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Source: Circulation
Condition: Heart Disease

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Total 127 results found since Jan 2013.

Causal Associations of Adiposity and Body Fat Distribution with Coronary Heart Disease, Stroke Subtypes and Type 2 Diabetes: A Mendelian Randomization Analysis.
Conclusions -Both general and central adiposity have causal effects on CHD and T2D. Central adiposity may have a stronger effect on stroke risk. Future estimates of the burden of adiposity on health should include measures of central and general adiposity. PMID: 28500271 [PubMed - as supplied by publisher]
Source: Circulation - May 12, 2017 Category: Cardiology Authors: Dale C, Fatemifar G, Palmer T, White J, Prieto-Merino D, Zabaneh D, Engmann JEL, Shah T, Wong A, Warren HR, McLachlan S, Trompet S, Moldovan M, Morris RW, Sofat R, Kumari M, Hyppönen E, Jefferis BJ, Gaunt TR, Ben-Shlomo Y, Zhou A, Gentry-Maharaj A, Ryan Tags: Circulation Source Type: research

Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Scientific Statement for Health Professionals From the American Heart Association.
CONCLUSIONS: These recommendations provide updated and best evidence-based guidance to healthcare providers who diagnose and manage Kawasaki disease, but clinical decision making should be individualized to specific patient circumstances. PMID: 28356445 [PubMed - as supplied by publisher]
Source: Circulation - March 29, 2017 Category: Cardiology Authors: McCrindle BW, Rowley AH, Newburger JW, Burns JC, Bolger AF, Gewitz M, Baker AL, Jackson MA, Takahashi M, Shah PB, Kobayashi T, Wu MH, Saji TT, Pahl E, American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee of the Council Tags: Circulation Source Type: research

Correction to: Heart Disease and Stroke Statistics-2017 Update: A Report From the American Heart Association.
Authors: PMID: 28264899 [PubMed - in process]
Source: Circulation - March 6, 2017 Category: Cardiology Tags: Circulation Source Type: research

Anti-M üllerian Hormone Trajectories Are Associated With Cardiovascular Disease in Women: Results From the Doetinchem Cohort Study.
CONCLUSIONS: These results indicate that AMH trajectories in women are independently associated with CVD risk. Therefore, we postulate that the decline of circulating AMH levels may be part of the pathophysiology of the increased cardiovascular risk of earlier menopause. Confirmation of this association and elucidation of its underlying mechanisms are needed to place these results in a clinical perspective. PMID: 28153992 [PubMed - in process]
Source: Circulation - February 6, 2017 Category: Cardiology Authors: de Kat AC, Verschuren WM, Eijkemans MJ, Broekmans FJ, van der Schouw YT Tags: Circulation Source Type: research

The American Heart Association's New Institute for  Precision Cardiovascular Medicine.
The American Heart Association's New Institute for Precision Cardiovascular Medicine. Circulation. 2016 Nov 22;: Authors: Houser SR Abstract "One size does not fit all." These 6 simple words represent the fundamental concept driving an unprecedented initiative of the American Heart Association, the Institute for Precision Cardiovascular Medicine. In the field of heart disease and stroke research, we have seen enormous knowledge advances in recent decades, all of which have led to breakthroughs in our ability to treat and prevent these illnesses. We celebrate these advances because they are allowing u...
Source: Circulation - November 21, 2016 Category: Cardiology Authors: Houser SR Tags: Circulation Source Type: research

Clinical Outcomes in 3343 Children and Adults with Rheumatic Heart Disease from 14 Low and Middle Income Countries: 2-Year Follow-up of the Global Rheumatic Heart Disease Registry (the REMEDY study).
CONCLUSIONS: -Patients with clinical RHD have high mortality and morbidity despite being young; those from low and lower-middle income countries had a poorer prognosis associated with advanced disease and low education. Programs focused on early detection and treatment of clinical RHD are required to improve outcomes. PMID: 27702773 [PubMed - as supplied by publisher]
Source: Circulation - October 3, 2016 Category: Cardiology Authors: Zühlke L, Karthikeyan G, Engel ME, Rangarajan S, Mackie P, Cupido B, Mauff K, Islam S, Daniels R, Francis V, Ogendo S, Gitura B, Mondo C, Okello E, Lwabi P, Al-Kebsi MM, Hugo-Hamman C, Sheta SS, Haileamlak A, Daniel W, Goshu DY, Abdissa SG, Desta AG, Sha Tags: Circulation Source Type: research

Comparison of Dabigatran versus Warfarin in Patients with Atrial Fibrillation and Valvular Heart Disease: The RE-LY Trial.
CONCLUSIONS: -The presence of any VHD did not influence the comparison of dabigatran with warfarin. Clinical Trial Registration-URL: http://clinicaltrials.gov. Unique Identifier: NCT00262600. PMID: 27496855 [PubMed - as supplied by publisher]
Source: Circulation - August 4, 2016 Category: Cardiology Authors: Ezekowitz MD, Nagarakanti R, Noack H, Brueckmann M, Litherland C, Jacobs M, Clemens A, Reilly PA, Connolly SJ, Yusuf S, Wallentin L Tags: Circulation Source Type: research

Atherothrombotic Risk Stratification and the Efficacy and Safety of Vorapaxar in Patients with Stable Ischemic Heart Disease and Prior Myocardial Infarction.
CONCLUSIONS: -Stratification of baseline atherothrombotic risk can assist with therapeutic decision-making regarding vorapaxar use for secondary prevention after MI. Clinical Trial Registration-http://www.clinicaltrials.gov; NCT00526474. PMID: 27440003 [PubMed - as supplied by publisher]
Source: Circulation - July 19, 2016 Category: Cardiology Authors: Bohula EA, Bonaca MP, Braunwald E, Aylward PE, Corbalan R, De Ferrari GM, He P, Lewis BS, Merlini PA, Murphy SA, Sabatine MS, Scirica BM, Morrow DA Tags: Circulation Source Type: research

Long-Term Risk of Atherosclerotic Cardiovascular Disease in US Adults With the Familial Hypercholesterolemia Phenotype.
CONCLUSIONS: In the general US population, the long-term ASCVD burden related to phenotypic FH, defined by low-density lipoprotein cholesterol ≥190 mg/dL, is likely substantial. Our finding of CHD risk acceleration may aid efforts in risk communication. PMID: 27358432 [PubMed - in process]
Source: Circulation - July 2, 2016 Category: Cardiology Authors: Perak AM, Ning H, de Ferranti SD, Gooding HC, Wilkins JT, Lloyd-Jones DM Tags: Circulation Source Type: research

Endemic Cardiovascular Diseases of the Poorest Billion.
Abstract The poorest billion people are distributed throughout the world, though most are concentrated in rural sub-Saharan Africa and South Asia. Cardiovascular disease (CVD) data can be sparse in low- and middle-income countries beyond urban centers. Despite this urban bias, CVD registries from the poorest countries have long revealed a predominance of nonatherosclerotic stroke, hypertensive heart disease, nonischemic and Chagas cardiomyopathies, rheumatic heart disease, and congenital heart anomalies, among others. Ischemic heart disease has been relatively uncommon. Here, we summarize what is known about the e...
Source: Circulation - June 13, 2016 Category: Cardiology Authors: Kwan GF, Mayosi BM, Mocumbi AO, Miranda JJ, Ezzati M, Jain Y, Robles G, Benjamin EJ, Subramanian SV, Bukhman G Tags: Circulation Source Type: research

Low Systolic Blood Pressure and Vascular Mortality Among Over One Million Korean Adults.
CONCLUSIONS: -J-curve associations exist between SBP and vascular mortality, which reach a nadir at around 100 mmHg. SBP of less than 90 mmHg may portend death from vascular disease, particularly from ischemic heart disease. PMID: 27143683 [PubMed - as supplied by publisher]
Source: Circulation - April 26, 2016 Category: Cardiology Authors: Yi SW, Mok Y, Ohrr H, Yi JJ, Yun YD, Park J, Jee SH Tags: Circulation Source Type: research

Cardiovascular Diseases in India: Current Epidemiology and Future Directions.
Abstract Cardiovascular diseases (CVDs) have now become the leading cause of mortality in India. A quarter of all mortality is attributable to CVD. Ischemic heart disease and stroke are the predominant causes and are responsible for >80% of CVD deaths. The Global Burden of Disease study estimate of age-standardized CVD death rate of 272 per 100 000 population in India is higher than the global average of 235 per 100 000 population. Some aspects of the CVD epidemic in India are particular causes of concern, including its accelerated buildup, the early age of disease onset in the population, and the high case...
Source: Circulation - April 18, 2016 Category: Cardiology Authors: Prabhakaran D, Jeemon P, Roy A Tags: Circulation Source Type: research

Global Electrical Heterogeneity Risk Score for Prediction of Sudden Cardiac Death in the General Population: The Atherosclerosis Risk in Communities (ARIC) and Cardiovascular Health (CHS) Studies.
CONCLUSIONS: -Abnormal electrophysiological substrate quantified by GEH parameters is independently associated with SCD in the general population. Addition of GEH parameters to clinical characteristics improves SCD risk prediction. PMID: 27081116 [PubMed - as supplied by publisher]
Source: Circulation - April 13, 2016 Category: Cardiology Authors: Waks JW, Sitlani CM, Soliman EZ, Kabir M, Ghafoori E, Biggs ML, Henrikson CA, Sotoodehnia N, Biering-Sørensen T, Agarwal SK, Siscovick DS, Post WS, Solomon SD, Buxton AE, Josephson ME, Tereshchenko LG Tags: Circulation Source Type: research

Response to Letter Regarding Article, "Southern Dietary Pattern is Associated With Hazard of Acute Coronary Heart Disease in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study".
PMID: 26903027 [PubMed - in process]
Source: Circulation - February 23, 2016 Category: Cardiology Authors: Shikany JM, Safford MM, Newby PK, Durant RW, Brown TM, Judd SE Tags: Circulation Source Type: research

Letter by Archer Regarding Article, "Southern Dietary Pattern is Associated With Hazard of Acute Coronary Heart Disease in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study".
PMID: 26903026 [PubMed - in process]
Source: Circulation - February 23, 2016 Category: Cardiology Authors: Archer E Tags: Circulation Source Type: research