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Predicting Clinical Outcomes and Response to Thrombolysis in Acute Stroke Patients With Diabetes.
CONCLUSIONSStroke patients with diabetes have poorer outcomes compared with patients without diabetes, which is not explained by ICH. The iScore similarly predicts response to tPA between stroke patients with and without diabetes. PMID: 23359359 [PubMed - as supplied by publisher]
Source: Diabetes Care - January 28, 2013 Category: Endocrinology Authors: Nikneshan D, Raptis R, Pongmoragot J, Zhou L, Johnston SC, Saposnik G, on behalf of the Investigators of the Registry of the Canadian Stroke Network (RCSN) and the Stroke Outcomes Research Canada (SORCan) Working Group Tags: Diabetes Care Source Type: research

Association of glomerular filtration rate with outcomes of acute stroke in type 2 diabetic patients: results from the China National Stroke Registry.
CONCLUSIONSLow and high eGFRs (<45 ml/min/1.73m(2) or ≥120 ml/min/1.73m(2), respectively) are independent predictors of all-cause mortality and other poor outcomes after acute stroke in patients with type 2 diabetes. PMID: 24009297 [PubMed - as supplied by publisher]
Source: Diabetes Care - September 5, 2013 Category: Endocrinology Authors: Luo Y, Wang X, Wang Y, Wang C, Wang H, Wang D, Liu L, Jia Q, Liu G, Zhao X, Wang Y, on behalf of the CNSR investigators Tags: Diabetes Care Source Type: research

Incidence of Stroke According to Presence of Diabetic Nephropathy and Severe Diabetic Retinopathy in Patients With Type 1 Diabetes.
CONCLUSIONSThe presence of SDR and DN, independently, increases the risk of stroke, cerebral infarction, and cerebral hemorrhage in patients with type 1 diabetes. PMID: 24101700 [PubMed - as supplied by publisher]
Source: Diabetes Care - October 7, 2013 Category: Endocrinology Authors: Hägg S, Thorn LM, Putaala J, Liebkind R, Harjutsalo V, Forsblom CM, Gordin D, Tatlisumak T, Groop PH, on behalf of the FinnDiane Study Group Tags: Diabetes Care Source Type: research

Mediterranean Diet Reduces the Adverse Effect of the TCF7L2-rs7903146 Polymorphism on Cardiovascular Risk Factors and Stroke Incidence: A randomized controlled trial in a high-cardiovascular-risk population.
CONCLUSIONSOur novel results suggest that MedDiet may not only reduce increased fasting glucose and lipids in TT individuals, but also stroke incidence. PMID: 23942586 [PubMed - as supplied by publisher]
Source: Diabetes Care - August 13, 2013 Category: Endocrinology Authors: Corella D, Carrasco P, Sorlí JV, Estruch R, Rico-Sanz J, Martínez-González MA, Salas-Salvadó J, Covas MI, Coltell O, Arós F, Lapetra J, Serra-Majem L, Ruíz-Guiterrez V, Warnberg J, Fiol M, Pintó X, Ortega-Azorín C, Muñoz MA, Martínez JA, Gómez- Tags: Diabetes Care Source Type: research

Triglyceride and HDL-C Dyslipidemia and Risks of Coronary Heart Disease and Ischemic Stroke by Glycemic Dysregulation Status: The Strong Heart Study
CONCLUSIONS Adults with both high TG and low HDL-C, particularly those with diabetes, have increased risks of incident CHD and stroke. In particular, those with an LDL-C level ≥130 mg/dL may have an increased risk of incident stroke.
Source: Diabetes Care - March 20, 2017 Category: Endocrinology Authors: Lee, J. S.; Chang, P.-Y.; Zhang, Y.; Kizer, J. R.; Best, L. G.; Howard, B. V. Tags: Epidemiology/Health Services Research Source Type: research

Consequences of Comorbidity of Elevated Stress and/or Depressive Symptoms and Incident Cardiovascular Outcomes in Diabetes: Results From the REasons for Geographic And Racial Differences in Stroke (REGARDS) Study
CONCLUSIONS Comorbid stress and/or depressive symptoms are common in individuals with diabetes and together are associated with progressively increased risks for adverse CV outcomes.
Source: Diabetes Care - December 22, 2015 Category: Endocrinology Authors: Cummings, D. M.; Kirian, K.; Howard, G.; Howard, V.; Yuan, Y.; Muntner, P.; Kissela, B.; Redmond, N.; Judd, S. E.; Safford, M. M. Tags: Epidemiology/Health Services Research Source Type: research

Neck circumference, carotid wall intima-media thickness, and incident stroke.
PMID: 23970728 [PubMed - in process]
Source: Diabetes Care - August 28, 2013 Category: Endocrinology Authors: Rosenquist KJ, Massaro JM, Pencina KM, D'Agostino RB, Beiser A, O'Connor GT, O'Donnell CJ, Wolf PA, Polak JF, Seshadri S, Fox CS Tags: Diabetes Care Source Type: research

Fasting Glucose Level and the Risk of Incident Atherosclerotic Cardiovascular Diseases.
CONCLUSIONSBoth low glucose level and impaired fasting glucose should be considered as predictors of risk for stroke and coronary heart disease. The fasting glucose level associated with the lowest cardiovascular risk may be in a narrow range. PMID: 23404299 [PubMed - as supplied by publisher]
Source: Diabetes Care - February 12, 2013 Category: Endocrinology Authors: Park C, Guallar E, Linton JA, Lee DC, Jang Y, Son DK, Han EJ, Baek SJ, Yun YD, Jee SH, Samet JM Tags: Diabetes Care Source Type: research

External Validation of the UKPDS Risk Engine in Incident Type 2 Diabetes: a need for new risk type 2 diabetes-specific risk equations.
ConclusionsThe UKPDS stroke equations showed calibration ranging from poor to moderate; however, the CHD equations showed poor calibration and considerably overestimated CHD risk. There is a need for revised risk equations in type 2 diabetes. PMID: 24089541 [PubMed - as supplied by publisher]
Source: Diabetes Care - October 2, 2013 Category: Endocrinology Authors: Bannister CA, Poole CD, Jenkins-Jones S, Morgan CL, Elwyn G, Spasic I, Currie CJ Tags: Diabetes Care Source Type: research

Pioglitazone Prevents Diabetes in Patients With Insulin Resistance and Cerebrovascular Disease
CONCLUSIONS Among patients with insulin resistance but without diabetes who had had a recent ischemic stroke or TIA, pioglitazone decreased the risk of diabetes while also reducing the risk of subsequent ischemic events. Pioglitazone is the first medication shown to prevent both progression to diabetes and major cardiovascular events as prespecified outcomes in a single trial.
Source: Diabetes Care - September 21, 2016 Category: Endocrinology Authors: Inzucchi, S. E.; Viscoli, C. M.; Young, L. H.; Furie, K. L.; Gorman, M.; Lovejoy, A. M.; Dagogo-Jack, S.; Ismail-Beigi, F.; Korytkowski, M. T.; Pratley, R. E.; Schwartz, G. G.; Kernan, W. N.; for the IRIS Trial Investigators Tags: Clinical Care/Education/Nutrition/Psychosocial Research Source Type: research

Predicting Macro- and Microvascular Complications in Type 2 Diabetes: The Japan Diabetes Complications Study/the Japanese Elderly Diabetes Intervention Trial risk engine.
CONCLUSIONSThe risk engine accurately predicts macro- and microvascular complications and would provide helpful information in risk classification and health economic simulations. PMID: 23404305 [PubMed - as supplied by publisher]
Source: Diabetes Care - February 12, 2013 Category: Endocrinology Authors: Tanaka S, Tanaka S, Iimuro S, Yamashita H, Katayama S, Akanuma Y, Yamada N, Araki A, Ito H, Sone H, Ohashi Y, for the Japan Diabetes Complications Study Group, the Japanese Elderly Diabetes Intervention Trial Group Tags: Diabetes Care Source Type: research

Diabetes and end-stage renal disease synergistically contribute to increased incidence of cardiovascular events: A nation-wide follow-up study during 1998-2009.
ConclusionsDiabetes and ESRD synergistically increase risks of CV events. Proactive screening and control for diabetes in patients with ESRD should be built into our daily practice. PMID: 23920086 [PubMed - as supplied by publisher]
Source: Diabetes Care - August 6, 2013 Category: Endocrinology Authors: Chang YT, Wu JL, Hsu CC, Wang JD, Sung JM Tags: Diabetes Care Source Type: research

Associations Between Prediabetes, by Three Different Diagnostic Criteria, and Incident CVD Differ in South Asians and Europeans
CONCLUSIONS Associations between prediabetes and CVD differed by prediabetes diagnostic criterion, type of CVD, and ethnicity, with associations being present for overall CVD in Europeans but not South Asians. Substantiation of these findings and investigation of potential explanations are required.
Source: Diabetes Care - November 24, 2015 Category: Endocrinology Authors: Eastwood, S. V.; Tillin, T.; Sattar, N.; Forouhi, N. G.; Hughes, A. D.; Chaturvedi, N. Tags: Epidemiology/Health Services Research Source Type: research

Cardiovascular Mortality in Patients With Type 2 Diabetes and Recent Acute Coronary Syndromes From the EXAMINE Trial
CONCLUSIONS In patients with type 2 diabetes and a recent ACS, the risk of CV death was higher after a postrandomization, nonfatal CV event, particularly heart failure, compared with those who did not experience a CV event. The risk of CV death was similar between alogliptin and placebo.
Source: Diabetes Care - June 20, 2016 Category: Endocrinology Authors: White, W. B.; Kupfer, S.; Zannad, F.; Mehta, C. R.; Wilson, C. A.; Lei, L.; Bakris, G. L.; Nissen, S. E.; Cushman, W. C.; Heller, S. R.; Bergenstal, R. M.; Fleck, P. R.; Cannon, C. P.; for the EXAMINE Investigators Tags: Cardiovascular and Metabolic Risk Source Type: research

HbA1c and the Risks for All-Cause and Cardiovascular Mortality in the General Japanese Population: NIPPON DATA90.
CONCLUSIONSHigh HbA1c levels were associated with increased risk for all-cause mortality and death from CVD, coronary heart disease, and cerebral infarction in general East Asian populations, as in Western populations. PMID: 23877989 [PubMed - as supplied by publisher]
Source: Diabetes Care - July 22, 2013 Category: Endocrinology Authors: Sakurai M, Saitoh S, Miura K, Nakagawa H, Ohnishi H, Akasaka H, Kadota A, Kita Y, Hayakawa T, Ohkubo T, Okayama A, Okamura T, Ueshima H, for the NIPPON DATA90 Research Group Tags: Diabetes Care Source Type: research

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