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Condition: Motor Neurone Disease
Drug: Fortamet
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Total 6 results found since Jan 2013.
Highlighting the protective or degenerative role of AMPK activators in dementia experimental models
CNS Neurol Disord Drug Targets. 2021 May 26. doi: 10.2174/1871527320666210526160214. Online ahead of print.ABSTRACTAMP-activated protein kinase (AMPK) is a serine/threonine kinase and a driving or deterrent factor in the development of neurodegenerative diseases and dementia. AMPK affects intracellular proteins like the mammalian target of rapamycin (mTOR). Peroxisome proliferator-activated receptor-γ coactivator 1-α (among others) contributes to a wide range of intracellular activities based on its downstream molecules such as energy balancing (ATP synthesis), extracellular inflammation, cell growth, and neuronal cell d...
Source: CNS and Neurological Disorders Drug Targets - May 27, 2021 Category: Drugs & Pharmacology Authors: Marjan Nikbakhtzadeh Fatemeh Shaerzadeh Ghorbangol Ashabi Source Type: research
