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Source: Cerebrovascular Diseases
Condition: Thrombosis
Education: Lessons

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Fifty Years of Acute Ischemic Stroke Treatment: A Personal History
Background: It has been 50 years since the first explorations of the physiology of cerebral ischemia by measuring cerebral blood flow (CBF), and 25 years since the approval of tissue plasminogen activator for treating acute ischemic stroke. My personal career began and matured during those eras. Here, I provide my perspective on the evolution of acute stroke research and treatment from 1971 to the present, with some in-depth discussion of the National Institutes of Neurologic Disease and Stroke (NINDS) tissue-type plasminogen activator (tPA) stroke trial and development of mobile stroke units.Summary: Studies of CBF and me...
Source: Cerebrovascular Diseases - October 14, 2021 Category: Neurology Source Type: research