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Exercise medicine and physical activity promotion: core curricula for US medical schools, residencies and sports medicine fellowships: developed by the American Medical Society for Sports Medicine and endorsed by the Canadian Academy of Sport and Exercise Medicine
Regular physical activity provides a variety of health benefits and is proven to treat and prevent several non-communicable diseases. Specifically, physical activity enhances muscular and osseous strength, improves cardiorespiratory fitness, and reduces the risk of hypertension, coronary heart disease, stroke, type 2 diabetes, mental health disorders, cognitive decline and several cancers. Despite these well-known benefits, physical activity promotion in clinical practice is underused due to insufficient training during medical education. Medical trainees in the USA receive relatively few hours of instruction in sports and...
Source: British Journal of Sports Medicine - March 17, 2022 Category: Sports Medicine Authors: Asif, I., Thornton, J. S., Carek, S., Miles, C., Nayak, M., Novak, M., Stovak, M., Zaremski, J. L., Drezner, J. Tags: Editor's choice, BJSM Consensus statement Source Type: research

Physical inactivity and non-communicable disease burden in low-income, middle-income and high-income countries
Conclusion The global burden associated with physical inactivity is substantial. The relative burden is greatest in high-income countries; however, the greatest number of people (absolute burden) affected by physical inactivity are living in middle-income countries given the size of their populations.
Source: British Journal of Sports Medicine - January 3, 2022 Category: Sports Medicine Authors: Katzmarzyk, P. T., Friedenreich, C., Shiroma, E. J., Lee, I.-M. Tags: Editor's choice, Press releases, BJSM Original research Source Type: research

Effect of bariatric surgery versus medical therapy on long-term cardiovascular risk in low BMI Chinese patients with type 2 diabetes: a propensity score-matched analysis
CONCLUSION: Bariatric surgery in patients with T2D and low BMI conferred a lower calculated risk of CVD compared with medical therapy over 5 years of follow-up.PMID:34969592 | DOI:10.1016/j.soard.2021.11.019
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - December 31, 2021 Category: Surgery Authors: Zhigang Ke Xunmei Zhou Fang Sun Fan Li Weidong Tong Zhiming Zhu Source Type: research

FDA Approves Two New Indications for XARELTO ® (rivaroxaban) to Help Prevent and Treat Blood Clots in Pediatric Patients
RARITAN, NJ, Dec. 20, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that the U.S. Food and Drug Administration (FDA) has approved two pediatric indications for XARELTO® (rivaroxaban): the treatment of venous thromboembolism (VTE, or blood clots) and reduction in the risk of recurrent VTE in patients from birth to less than 18 years after at least five days of initial parenteral (injected or intravenous) anticoagulant treatment; and thromboprophylaxis (prevention of blood clots and blood-clot related events) in children aged two years and older with congenital heart disease who have...
Source: Johnson and Johnson - December 21, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Milk intake and incident stroke and coronary heart disease in populations of European descent: A Mendelian Randomization study
Br J Nutr. 2021 Oct 21:1-25. doi: 10.1017/S0007114521004244. Online ahead of print.ABSTRACTHigher milk intake has been associated with a lower stroke risk, but not with risk of coronary heart disease (CHD). Residual confounding or reverse causation cannot be excluded. Therefore, we estimated the causal association of milk consumption with stroke and CHD risk through instrumental variable (IV) and gene-outcome analyses. IV analysis included 29,328 participants (4,611 stroke; 9,828 CHD) of the EPIC-CVD (8 European countries) and EPIC-NL case-cohort studies. rs4988235, a lactase persistence (LP) single nucleotide polymorphism...
Source: The British Journal of Nutrition - October 21, 2021 Category: Nutrition Authors: L E T Vissers I Sluijs S Burgess N G Forouhi H Freisling F Imamura T K Nilsson F Renstr öm E Weiderpass K Aleksandrova C C Dahm A Perez-Cornago M B Schulze T Y N Tong D Aune C Bonet J M A Boer H Boeing M D Chirlaque M I Conchi L Imaz S J äger V Krogh C Source Type: research

Rheumatoid Arthritis and Cardio-Cerebrovascular Disease: A Mendelian Randomization Study
Significant genetic association exists between rheumatoid arthritis (RA) and cardiovascular disease. The associated mechanisms include common inflammatory mediators, changes in lipoprotein composition and function, immune responses, etc. However, the causality of RA and vascular/heart problems remains unknown. Herein, we performed Mendelian randomization (MR) analysis using a large-scale RA genome-wide association study (GWAS) dataset (462,933 cases and 457,732 controls) and six cardio-cerebrovascular disease GWAS datasets, including age angina (461,880 cases and 447,052 controls), hypertension (461,880 cases and 337,653 c...
Source: Frontiers in Genetics - October 21, 2021 Category: Genetics & Stem Cells Source Type: research

Associations of ophthalmic and systemic conditions with incident dementia in the UK Biobank
CONCLUSIONS: AMD, cataract and DRED but not glaucoma are associated with an increased risk of dementia. Individuals with both ophthalmic and systemic conditions are at higher risk of dementia compared with those with an ophthalmic or systemic condition only.PMID:34518160 | DOI:10.1136/bjophthalmol-2021-319508
Source: The British Journal of Ophthalmology - September 14, 2021 Category: Opthalmology Authors: Xianwen Shang Zhuoting Zhu Yu Huang Xueli Zhang Wei Wang Danli Shi Yu Jiang Xiaohong Yang Mingguang He Source Type: research

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