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Pharmacist ’s knowledge regarding the management of overactive bladder in elderly women
Anticholinergic drugs used to treat overactive bladder (OAB), have common side effects, including constipation, dry eyes and dry mouth. They can also cause central nervous system effects such as confusion and reduction in cognitive function [1]. Polypharmacy and an increase in blood brain barrier permeability increase these effects [2] which, are more likely in the elderly [3] as aging, as well as trauma, multiple sclerosis, hypertension, stroke and diabetes [4], leads to increased blood brain barrier permeability.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - January 16, 2021 Category: OBGYN Authors: George Araklitis, Angie Rantell, Georgina Baines, Richard Flint, Dudley Robinson, Linda Cardozo Tags: Full length article Source Type: research