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Source: Neurosurgical Focus
Condition: Hemorrhagic Stroke

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Total 235 results found since Jan 2013.

Inpatient virtual shared medical appointments to improve health literacy, increase patient self-efficacy, and reduce provider burnout in acute cerebrovascular pathology patients and their caregivers: a pilot study
CONCLUSIONS: Implementation of a vSMA program at a tertiary care center during a pandemic was feasible. Themes caregivers expressed on the postsession survey included better understanding of caring for a stroke patient and coping with the unpredictability of a patient's prognosis. The pandemic has precipitated shifts toward telehealth, but this study highlights the importance of avoiding marginalization of elderly and less technologically inclined populations.PMID:35921191 | DOI:10.3171/2022.4.FOCUS21764
Source: Neurosurgical Focus - August 3, 2022 Category: Neurosurgery Authors: Uma V Mahajan Neha Sharma Marquis Maynard Lei Kang Collin M Labak Alankrita Raghavan Martha Sajatovic Alan Hoffer Berje H Shammassian James M Wright Xiaofei Zhou Christina Huang Wright Source Type: research

Emerging experimental therapies for intracerebral hemorrhage: targeting mechanisms of secondary brain injury.
This article reviews the pathophysiology of secondary brain injury relevant to ICH, examines pertinent experimental models, and highlights emerging therapeutic strategies. Treatment paradigms discussed include thrombin inhibitors, deferoxamine, minocycline, statins, granulocyte-colony stimulating factors, and therapeutic hypothermia. Despite promising experimental and preliminary human data, further studies are warranted prior to effective clinical translation. PMID: 23634928 [PubMed - in process]
Source: Neurosurgical Focus - May 1, 2013 Category: Neurosurgery Authors: Belur PK, Chang JJ, He S, Emanuel BA, Mack WJ Tags: Neurosurg Focus Source Type: research

Dabigatran, intracranial hemorrhage, and the neurosurgeon.
Abstract Dabigatran etexilate (Pradaxa) is a novel oral anticoagulant that has gained FDA approval for the prevention of ischemic stroke and systemic embolism in patients with nonvalvular atrial fibrillation. In randomized trials, the incidence of hemorrhagic events has been demonstrated to be lower in patients treated with dabigatran compared with the traditional anticoagulant warfarin. However, dabigatran does not have reliable laboratory tests to measure levels of anticoagulation and there is no pharmacological antidote. These drawbacks are challenging in the setting of intracerebral hemorrhage. In this article...
Source: Neurosurgical Focus - May 1, 2013 Category: Neurosurgery Authors: Awad AJ, Walcott BP, Stapleton CJ, Yanamadala V, Nahed BV, Coumans JV Tags: Neurosurg Focus Source Type: research

Decompressive hemicraniectomy without clot evacuation in dominant-sided intracerebral hemorrhage with ICP crisis.
Conclusions Decompressive hemicraniectomy without clot evacuation appears feasible in patients with large ICH and deserves further investigation, preferably in a randomized controlled setting. PMID: 23634923 [PubMed - in process]
Source: Neurosurgical Focus - May 1, 2013 Category: Neurosurgery Authors: Heuts SG, Bruce SS, Zacharia BE, Hickman ZL, Kellner CP, Sussman ES, McDowell MM, Bruce RA, Connolly ES Tags: Neurosurg Focus Source Type: research

Alpha-7 nicotinic acetylcholine receptor agonists in intracerebral hemorrhage: an evaluation of the current evidence for a novel therapeutic agent.
Abstract Intracerebral hemorrhage (ICH) is the most deadly and least treatable subtype of stroke, and at the present time there are no evidence-based therapeutic interventions for patients with this disease. Secondary injury mechanisms are known to cause substantial rates of morbidity and mortality following ICH, and the inflammatory cascade is a major contributor to this post-ICH secondary injury. The alpha-7 nicotinic acetylcholine receptor (α7-nAChR) agonists have a well-established antiinflammatory effect and have been shown to attenuate perihematomal edema volume and to improve functional outcome in experime...
Source: Neurosurgical Focus - May 1, 2013 Category: Neurosurgery Authors: Sussman ES, Kellner CP, McDowell MM, Bruce SS, Heuts SG, Zhuang Z, Bruce RA, Claassen J, Connolly ES Tags: Neurosurg Focus Source Type: research

Complications after mesial temporal lobe surgery via inferiortemporal gyrus approach.
Conclusions The inferior temporal gyrus approach to mesial temporal lobe resection is a safe and effective method for treating temporal lobe epilepsy. Morbidity and mortality rates associated with this procedure are lower than those associated with other neurosurgical procedures. The finding that surgical complications seem to be more common among older patients emphasizes the need for early surgical referral of patients with medically refractory epilepsy. PMID: 23724836 [PubMed - in process]
Source: Neurosurgical Focus - June 1, 2013 Category: Neurosurgery Authors: Vale FL, Reintjes S, Garcia HG Tags: Neurosurg Focus Source Type: research

Selective dorsal rhizotomy for spasticity not associated with cerebral palsy: reconsideration of surgical inclusion criteria.
Abstract Children with spastic diplegia from cerebral palsy (CP) experience measurable improvement in their spasticity and motor function following selective dorsal rhizotomy (SDR). The role of this operation in the treatment of other spasticity causes is less well defined. A literature review was undertaken to survey outcomes from SDRs performed outside the CP population. Multiple sclerosis was the most common diagnosis found, accounting for 74 of 145 patients described. Selective dorsal rhizotomies have also been reported in patients with traumatic brain and spinal cord injuries, ischemic and hemorrhagic stroke,...
Source: Neurosurgical Focus - November 1, 2013 Category: Neurosurgery Authors: Gump WC, Mutchnick IS, Moriarty TM Tags: Neurosurg Focus Source Type: research

Endovascular management of cerebral vasospasm.
Abstract Cerebral vasospasm remains a feared complication from subarachnoid hemorrhage. Vasospasm typically occurs from three to fourteen days post-aneurysm rupture, with peak risk on Day 7. Up to 50% of patients with angiographic vasospasm will subsequently develop delayed cerebral ischemia; 15-20% of this subset will develop stroke or death despite maximal medical therapy. We define symptomatic vasospasm as the presence of neurological worsening after exclusion of other identifiable causes, such as seizure, hydrocephalus, intracerebral hemorrhage, or metabolic dysfunction. This video demonstrates the set-up and ...
Source: Neurosurgical Focus - July 1, 2014 Category: Neurosurgery Authors: Kelman C, Reavey-Cantwell J Tags: Neurosurg Focus Source Type: research

Management of intracranial aneurysms associated with arteriovenous malformations.
The objective of this review is to discuss the demographics, natural history, classification, and strategies for management of BAVMs associated with IAs. PMID: 25175430 [PubMed - in process]
Source: Neurosurgical Focus - September 1, 2014 Category: Neurosurgery Authors: Flores BC, Klinger DR, Rickert KL, Barnett SL, Welch BG, White JA, Batjer HH, Samson DS Tags: Neurosurg Focus Source Type: research

Revisiting secondary normal pressure hydrocephalus: does it exist? A review.
CONCLUSIONS Secondary NPH encompasses a diverse group of clinical manifestations associated with a subset of patients with acquired hydrocephalus. The most common etiologies of sNPH include SAH and traumatic brain injury. Secondary NPH does indeed exist, and should be differentiated from idiopathic NPH based on outcome and on clinical, pathophysiological, and epidemiological characteristics, but should not be considered as a separate entity. PMID: 27581318 [PubMed - in process]
Source: Neurosurgical Focus - August 31, 2016 Category: Neurosurgery Authors: Daou B, Klinge P, Tjoumakaris S, Rosenwasser RH, Jabbour P Tags: Neurosurg Focus Source Type: research

Hydrocephalus associated with childhood nonaccidental head trauma.
CONCLUSIONS PTV presents early after NAHT, particularly after a DC has been performed. However, the authors found that only a few PTV/NAHT patients developed shunt-dependent hydrocephalus. PMID: 27798981 [PubMed - in process]
Source: Neurosurgical Focus - October 31, 2016 Category: Neurosurgery Authors: Vadivelu S, Rekate HL, Esernio-Jenssen D, Mittler MA, Schneider SJ Tags: Neurosurg Focus Source Type: research