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Condition: Hemorrhagic Stroke
Education: Academia

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Total 250 results found since Jan 2013.

Multicenter assessment of morbidity associated with cerebral arteriovenous malformation hemorrhages
Conclusions The morbidity associated with cerebral AVM rupture appeared to be higher in our study than previously reported. Morbidity from AVM rupture should be considered as an important factor, together with variables such as risk of AVM rupture and procedural risk, in determining the optimal treatment strategy for unruptured cerebral AVMs.
Source: Journal of NeuroInterventional Surgery - June 16, 2017 Category: Neurosurgery Authors: Fukuda, K., Majumdar, M., Masoud, H., Nguyen, T., Honarmand, A., Shaibani, A., Ansari, S., Tan, L. A., Chen, M. Tags: Hemorrhagic stroke Source Type: research

Use of Platelet Function Testing Before Pipeline Embolization Device Placement Clinical Sciences
Conclusions—Clopidogrel nonresponders experienced a significantly higher rate of thromboembolic complications when compared with clopidogrel responders. However, this risk seems to be mitigated in nonresponders who were switched to ticagrelor or received a clopidogrel boost within 24 hours pre-procedure.
Source: Stroke - April 24, 2017 Category: Neurology Authors: Nimer Adeeb, Christoph J. Griessenauer, Paul M. Foreman, Justin M. Moore, Hussain Shallwani, Rouzbeh Motiei-Langroudi, Abdulrahman Alturki, Adnan H. Siddiqui, Elad I. Levy, Mark R. Harrigan, Christopher S. Ogilvy, Ajith J. Thomas Tags: Treatment, Cerebral Aneurysm, Cerebrovascular Disease/Stroke, Cerebrovascular Procedures Original Contributions Source Type: research

Role Of Sulfonylureas In Perihematomal Edema In Spontaneous Intracerebral Hemorrhage (N8.002)
Conclusions:Our study shows a trend towards decreased absolute PHE and better clinical outcomes in ICH patients with diabetes who are taking SUs. However, our findings are limited by the study design, low power, and imbalances in baseline ICH volume. Further studies are required to evaluate the role of SUs in attenuating PHE.Disclosure: Dr. Male has nothing to disclose. Dr. Robertson has nothing to disclose. Dr. Alkuwaiti has nothing to disclose. Dr. Bell has nothing to disclose. Dr. Lindsay has nothing to disclose. Dr. Reshi has nothing to disclose. Dr. Ezzeddine has received personal compensation for activities with Air ...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Male, S., Robertson, J., Alkuwaiti, M., Bell, C., Lindsay, D., Reshi, R., Ezzeddine, M., Streib, C. Tags: Neuroscience in the Clinic: Novel Therapeutic Targets in Critical Care Neurology: Intracerebral and Intraventricular Hemorrhage Source Type: research

Ultra-short door-to-needle times of 10 minutes or less in stroke thrombolysis - experience from 63 cases (S8.002)
Conclusions:An ultra-short DNT ≤10 minutes can be achieved safely in unequivocal clinical scenarios, with pre-notification of the multidisciplinary stroke team practically being a sine-qua-non.Disclosure: Dr. Topakian has nothing to disclose. Dr. Hörmanseder has nothing to disclose. Dr. Einsiedler has nothing to disclose. Dr. Straka has nothing to disclose. Dr. Oel has nothing to disclose. Dr. Metschitzer has nothing to disclose. Dr. Pischinger has nothing to disclose. Dr. Groicher has nothing to disclose. Dr. Müller has nothing to disclose. Dr. Vollmann has nothing to disclose. Dr. Kure has nothing to disclos...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Topakian, R., Hormanseder, B., Einsiedler, S., Straka, U., Oel, D., Metschitzer, B., Pischinger, B., Groicher, S., Muller, P., Vollmann, P., Kure, V., Farmer, D., Mezger, M., Wimmer, F., Sperl, W., Karrer, A., Funk, S., Lampl, R., Lugmayr, H., Schusterede Tags: Cerebrovascular Disease and Interventional Neurology: Acute Stroke Treatment Source Type: research

Elevated ventricular CSF lactate within the first week after aneurysmal subarachnoid hemorrhage is associated with poor outcome (P5.068)
Conclusions:Elevated CSF lactate drawn within the first week of hospitalization following aSAH correlates with outcome. Larger prospective studies are needed to test the validity of this data for predicting outcome and for understanding the pathophysiologic mechanisms.Study Supported by: No funding was received for this study.Disclosure: Dr. Renfrow has nothing to disclose. Dr. Wilson has nothing to disclose. Dr. Arnel has nothing to disclose. Dr. Wolfe has nothing to disclose. Dr. Datar has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Renfrow, J., Wilson, T., Arnel, M., Wolfe, S., Datar, S. Tags: Neurocritical Care: Subarachnoid Hemorrhage Source Type: research

Early Clinical Improvement in Central Retinal Artery Occlusion is Associated with Central Retinal Artery Recanalization (P4.262)
Conclusions:In our case series, no patient without early recanalization of the CRA had ECI. Further studies are merited to determine the impact of CRA recanalization timing and, furthermore, whether fibrinolytic therapy is associated with improved CRA recanalization rates and long-term visual acuity in CRAO patients.Disclosure: Dr. Alkuwaiti has nothing to disclose. Dr. Male has nothing to disclose. Dr. Hendriksen has nothing to disclose. Dr. Engel has nothing to disclose. Dr. Reshi has nothing to disclose. Dr. Ezzeddine has received personal compensation for activities with Air Liquide as a Scientific Advisory Board membe...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Alkuwaiti, M., Male, S., Hendriksen, S., Engel, K., Reshi, R. A., Ezzeddine, M., Emiru, T., Logue, C., Streib, C. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

Symptomatic Intracranial Hemorrhage after IV tPA for Acute Ischemic Stroke Patients with Relative Contraindications to Treatment (P4.267)
Conclusions:12 AIS patients with Class 3 exclusion criteria were treated with IV tPA. Our eight cases of IV tPA in pICH patients adds substantially to the existing literature. In this study, 25% of patients with pICH developed symptomatic ICH after IV tPA. Although the low number of eligible patients limits interpretation of our findings, continued caution when considering IV tPA for AIS patients with pICH may be warranted. More data is needed to clarify the impact these relative contraindications have on the treatment of AIS.Disclosure: Dr. Smith has nothing to disclose. Dr. Alkuwaiti has nothing to disclose. Dr. Bell has...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Smith, K., Alkuwaiti, M., Bell, C., Lindsay, D., Heyer, A., Reshi, R., Ezzeddine, M., Streib, C. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

Target Stroke Implementation: Best Practice Strategies Cut Thrombolysis Time to < 30 minutes in a 1,550 Bed Academic Urban County Hospital (P4.280)
Conclusions:Individualized hospital gap analysis identifies targeted interventions to shorten treatment times. DTN and DTG time can be reduced with implementation of simple, low-cost interventions, with persistent effect and no increase in symptomatic intracranial hemorrhage or stroke mimic treatment.Disclosure: Dr. Marulanda-Londoño has nothing to disclose. Dr. Bhatt has nothing to disclose. Dr. Atchaneeyasakul has nothing to disclose. Dr. Asdaghi has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Akram has nothing to disclose. Dr. Zhang has nothing to disclose. Dr. D’Amour has nothing to disclos...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Marulanda-Londono, E., Bhatt, N., Atchaneeyasakul, K., Asdaghi, N., Malik, A., Akram, N., Zhang, T., DAmour, D., Hesse, K., Sacco, R., Romano, J. Tags: Thrombolysis and Acute Evaluation in Ischemic Stroke Source Type: research

Analysis of current clinical practice on initiation of anticoagulation in patients with acute ischemic stroke. (P4.298)
Conclusions:Physicians with a subspecialty in vascular neurology, those with more years of experience in practice, and those practicing at academic institutions tended to initiate anticoagulation later.Disclosure: Dr. Olivas has nothing to disclose. Dr. Ajani has nothing to disclose. Dr. Yao has nothing to disclose. Dr. Sangha has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Olivas, E., Ajani, Z., Yao, J., Sangha, N. Tags: In-Hospital Stroke Care Source Type: research

Thrombectomy Outcomes in Acute Ischemic Stroke due to Middle Cerebral Artery M2 Occlusion with Stent-Retriever, Aspiration, and MERCI: Multi-Center Experience (P5.251)
Conclusions:Thrombectomy for AIS patients with MCA M2 ELVO with Stent-retriever appears to be feasible with a significantly higher rate of recanalization, lower sICH rate, and favorable 90-day mRS when compared to Aspiration and MERCI.Disclosure: Dr. Atchaneeyasakul has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Yavagal has received personal compensation for activities with Medtronic and Guidepoint as a consultant. Dr. Bouslama has nothing to disclose. Dr. Haussen has nothing to disclose. Dr. Kenmuir has nothing to disclose. Dr. Jadhav has nothing to disclose. Dr. Jovin has received personal compensation f...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Atchaneeyasakul, K., Malik, A., Yavagal, D., Bouslama, M., Haussen, D., Kenmuir, C., Jadhav, A., Jovin, T., Nogueira, R. Tags: Acute Cerebrovascular Interventional Therapies Source Type: research

Local Experience with a new retrievable stent (ERIC) in academic Center (P5.269)
Conclusions:In this study, the use of new ERIC retrieval device was technically feasible, safe, and effective in acute ischemic stroke with large-vessel occlusionDisclosure: Dr. Alshaer has nothing to disclose. Dr. Alturkustani has nothing to disclose. Dr. Khoja has nothing to disclose. Dr. Almekhlafi has nothing to disclose. Dr. Ayoub has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: AlShaer, D., Alturkustani, A., Khoja, A., Almekhlafi, M., Ayoub, O. Tags: Acute Cerebrovascular Interventional Therapies Source Type: research

Association between Leucocyte Count and Perihematomal Edema Growth After Primary Intracerebral Hemorrhage (N8.001)
Conclusions:Higher admission leucocyte count, particularly monocyte count, is associated with PHE growth. This suggests a potential role of inflammation in modulating PHE after ICH.Study Supported by: American Academy of Neurology and American Brain Foundation Clinical Research Training FellowshipDisclosure: Dr. Gusdon has nothing to disclose. Dr. Gialdini has nothing to disclose. Dr. Baradaran has nothing to disclose. Dr. Merkler has nothing to disclose. Dr. Iadecola has received personal compensation in an editorial capacity for the Journal of Neuroscience. Dr. Navi has nothing to disclose. Dr. Gupta has nothing to discl...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Gusdon, A., Gialdini, G., Baradaran, H., Merkler, A., Iadecola, C., Navi, B., Gupta, A., Kamel, H., Murthy, S. Tags: Neuroscience in the Clinic: Novel Therapeutic Targets in Critical Care Neurology: Intracerebral and Intraventricular Hemorrhage Source Type: research

Organovo CEO Murphy steps away, Crouch steps up | Personnel Moves – April 14, 2017
Organovo (PINK:ONVO) said earlier this week that Taylor Crouch has been appointed as CEO, replacing Keith Murphy who is stepping away from the company. The changes are slated to go into effect on April 21. Prior to being tapped for  the corner office, Crouch operated as CEO of investigative clinical research company eStudySite, the San Diego, Calif.-based company said. “I am extremely proud of the progress we have made in the last ten years achieving our vision for Organovo.  Our 3D bioprinted human tissues are a disruptive and game-changing technology.  Founding Organovo and guiding us to our leadership position...
Source: Mass Device - April 14, 2017 Category: Medical Equipment Authors: MassDevice staff Tags: Business/Financial News Active Implants AdvaMed Alphatec Holdings Inc. Anika Therapeutics Inc. Apollo Endosurgery Aurora Spine Baxter Biocorp Biogen Idec Biolase Technology Inc Bioventus LLC Bonesupport Clal Biotech Delcath Sys Source Type: news

Abstract 140: Effects of Smoking Co-Morbidities and Obesity on NonHemorrhagic Stroke Outcomes Session Title: Poster Session II
Conclusion: Smokers present with non-hemorrhagic stroke at a significantly younger age than non-smokers and die at much younger age during follow-up. While in our cohort smoking was not linked to other traditional risk factors for non-hemorrhagic stroke, it was associated with increased mortality in patients with decreased BMI, dyslipidemia, and with renal disease. "Protective" effect of increased BMI was not observed in smokers.
Source: Circulation: Cardiovascular Quality and Outcomes - March 31, 2017 Category: Cardiology Authors: Amato, D., Pieper, J., Ashamalla, M., Torosoff, M. Tags: Session Title: Poster Session II Source Type: research

Ischemic Stroke After Treatment of Intraprocedural Thrombosis During Stent-Assisted Coiling and Flow Diversion Brief Report
Conclusions—Current protocols for treatment of intraprocedural thrombosis associated with placement of intra-arterial devices were effective in preventing ischemic stroke in ≈80% of cases. Current smoking was the only independent predictor of ischemic stroke.
Source: Stroke - March 27, 2017 Category: Neurology Authors: Nimer Adeeb, Christoph J. Griessenauer, Justin M. Moore, Paul M. Foreman, Hussain Shallwani, Rouzbeh Motiei-Langroudi, Raghav Gupta, Carlos E. Baccin, Abdulrahman Alturki, Mark R. Harrigan, Adnan H. Siddiqui, Elad I. Levy, Christopher S. Ogilvy, Ajith J. Tags: Cerebral Aneurysm, Ischemic Stroke Brief Reports Source Type: research