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Source: Herpes
Condition: Encephalitis

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Total 20 results found since Jan 2013.

GLUTAMATE RECEPTOR ANTIBODIES IN NEUROLOGICAL DISEASES: Anti-AMPA-GluR3 antibodies, Anti-NMDA-NR1 antibodies, Anti-NMDA-NR2A/B antibodies, Anti-mGluR1 antibodies or Anti-mGluR5 antibodies are present in subpopulations of patients with either: Epilepsy, Encephalitis, Cerebellar Ataxia, Systemic Lupus Erythematosus (SLE) and Neuropsychiatric SLE, Sjogren's syndrome, Schizophrenia, Mania or Stroke. These autoimmune anti-glutamate receptor antibodies can bind neurons in few brain regions, activate glutamate receptors, decrease glutamate receptor's expression, impair glutamate-induced signaling and function, activate Blood Brain Barrier endothelial cells, kill neurons, damage the brain, induce behavioral/psychiatric/cognitive abnormalities and Ataxia in animal models, and can be removed or silenced in some patients by immunotherapy.
Abstract Glutamate is the major excitatory neurotransmitter of the Central Nervous System (CNS), and it is crucially needed for numerous key neuronal functions. Yet, excess glutamate causes massive neuronal death and brain damage by excitotoxicity-detrimental over activation of glutamate receptors. Glutamate-mediated excitotoxicity is the main pathological process taking place in many types of acute and chronic CNS diseases and injuries. In recent years, it became clear that not only excess glutamate can cause massive brain damage, but that several types of anti-glutamate receptor antibodies, that are present in ...
Source: Herpes - August 1, 2014 Category: Infectious Diseases Authors: Levite M Tags: J Neural Transm Source Type: research

Herpes simplex virus encephalitis mimicking acute ischemic stroke
CONCLUSION: HSV infections may mimic stroke and therefore should be included in the differential diagnosis of atypical acute nervous conditions. In neurological events of acute nature, especially in febrile patients whose brain imaging is suspicious or inconclusive, the eventuality of a herpetic encephalitis should be kept in mind. This will lead to a prompt antiviral therapy and to a favorable outcome.PMID:36895212 | PMC:PMC9990771 | DOI:10.25259/SNI_1123_2022
Source: Herpes - March 10, 2023 Category: Infectious Diseases Authors: Ermir Ro çi Stela Dodaj Gentian Vyshka Source Type: research

Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome mimicking herpes simplex encephalitis: A case report
Radiol Case Rep. 2022 May 8;17(7):2428-2431. doi: 10.1016/j.radcr.2022.04.019. eCollection 2022 Jul.ABSTRACTMitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome presents with the features of herpes simplex encephalitis (HSE), which is rare and has been described in only a few case reports. Our case describes a 17-year-old female with no significant previous medical history presenting with an acute onset of fever, headache, and epilepsy, similar to HSE. Computed tomography of the brain showed bilateral basal ganglia calcification. Magnetic resonance imaging demonstrated gyriform...
Source: Herpes - May 23, 2022 Category: Infectious Diseases Authors: Wen-Gao Zeng Wan-Min Liao Jue Hu Su-Fen Chen Zhen Wang Source Type: research

Herpes Simplex Virus Meningoencephalitis Masquerading as Acute Stroke With Broca's Aphasia: A Case Report
This report highlights the importance of considering herpes encephalitis as a potential etiology in patients presenting with atypical neurological symptoms, even in the absence of typical radiological findings. Early diagnosis and appropriate management with acyclovir are crucial in improving outcomes in such cases.PMID:37476130 | PMC:PMC10354683 | DOI:10.7759/cureus.40618
Source: Herpes - July 21, 2023 Category: Infectious Diseases Authors: Gagandeep Singh Arora Don Phung Parneet Kaur Source Type: research

Periodic electroencephalographic discharges and epileptic spasms involve cortico-striatal-thalamic loops on Arterial Spin Labeling Magnetic Resonance Imaging
Brain Commun. 2022 Oct 6;4(5):fcac250. doi: 10.1093/braincomms/fcac250. eCollection 2022.ABSTRACTPeriodic discharges are a rare peculiar electroencephalogram pattern, occasionally associated with motor or other clinical manifestations, usually observed in critically ill patients. Their underlying pathophysiology remains poorly understood. Epileptic spasms in clusters and periodic discharges with motor manifestations share similar electroencephalogram pattern and some aetiologies of unfavourable prognosis such as subacute sclerosing panencephalitis or herpes encephalitis. Arterial spin labelling magnetic resonance imaging i...
Source: Herpes - November 3, 2022 Category: Infectious Diseases Authors: Monika Eisermann Ludovic Fillon Ana Saitovitch Jennifer Boisgontier Alice Vin çon-Leite Volodia Dangouloff-Ros Thomas Blauwblomme Marie Bourgeois Marie-Th érèse Dangles Delphine Coste-Zeitoun Patricia Vignolo-Diard M élodie Aubart Manoelle Kossorotoff Source Type: research

Stroke, covid-19 infection or herpes simplex encephalitis: a diagnostic dilemma
Ulster Med J. 2022 Jan;91(1):56-57. Epub 2022 Feb 11.NO ABSTRACTPMID:35169345 | PMC:PMC8835425
Source: Herpes - February 16, 2022 Category: Infectious Diseases Authors: Traynor R Shanahan B Walsh J Ryan A Pope G Source Type: research

Stroke, covid-19 infection or herpes simplex encephalitis: a diagnostic dilemma
Ulster Med J. 2022 Jan;91(1):56-57. Epub 2022 Feb 11.NO ABSTRACTPMID:35169345 | PMC:PMC8835425
Source: Herpes - February 16, 2022 Category: Infectious Diseases Authors: Traynor R Shanahan B Walsh J Ryan A Pope G Source Type: research

The Importance of CXCL1 in Physiology and Noncancerous Diseases of Bone, Bone Marrow, Muscle and the Nervous System
Int J Mol Sci. 2022 Apr 11;23(8):4205. doi: 10.3390/ijms23084205.ABSTRACTThis review describes the role of CXCL1, a chemokine crucial in inflammation as a chemoattractant for neutrophils, in physiology and in selected major non-cancer diseases. Due to the vast amount of available information, we focus on the role CXCL1 plays in the physiology of bones, bone marrow, muscle and the nervous system. For this reason, we describe its effects on hematopoietic stem cells, myoblasts, oligodendrocyte progenitors and osteoclast precursors. We also present the involvement of CXCL1 in diseases of selected tissues and organs including A...
Source: Herpes - April 23, 2022 Category: Infectious Diseases Authors: Jan Korbecki Magdalena G ąssowska-Dobrowolska Jerzy W ójcik Iwona Szatkowska Katarzyna Barczak Miko łaj Chlubek Irena Baranowska-Bosiacka Source Type: research

Herpes simplex encephalitis presenting as a stroke-like episode following a migraine attack: a case report
Rinsho Shinkeigaku. 2022 Jun 24. doi: 10.5692/clinicalneurol.cn-001745. Online ahead of print.ABSTRACTA 23-year-old woman, who had been suffering from migraine since primary school age, presented with left arm paralysis three days after one such migraine attack. On admission, brain MRI diffusion-weighted imaging (DWI) demonstrated high-signal-intensity lesions in the white matter of the right fronto-parietal lobe, and no abnormal lesions were evident in the limbic system. Although the patient had a fever of 38.7°C, the CSF cell count was not elevated. On the 4‍th day, the left arm paralysis worsened, with an increase in...
Source: Herpes - June 26, 2022 Category: Infectious Diseases Authors: Moeno Yamamoto Masaki Namekawa Masanori Ishikawa Hiroyuki Watanabe Mutshuo Oyake Nobuya Fujita Source Type: research

Erratum: Herpes simplex encephalitis presenting as a stroke-like episode following a migraine attack: a case report
Rinsho Shinkeigaku. 2022;62(7):594. doi: 10.5692/clinicalneurol.62_cn-001745e.NO ABSTRACTPMID:35908866 | DOI:10.5692/clinicalneurol.62_cn-001745e
Source: Herpes - July 31, 2022 Category: Infectious Diseases Source Type: research