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Systemic lupus erythematosus associated with development of macrophage activation syndrome and disseminated aspergillosis
CONCLUSIONS: Four features of this case merit discussion, including the: 1) infrequent association of SLE with MAS; 2) short interval between SLE diagnosis and critical illness; 3) manifestation of fungal tracheobronchitis with airway obstruction; and 4) lack of response to antifungal treatment while receiving ECMO.PMID:37349668 | DOI:10.1007/s12630-023-02506-2
Source: Canadian Journal of Anaesthesia - June 22, 2023 Category: Anesthesiology Authors: Vorakamol Phoophiboon Paula Brown Karen E A Burns Source Type: research

Intravenous Thrombolysis in Posterior Circulation Stroke
Conclusions: Up to date, no data about PCIS and IVT are available from RTCs. Based on limited results from retrospective clinical studies and case series, IVT is safer for use in PCIS than in ACIS. Patients with brainstem ischemia, vertebral artery occlusion, and absence of basilar or posterior cerebral artery occlusion could be considered for treatment with IVT even in borderline cases. Time to IVT in PCIS seems to be a less crucial factor than in ACIS. IVT for PCIS may be beneficial even after 4.5 h from symptom onset. Introduction History of Intravenous Thrombolysis—The Most Relevant Studies Intravenous...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

Different patients, different outcomes: A case ‐control study of spontaneous coronary artery dissection versus acute coronary syndrome
ConclusionSCAD affects young females with a paucity of cardiovascular risk factors. The major risk factor for SCAD was a history of anxiety, depression, or neuropsychiatric illness. A conservative approach to SCAD revascularization led to similar MACCE when compared to ACS controls undergoing guideline revascularization at 12 months.
Source: Journal of Interventional Cardiology - September 20, 2017 Category: Cardiology Authors: Heath Adams, Elizabeth Paratz, Jithendra Somaratne, Jamie Layland, Andrew Burns, Sonny Palmer, Andrew MacIsaac, Robert Whitbourn Tags: ORIGINAL INVESTIGATION Source Type: research

Acute Stroke Due to High Voltage Electrocution (P4.347)
We present a case of acute stroke due to high voltage electrocution. Case presentation 38 year old white male accidently grabbed a live wire in the field and got electrocuted. He sustained 2nd degree electric burns at the entry wound in his right palm with a small exist wound in the right foot. On admission, he was stable with total amnesia of the incident event. He had no major medical, psychiatric or substance abuse problems. He remained confused in the hospital with expressive aphasia. Repeat CT scan of the head showed multiple hypo density in both frontal and left partial region. MRI confirmed the presence of acute isc...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Kokatnur, L., Khan, I., Chernyshev, O., Rudrappa, M. Tags: Cerebrovascular Case Reports Source Type: research

Amyloid Beta Related Angiitis in the Setting of Anticoagulation (P2.256)
Conclusion: ABRA is a rare, but treatable cause of rapid cognitive decline. Early recognition of such a rare complication of CAA can improve outcomes through offering proper immunosuppressive treatment in a timely manner. The role of amyloid PET scan as a supportive diagnostic tool for CAA and ABRA is still to be defined.Disclosure: Dr. Costa has nothing to disclose. Dr. Albadareen has nothing to disclose. Dr. Sundararajan has nothing to disclose. Dr. Burns has received research support from Janssen, Wyeth, Pfizer, Danone, Baxter, and Lilly/Avid Radiopharmaceuticals.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Costa, C., Albadareen, R., Sundararajan, J., Burns, J. Tags: Cerebrovascular Disease and Interventional Neurology: Genetics and Stroke Source Type: research

Mechanical thrombectomy with the Solitaire stent: is there a learning curve in achieving rapid recanalization times?
Conclusions There is a learning curve involved in the efficient use of the Solitaire stent in endovascular acute stroke therapy. Along with improvements in patient transfer to angiography and improved efficiency with intracranial access, mastering this device contributed significantly towards reducing recanalization times.
Source: Journal of NeuroInterventional Surgery - October 7, 2014 Category: Neurosurgery Authors: Eesa, M., Burns, P. A., Almekhlafi, M. A., Menon, B. K., Wong, J. H., Mitha, A., Morrish, W., Demchuk, A. M., Goyal, M. Tags: Ischemic stroke Source Type: research