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Esmolol response in septic shock patients in relation to vascular waterfall phenomenon measured by critical closure pressure and mean systemic filling pressure: a prospective observational study
ConclusionPatients with septic shock whose heart rate is greater than 95 beats/min after hemodynamic optimization were treated with esmolol, which could effectively control heart rate and reduce CI, as well as improve Pcc and increase the difference between Pcc and Pmsf (known as “vascular waterfall” phenomenon), without affecting MAP, CVP, Pmsf and arteriovenous vascular resistance, and improve the balance of oxygen supply and demand in the body.
Source: Journal of Intensive Care - January 4, 2022 Category: Intensive Care Source Type: research

β1-blocker in sepsis
ConclusionAccumulating evidence is supporting the use of ultrashort-acting β1-blockers while larger randomized controlled trials to clarify the effect of ultrashort-acting β1-blockers are still warranted.
Source: Journal of Intensive Care - May 8, 2021 Category: Intensive Care Source Type: research

Passive leg raising test with minimally invasive monitoring: the way forward for guiding septic shock resuscitation?
ConclusionsThe passive leg raising maneuver in combination with real-time measurement of cardiac output changes is an easy-to-use, fast, relatively unbiased, and accurate bedside test to guide fluid management during septic shock.
Source: Journal of Intensive Care - June 8, 2017 Category: Intensive Care Source Type: research

Fluid responsiveness prediction using Vigileo FloTrac measured cardiac output changes during passive leg raise test
ConclusionsCO changes measured by the Vigileo ™ monitor using third-generation software during a PLR test predict fluid responsiveness in mixed medical and surgical patients withvasopressor-dependent circulatory shock.
Source: Journal of Intensive Care - October 5, 2016 Category: Intensive Care Source Type: research