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Heart attacks and the efficacy of polypills – a hard pill to swallow? | Letters
Dr Peter Trewby questions the risk-reduction figures of the Iran study andOliver Lepen says the focus must be on preventing disease, not medicationYour headline (Single polypill reduces risk of heart attacks and strokes, study finds, 23 August) should really have been tempered by quoting the absolute rather than the relative risk-reduction figures.The 34% reduction in major cardiac events you quote is calculated from “on the ground” reduction in events from 8.8% over five years in those not on the polypill to 5.9% in those receiving it – that is a 2.9% chance of benefit over five years to the individual and with no e...
Source: Guardian Unlimited Science - August 25, 2019 Category: Science Authors: Letters Tags: Drugs Health Society Science Heart disease Heart attack Stroke Medical research Medicine Pharmaceuticals industry Source Type: news

Single polypill reduces risk of heart attacks and strokes, study finds
Large trial held in Iran of inexpensive medication combining four common drugsA cheap, single pill taken once a day that combines four common drugs is safe and reduces the risk of events such as heart attacks, strokes and sudden death in people over the age of 50, research has found.The study, the first large-scale trial to date, looked at the effectiveness of a so-called polypill – a four-in-one therapy containing drugs to lower cholesterol and blood pressure that was first proposed more than 15 years ago. The researchers found those taking the polypill had a more than 30% lower risk of serious heart problems than those...
Source: Guardian Unlimited Science - August 23, 2019 Category: Science Authors: Nicola Davis Tags: Medical research Heart disease Heart attack Stroke Health Pharmaceuticals industry Drugs Science Iran Source Type: news