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Condition: Ischemic Stroke
Drug: Phenobarbital

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Total 151 results found since Jan 2013.

Early Discontinuation of Phenobarbital After Acute Symptomatic Neonatal Seizures in the Term Newborn
In this study, we present a unified framework for phenobarbital discontinuation after resolution of acute symptomatic seizures in the setting of brain injury of the newborn.
Source: Neurology Clinical Practice - February 16, 2023 Category: Neurology Authors: Carrasco, M., Bonifacio, S. L., deVeber, G., Chau, V., on behalf of the Newborn Brain Society Guidelines, and Publications Committee Tags: EEG, Neonatal seizures Commentary Source Type: research

Efficacy of the anti-seizure medications in acute symptomatic neonatal seizures caused by stroke. A systematic review
CONCLUSIONS: Our review shows that the use of ASMs that act throughout a gabaergic mechanism are inadequate in controlling seizures secondary to neonatal stroke in full-term newborns. Very effective seems to be lidocaine and levetiracetam with an apparent safer profile in short and long term. Bumetanide shows promising results, but they need to be confirmed by phase 3 studies.PMID:36533757 | DOI:10.23750/abm.v93i6.13440
Source: Acta Bio-Medica : Atenei Parmensis - December 19, 2022 Category: General Medicine Authors: Vincenzo Sortino Andrea Pratic ò Silvia Marino Roberta Criscione Martino Ruggieri Francesco Pisani Raffaele Falsaperla Source Type: research