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Specialty: Drugs & Pharmacology
Condition: Hemorrhagic Stroke
Management: Hospitals

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Total 17 results found since Jan 2013.

The Role of Statin Therapy in Hemorrhagic Stroke
The 3‐hydroxy‐3‐methylglutaryl coenzyme A reductase inhibitors (statins) are the most widely utilized class of cholesterol‐lowering agents, carrying multiple indications for both primary and secondary cardiovascular risk reduction. Concern was raised by previously published post hoc analyses and observational studies that noted an increased risk of hemorrhagic stroke in patients receiving a statin. Subsequent studies have demonstrated conflicting results regarding the role of statin therapy on hemorrhagic stroke risk and patient outcomes. New evidence suggests that statins taken prior to or continued during admissi...
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - December 19, 2015 Category: Drugs & Pharmacology Authors: Andrea Sikora Newsome, Bryan C. Casciere, J. Dedrick Jordan, Denise H. Rhoney, Kelly A. Sullivan, Kathryn A. Morbitzer, Joseph D. Moore, Emily A. Durr Tags: Review of Therapeutics Source Type: research

Complications associated with recombinant tissue plasminogen activator therapy for acute ischaemic stroke.
Abstract Intravenous recombinant human tissue plasminogen activato (rtPA, formulated as alteplase) is the primary therapy for acute ischaemic stroke by breaking down a clot of an occluded vessel. There are several randomised controlled trials and observational studies that support the use of rtPA to improve functional outcome following acute ischaemic stroke. However, thrombolytic therapy with rtPA can be associated with a number of complications. Many of the rtPA-related complications result from its thrombolytic action including bleeding (intracerebral and systemic haemorrhage), reperfusion injury with oedema, a...
Source: CNS and Neurological Disorders Drug Targets - February 4, 2013 Category: Drugs & Pharmacology Authors: Balami JS, Sutherland BA, Buchan AM Tags: CNS Neurol Disord Drug Targets Source Type: research