke mechanism: COVID-associated carotid atherothrombosis.
Source: American Journal of Neuroradiology - November 11, 2020 Category: Radiology Authors: Esenwa, C., Cheng, N. T., Lipsitz, E., Hsu, K., Zampolin, R., Gersten, A., Antoniello, D., Soetanto, A., Kirchoff, K., Liberman, A., Mabie, P., Nisar, T., Rahimian, D., Brook, A., Lee, S.- K., Haranhalli, N., Altschul, D., Labovitz, D. Tags: EXTRACRANIAL VASCULAR Source Type: research

Intraluminal Carotid Artery Thrombus in COVID-19: Another Danger of Cytokine Storm? EXTRACRANIAL VASCULAR
We report a series of 6 patients with COVID-19 with acute ischemic stroke due to intraluminal carotid artery thrombus presenting during an 8-day period. Six patients were included (5 men) with a mean age of 65.8 years (range, 55–78 years). COVID-19 was diagnosed by detection of Severe Acute Respiratory Syndrome coronavirus 2 in 5 patients and was presumed due to typical clinical and imaging findings in 1 patient. All patients had vascular risk factors including diabetes (83%), hyperlipidemia (100%), and smoking (17%). Four patients presented with large infarcts with initial NIHSS scores of 24–30. During their h...
Source: American Journal of Neuroradiology - September 8, 2020 Category: Radiology Authors: Mohamud, A. Y., Griffith, B., Rehman, M., Miller, D., Chebl, A., Patel, S. C., Howell, B., Kole, M., Marin, H. Tags: EXTRACRANIAL VASCULAR Source Type: research