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Incidence, prevalence and disability associated with neurological disorders in Italy between 1990 and 2019: an analysis based on the Global Burden of Disease Study 2019
ConclusionsThe increase in YLDs associated with neurological conditions is mostly due to population ageing and growth: nevertheless, lived disability and, as a consequence, impact on health systems has increased. Actions are needed to improve outcome and mitigate disability associated with neurological conditions, spanning among diagnosis, treatment, care pathways and workplace interventions.
Source: Journal of Neurology - September 8, 2021 Category: Neurology Source Type: research

Altered mental status in COVID-19
ConclusionIn patients with COVID-19, AMS on presentation to the ED is most frequently caused by metabolic encephalopathy (delirium). Seizures and cerebrovascular events contribute to a lesser degree; encephalitis appears rare.
Source: Journal of Neurology - June 3, 2021 Category: Neurology Source Type: research

Central and peripheral nervous system complications of COVID-19: a prospective tertiary center cohort with 3-month follow-up
ConclusionCNS  and PNS complications were common in hospitalized COVID-19 patients, particularly in the ICU, and often attributable to critical illness. When COVID-19 was the primary cause for neurological disease, no signs of viral neurotropism were detected, but laboratory changes suggested autoimmune-mediate d mechanisms.
Source: Journal of Neurology - January 13, 2021 Category: Neurology Source Type: research

Neurological involvement of coronavirus disease 2019: a systematic review
ConclusionsNeurological manifestations of COVID-19 are not rare, especially large vessel stroke, Guillain –Barre syndrome, and meningoencephalitis. Moving forward, further studies are needed to clarify the prevalence of the neurological complications of SARS-CoV-2 infection, investigate their biological backgrounds, and test treatment options. Physicians should be cautious not to overlook other neurol ogical diagnoses that can mimic COVID-19 during the pandemic.
Source: Journal of Neurology - June 18, 2020 Category: Neurology Source Type: research

Burden of herpes simplex virus encephalitis in the United States
AbstractHerpes simplex virus encephalitis (HSVE) is a disease of public health concern, but its burden on the healthcare of United States has not been adequately assessed recently. We aimed to define the incidence, complications and outcomes of HSVE in the recent decade by analyzing data from a nationally representative database. Healthcare Cost and Utilization Project databases were utilized to identify patients with primary discharge diagnosis of HSVE. Annual hospitalization rate was estimated and several preselected inpatient complications were identified. Regression analyses were used to identify mortality predictors. ...
Source: Journal of Neurology - May 17, 2017 Category: Neurology Source Type: research