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Condition: Hemorrhagic Stroke
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Total 19785 results found since Jan 2013.
Rheumatic Mitral Valve Disease Is Associated With Worse Outcomes in Stroke Clinical Sciences
We examined the association between RMVD and both serious and common cardiovascular and noncardiovascular (respiratory and infective) complications in a cohort of hospitalized stroke patients based in Thailand. Factors associated with in-hospital mortality were also explored. Data were obtained from a National Insurance Database. All hospitalized strokes between October 1, 2004, and January 31, 2013, were included in the current study. Characteristics and outcomes were compared for RMVD and non-RMVD patients. Logistic regression, propensity score matching, and multivariate models were used to assess study outcomes.Resultsâ...
Source: Stroke - October 23, 2016 Category: Neurology Authors: Wood, A. D., Mannu, G. S., Clark, A. B., Tiamkao, S., Kongbunkiat, K., Bettencourt-Silva, J. H., Sawanyawisuth, K., Kasemsap, N., Barlas, R. S., Mamas, M., Myint, P. K. Tags: Rheumatic Heart Disease, Valvular Heart Disease, Complications, Mortality/Survival, Cerebrovascular Disease/Stroke Original Contributions Source Type: research
Automated Software System to Promote Anticoagulation and Reduce Stroke Risk Brief Report
Conclusions—No significant change in OAC prescribing occurred. A greater rate of diagnosis of transient ischemic attack (possibly because of improved detection or overdiagnosis) was associated with a reduction (of borderline significance) in stroke and hemorrhage over 12 months.Clinical Trial Registration—URL: http://www.isrctn.com. Unique Identifier: ISRCTN55722437.
Source: Stroke - February 26, 2017 Category: Neurology Authors: Tim A. Holt, Andrew Dalton, Tom Marshall, Matthew Fay, Nadeem Qureshi, Susan Kirkpatrick, Jenny Hislop, Daniel Lasserson, Karen Kearley, Jill Mollison, Ly-Mee Yu, F.D. Richard Hobbs, David Fitzmaurice Tags: Atrial Fibrillation, Anticoagulants, Health Services, Ischemic Stroke Brief Reports Source Type: research
Successful Reperfusion With Mechanical Thrombectomy Is Associated With Reduced Disability and Mortality in Patients With Pretreatment Diffusion-Weighted Imaging-Alberta Stroke Program Early Computed Tomography Score
Background and Purpose—In acute ischemic stroke patients, diffusion-weighted imaging (DWI)–Alberta Stroke Program Early Computed Tomography Score (ASPECTS) is correlated with infarct volume and is an independent factor of functional outcome. Patients with pretreatment DWI-ASPECTS ≤6 were excluded or under-represented in the recent randomized mechanical thrombectomy trials. Our aim was to assess the impact of reperfusion in pretreatment DWI-ASPECTS ≤6 patients treated with mechanical thrombectomy.Methods—We analyzed data collected between January 2012 and August 2015 in a bicentric prospective clinical registry of...
Source: Stroke - March 27, 2017 Category: Neurology Authors: Jean–Philippe Desilles, Arthuro Consoli, Hocine Redȷem, Oguzhan Coskun, Gabriele Ciccio, Stanislas Smaȷda, Julien Labreuche, Cristian Preda, Clara Ruiz Guerrero, Jean–Pierre Decroix, Georges Rodesch, Mikael Mazighi, Raphael Blanc Tags: Magnetic Resonance Imaging (MRI), Revascularization, Cerebrovascular Disease/Stroke, Cerebrovascular Procedures, Ischemic Stroke Original Contributions Source Type: research
PAIS 2 (Paracetamol Acetaminophen in Stroke 2) Clinical Sciences
Conclusions—Treatment with high-dose paracetamol seemed to be safe. The effect of high-dose paracetamol on functional outcome remains uncertain. Therefore, a large trial of early treatment with high-dose paracetamol is still needed.Clinical Trial Registration—URL: http://www.trialregister.nl. Unique identifier: NTR2365.
Source: Stroke - March 27, 2017 Category: Neurology Authors: Inger R. de Ridder, Heleen M. den Hertog, H. Maarten A. van Gemert, A.H.C.M.L. (Tobien) Schreuder, Annemieke Ruitenberg, E. (Lisette) Maasland, Ritu Saxena, Jordie H. van Tuijl, Ben P.W. Jansen, Renske M. Van den Berg-Vos, Frederique Vermeij, Peter J. Kou Tags: Pharmacology, Meta Analysis, Quality and Outcomes, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research
Clinical Significance of Wall Changes After Recanalization Therapy in Acute Stroke Brief Report
Conclusions—The use of high-resolution vessel wall imaging after successful recanalization can provide information about postrecanalization arterial wall changes and clinical outcomes.
Source: Stroke - March 27, 2017 Category: Neurology Authors: Woo-Keun Seo, Kyungmi Oh, Sang-il Suh, Hae Young Seol Tags: Magnetic Resonance Imaging (MRI), Quality and Outcomes, Cerebrovascular Procedures, Ischemic Stroke Brief Reports Source Type: research
Baseline Blood Pressure Effect on the Benefit and Safety of Intra-Arterial Treatment in MR CLEAN (Multicenter Randomized Clinical Trial of Endovascular Treatment of Acute Ischemic Stroke in the Netherlands) Clinical Sciences
Conclusions—BP does not affect the benefit or safety of IAT in patients with acute ischemic stroke caused by proximal intracranial vessel occlusion. Our data provide no arguments to withhold or delay IAT based on BP.Clinical Trial Registration—URL: http://www.isrctn.com. Unique identifier: ISRCTN10888758.
Source: Stroke - June 26, 2017 Category: Neurology Authors: Maxim J.H.L. Mulder, Saliha Ergezen, Hester F. Lingsma, Olvert A. Berkhemer, Puck S.S. Fransen, Debbie Beumer, Lucie A. van den Berg, Geert Lycklama a Niȷeholt, Bart J. Emmer, H. Bart van der Worp, Paul J. Nederkoorn, Yvo B.W.E.M. Roos, Robert J. v Tags: High Blood Pressure, Revascularization, Stent, Cerebrovascular Disease/Stroke, Cerebrovascular Procedures Original Contributions Source Type: research
Anesthesia-Related Outcomes for Endovascular Stroke Revascularization Clinical Sciences
Conclusions—Acute ischemic stroke patients undergoing intra-arterial therapy may have worse outcomes when treated with GA as compared with conscious sedation/local anesthesia. However, major limitations of current evidence (ie, retrospective studies and selection bias) indicate a need for adequately powered, multicenter randomized controlled trials to answer this question.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Waleed Brinjikji, Jeffrey Pasternak, Mohammad H. Murad, Harry J. Cloft, Tasha L. Welch, David F. Kallmes, Alejandro A. Rabinstein Tags: Revascularization, Cerebrovascular Procedures, Ischemic Stroke Original Contributions Source Type: research
Cost-Effectiveness of Thrombectomy in Patients With Acute Ischemic Stroke Clinical Sciences
Conclusions—Based on randomized trial data, this study demonstrates that IVMT used to treat acute ischemic stroke is cost-effective when compared with IVT alone.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT01062698.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Hamza Achit, Marc Soudant, Kossar Hosseini, Aurelie Bannay, Jonathan Epstein, Serge Bracard, Francis Guillemin Tags: Cost-Effectiveness, Ischemic Stroke Original Contributions Source Type: research
Intracerebral Hemorrhage and Outcome After Thrombolysis in Stroke Patients Using Selective Serotonin-Reuptake Inhibitors Clinical Sciences
Background and Purpose—Selective serotonin-reuptake inhibitors (SSRIs) impair platelet function and have been linked to a higher risk of spontaneous intracerebral hemorrhage—an association that may be augmented by oral anticoagulants (OAC). We aimed to assess whether preadmission treatment with SSRIs in patients with acute ischemic stroke is associated with post-thrombolysis symptomatic intracerebral hemorrhage (sICH) and functional outcome.Methods—A multicenter retrospective analysis was conducted in prospective registries of patients treated by thrombolysis within 4.5 hours of stroke onset. The association between ...
Source: Stroke - November 27, 2017 Category: Neurology Authors: Jan F. Scheitz, Guillaume Turc, Linda Kuȷala, Alexandros A. Polymeris, Mirȷam R. Heldner, Thomas P. Zonneveld, Hebun Erdur, Sami Curtze, Christopher Traenka, Celine Breniere, Roland Wiest, Andrea Rocco, Gerli Sibolt, Henrik Gensicke, Matthia Tags: Complications, Ischemic Stroke Original Contributions Source Type: research
Echocardiographic Risk Factors for Stroke and Outcomes in Patients With Atrial Fibrillation Anticoagulated With Apixaban or Warfarin Clinical Sciences
Conclusions—In anticoagulated patients with atrial fibrillation and risk factors for stroke, echocardiographic findings do not seem to add to the risk of thromboembolic events.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT00412984.
Source: Stroke - November 27, 2017 Category: Neurology Authors: Dragos Vinereanu, Renato D. Lopes, Hillary Mulder, Bernard J. Gersh, Michael Hanna, Pedro G.M. de Barros e Silva, Dan Atar, Lars Wallentin, Christopher B. Granger, John H. Alexander Tags: Arrhythmias, Echocardiography, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research
Contact Aspiration Versus Stent Retriever in Patients With Acute Ischemic Stroke With M2 Occlusion in the ASTER Randomized Trial (Contact Aspiration Versus Stent Retriever for Successful Revascularization) Brief Report
Conclusions—First-line mechanical thrombectomy with CA compared with SR did not result in an increased successful revascularization rate in patients with acute stroke with isolated M2 occlusion.
Source: Stroke - January 22, 2018 Category: Neurology Authors: Benjamin Gory, Bertrand Lapergue, Raphael Blanc, Julien Labreuche, Malek Ben Machaa, Alain Duhamel, Gautier Marnat, Suzana Saleme, Vincent Costalat, Serge Bracard, Hubert Desal, Mikael Mazighi, Arturo Consoli, Michel Piotin, for the ASTER Trial Investiga Tags: Revascularization, Stent, Treatment, Complications, Ischemic Stroke Brief Reports Source Type: research
Childhood Stature and Growth in Relation to First Ischemic Stroke or Intracerebral Hemorrhage Clinical Sciences
Conclusions—Short stature at 7 to 13 years is significantly associated with increased risks of IS in both sexes and with ICH in men. Growth during this period of childhood is not significantly associated with either of these stroke subtypes, suggesting that underlying mechanisms linking height with risks of stroke may exert their influence already by early childhood.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Line Klingen Gȷarde, Thomas Clement Truelsen, Jennifer Lyn Baker Tags: Etiology, Epidemiology, Pediatrics, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research
Long-Term Risk of Hemorrhagic Stroke in Young Patients With Congenital Heart Disease Clinical Sciences
Conclusions—The relative risk of hemorrhagic stroke among children and young adults with CHD was almost 8× higher than that of matched controls from the general population, although the absolute risk was low. The highest risk of ICH and SAH occurred in patients with severe nonconotruncal defects and coarctation of the aorta.
Source: Stroke - April 23, 2018 Category: Neurology Authors: Kok Wai Giang, Zacharias Mandalenakis, Mikael Dellborg, Georgios Lappas, Peter Eriksson, Per-Olof Hansson, Annika Rosengren Tags: Epidemiology, Cerebrovascular Disease/Stroke, Cerebrovascular Malformations, Intracranial Hemorrhage Original Contributions Source Type: research
Impact of Smoking on Clinical Outcome and Recanalization After Intravenous Thrombolysis for Stroke Clinical Sciences
Conclusions—Our study suggests that good outcome in smokers is mainly related to differences in baseline characteristics and not to biological effects of smoking. The higher recanalization rates in smokers, however, call for further studies.
Source: Stroke - April 23, 2018 Category: Neurology Authors: Rebekka Kurmann, Stefan T. Engelter, Patrik Michel, Andreas R. Luft, Susanne Wegener, Meret Branscheidt, Elissavet Eskioglou, Gaia Sirimarco, Philippe A. Lyrer, Henrik Gensicke, Thomas Horvath, Urs Fischer, Marcel Arnold, Hakan Sarikaya Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research
Human Neural Stem Cell Extracellular Vesicles Improve Recovery in a Porcine Model of Ischemic Stroke Basic Sciences
Conclusions—This study demonstrated for the first time that in a large animal model novel NSC EVs significantly improved neural tissue preservation and functional levels post-MCAO, suggesting NSC EVs may be a paradigm changing stroke therapeutic.
Source: Stroke - April 23, 2018 Category: Neurology Authors: Robin L. Webb, Erin E. Kaiser, Brian J. Jurgielewicz, Samantha Spellicy, Shelley L. Scoville, Tyler A. Thompson, Raymond L. Swetenburg, David C. Hess, Franklin D. West, Steven L. Stice Tags: Animal Models of Human Disease, Basic Science Research, Translational Studies, Treatment, Ischemic Stroke Original Contributions Source Type: research
