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Failure of Anticoagulation to Prevent Stroke in Context of Lupus-Associated Anti-Phospholipid Syndrome and Mild COVID-19
We present a 43-year-old female with a history of seropositive-antiphospholipid syndrome and systemic lupus erythematosus who developed an acute ischemic stroke in the setting of mild COVID-19 infection despite adherence to chronic systemic anticoagulation.
Source: Journal of Stroke and Cerebrovascular Diseases - April 12, 2021 Category: Neurology Authors: Keith J. Kincaid, Alexis N. Simpkins Source Type: research

Cerebral Venous Sinus Thrombosis as a Rare Complication of Systemic Lupus Erythematosus: Subgroup Analysis of the VENOST Study
Systemic lupus erythematosus (SLE) is an unusual risk factor for cerebral venous sinus thrombosis (CVST). As few CVST patients with SLE have been reported, little is known regarding its frequency as an underlying etiology, clinical characteristics, or long-term outcome. We evaluated a large cohort of CVST patients with SLE in a multicenter study of cerebral venous thrombosis, the VENOST study, and their clinical characteristics.
Source: Journal of Stroke and Cerebrovascular Diseases - September 23, 2019 Category: Neurology Authors: Task ın Duman, Seden Demirci, Derya Uluduz, Hasan Hüseyin Kozak, Serkan Demir, Cemile Handan Mısırlı, Hayriye Küçükoğlu, Nilgün Çınar, Füsun Mayda Domaç, Şerefnur Öztürk, VENOST Study Group, Mehmet Ali Sungur, Vildan Yayla, Ali Yavuz Kara Source Type: research

Vertebrobasilar Artery Stroke as the Heralding Sign of Systemic Lupus Erythematosus
This report details 3 different patients with SLE who experienced VBI as an initial manifestation. Patient 1 was a 24-year-old female who developed a bilateral pontine lesion as a consequence of basilar artery stenosis. Patient 2 was a 34-year-old male with an acute ischemic lesion on the right side of his cerebellum and pons because of significant stenosis in the distal segment of the right vertebral artery.
Source: Journal of Stroke and Cerebrovascular Diseases - January 3, 2018 Category: Neurology Authors: Reza Mohammadian, Ali Tarighatnia, Mehran Naghibi, Evin Koleini, Nader D. Nader Tags: Case Studies Source Type: research

Numerous Fusiform and Saccular Cerebral Aneurysms in Central Nervous System Lupus Presenting with Ischemic Stroke
We report a patient with an active SLE flare who presented with a recurrent ischemic stroke and was found to have numerous unruptured fusiform and saccular aneurysms in multiple vascular territories. He was treated with high-dose steroid and rituximab along with aspirin and blood pressure control for stroke prevention.
Source: Journal of Stroke and Cerebrovascular Diseases - May 4, 2017 Category: Neurology Authors: Shahram Majidi, Christopher R. Leon Guerrero, Shreya Gandhy, Kathleen M. Burger, Dimitri Sigounas Tags: Case Studies Source Type: research

Cerebral Venous Sinus Thrombosis Presenting Feature of Systemic Lupus Erythematosus
CVST (cerebral venous sinus thrombosis) may sometimes be associated with autoimmune disorders that require specific treatment. The clinical and magnetic resonance imaging (MRI) findings of systemic lupus erythematosus (SLE) patients with CVST are presented and contrasted with CVST without SLE.
Source: Journal of Stroke and Cerebrovascular Diseases - January 4, 2017 Category: Neurology Authors: Rajesh Kumar Singh, Sanjeev Kumar Bhoi, Jayantee Kalita, Usha Kant Misra Source Type: research

Bilateral Central Retinal Artery Occlusion in a Patient with Systemic Lupus Erythematosus
We report a case of a 20-year-old woman with newly diagnosed SLE, who awoke with bilateral simultaneous central retinal artery occlusion (CRAO). Her antiphospholipid antibody panel was normal. Vision did not recover after treatment with steroids and anticoagulation. This case suggests that such patients may be in hypercoagulable status even with negative antiphospholipid antibodies. Severe ocular complication such as CRAO may occur during the early disease process.
Source: Journal of Stroke and Cerebrovascular Diseases - April 20, 2015 Category: Neurology Authors: Li Hua, Ketan Patel, James J. Corbett Tags: Case Report Source Type: research