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The Different Cardiovascular Outcomes Between Long-Term Efficacy of Hydrophilic and Lipophilic Statin Therapy in Both Asian Diabetic Sexes.
Conclusion: According to our long-term cohort study, hydrophilic statin use may be a better choice than lipophilic statin to reduce cardiovascular events in Asian diabetic patients. PMID: 31555067 [PubMed]
Source: Dose Response - June 30, 2019 Category: Drugs & Pharmacology Authors: Li SY, Chen HH, Lin CL, Yeh SY, Kao CH Tags: Dose Response Source Type: research

Hormesis and Endothelial Progenitor Cells
Dose Response. 2022 Feb 23;20(1):15593258211068625. doi: 10.1177/15593258211068625. eCollection 2022 Jan-Mar.ABSTRACTHormetic-biphasic dose response relationships are reported herein for human endothelial progenitor cells involving estradiol, nicotine, the anti-diabetic agent pioglitazone, resveratrol, and progesterone. In general, these studies demonstrate the capacity of these agents to enhance EPC proliferation and angiogenesis functional applications, having a focus on repairing endothelial tissue damage due to acute injury (e.g., stroke), as well as damage from chronic conditions (e.g., atherosclerosis) and normal agi...
Source: Dose Response - February 28, 2022 Category: Drugs & Pharmacology Authors: Edward J Calabrese Source Type: research