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Source: Neurology
Condition: Aphasia

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Total 134 results found since Jan 2013.

Teaching NeuroImages: Susceptibility-weighted MRI: First clue to DAVF complicating sinovenous thrombosis
A 61-year-old man with factor V Leiden thrombophilia presented with hemorrhage and transverse sinus thrombosis (figure, A). Four years later, he developed worsening aphasia, new hemorrhage, and hemispheric edema (figure, B). Susceptibility-weighted imaging (SWI) showed bright signal in the straight sinus (figure, C). A dural arteriovenous fistula (DAVF) was diagnosed (figure, D). The brain edema improved (figure, E) and SWI sinus hyperintensity resolved after endovascular disconnection of the fistula (figure, F).
Source: Neurology - May 20, 2013 Category: Neurology Authors: Kalra, V. B., Malhotra, A., Matouk, C. C. Tags: MRI, All Cerebrovascular disease/Stroke, Arteriovenous malformation, Cerebral venous thrombosis RESIDENT AND FELLOW SECTION Source Type: research

Teaching NeuroImages: Treatment-resistant rapidly progressive amyloid {beta}-related angiitis
A 76-year-old woman presented with 1 month of progressive aphasia, headache, and subsequent right hemiparesis. Initial brain MRI showed a punctate infarct (figure 1, A and C). Susceptibility-weighted imaging was unremarkable. A repeat study 16 days later demonstrated bihemispheric infarcts with multifocal attenuation of intracranial vessels on magnetic resonance angiography (figure 1, B and D). CSF showed a lymphocytic pleocytosis (101 leukocytes/µL) and elevated protein (480 mg/dL). Brain biopsy showed granulomatous angiitis with amyloid deposition and fibrinoid necrosis surrounded by inflammatory cells (figure 2). ...
Source: Neurology - April 29, 2013 Category: Neurology Authors: Porter, M., Newey, C. R., Toth, G. Tags: MRI, Other cerebrovascular disease/ Stroke, Alzheimer's disease, Infarction RESIDENT AND FELLOW SECTION Source Type: research

Improved Naming after Excitatory Repetitive Deep Transcranial Magnetic Stimulation over the Right Homologous Broca's Region in Chronic Post-Stroke Aphasia (P03.156)
CONCLUSIONS: A single session of excitatory deep brain rTMS on the right inferior frontal gyrus with H-coil significantly improves naming in chronic aphasic post-stroke right-handed patients. This result suggests that the right hemisphere may play a positive, rather than detrimental role, in the recovery of aphasia occurring after a left-hemispheric stroke in right handed subjects.Disclosure: Dr. Chieffo has nothing to disclose. Dr. Ferrari has nothing to disclose. Dr. Battista has nothing to disclose. Dr. Nuara has nothing to disclose. Dr. Houdayer has nothing to disclose. Dr. Alemanno has nothing to disclose. Dr. Abutale...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Chieffo, R., Ferrari, F., Battista, P., Nuara, A., Houdayer, E., Alemanno, F., Abutalebi, J., Zangen, A., Comi, G., Cappa, S., Leocani, L. Tags: P03 Cerebrovascular Disease III Source Type: research

Primary Central Nervous System Vasculitis Triggered by Cytomegalovirus Encephalitis (P01.231)
CONCLUSIONS: Our case is the first reported case in the literature of proven CMV encephalitis triggering a subsequent non-infectious CNS vasculitis probably secondary to an autoimmune response. The absence of findings in the initial MRIs of the brain in spite of an intermittently symptomatic patient and the subsequent development of ischemic infarcts supports the theory of intermittent focal hypoperfusion, finally leading to infarction. The high clinical suspicion even with lack of clear evidence of the disease process and empirical treatment led to a successful clinical recovery.Disclosure: Dr. Rosales has nothing to disc...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Rosales, D., Garcia-Gracia, C., Salgado, E., Salanga, V. Tags: P01 Cerebrovascular Disease I Source Type: research

Post-Stroke Aphasia: Differences in White Matter Fractional Anisotropy between Recovered and Non-Recovered Patients (P03.161)
CONCLUSIONS: Greater left hemispheric damage to brain structures and decreased intrahemispheric connections in patients with aphasia are evident in the white matter FA differences between the groups. Group differences in corpus callosum FA also indicate possible reductions in interhemispheric connections in chronically aphasic patients. These group differences may underlie post-stroke recovery.Supported by: NS048281; HD068488.Disclosure: Dr. Allendorfer has nothing to disclose. Dr. Szaflarski has received personal compensation for activities with UCB Pharma. Dr. Szaflarski has received research support from NIH, AAN, Shor ...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Allendorfer, J., Szaflarski, J. Tags: P03 Cerebrovascular Disease III Source Type: research

Early Spontaneous Recanalization of Symptomatic Carotid Occlusion: When Should We Be Looking? (P01.238)
CONCLUSIONS: Spontaneous recanalization of an occluded carotid artery may occur in a subacute fashion. Clinical deterioration, even minor, should prompt an investigation into possible recanalization.Disclosure: Dr. Cutting has received personal compensation for activities with F1000. Dr. Conners has nothing to disclose. Dr. Prabhakaran has nothing to disclose. Dr. Song has received personal compensation in an editorial capacity for serving as Advocacy Editor for AAN.com.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Cutting, S., Conners, J., Prabhakaran, S., Song, S. Tags: P01 Cerebrovascular Disease I Source Type: research

Ultra Hyperacute MR Findings in Reperfusion Hemorrhage (P01.243)
CONCLUSIONS: The clinician should be aware that hypointense signal on GRE typically associated with hyperacute intracerebral hemorrhage may be absent if imaged very early.Disclosure: Dr. Samuels has nothing to disclose. Dr. Jhaveri has nothing to disclose. Dr. Conners has nothing to disclose. Dr. Cutting has received personal compensation for activities with F1000. Dr. Prabhakaran has nothing to disclose. Dr. Lee has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Samuels, J., Jhaveri, M., Conners, J., Cutting, S., Prabhakaran, S., Lee, V. Tags: P01 Cerebrovascular Disease I Source Type: research

Case Report: "Dystextia" as a Sole Manifestation of Expressive Aphasia in Acute Ischemic Stroke (P03.175)
CONCLUSIONS: Text messaging is a common practice of communication with >75 billion texts/month. Evaluation of "dystextia" may become a vital tool in determining language deficits in addition to the routine assessment. It also may help establish time of stroke symptom onset in patients who are in consideration for receiving acute stroke interventions as text messaging is always time/date stamped.Disclosure: Dr. Kaskar has nothing to disclose. Dr. Patel has nothing to disclose. Dr. Miller has nothing to disclose. Dr. Angus has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Kaskar, O., Patel, K., Miller, D., Angus, E. Tags: P03 Cerebrovascular Disease III Source Type: research

Are Thalamic Aphasia and Neglect Due to Cortical Hypoperfusion? (P01.004)
CONCLUSIONS: Isolated left thalamic infarcts can cause naming impairment (perhaps via diaschisis) without cortical hypoperfusion, irrespective of lesion volume. However, thalamic neglect (and comprehension impairments) may be largely due to cortical hypoperfusion.Supported by: R01 DC 05375 and R01 NS047691 and R01 DC03681.Disclosure: Dr. Schein has nothing to disclose. Dr. Sebastian has nothing to disclose. Dr. Hillis has received personal compensation in an editorial capacity for Behavioural Neurology. Dr. Hillis has received research support from Allon Pharmaceutical.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Schein, M., Sebastian, R., Hillis, A. Tags: P01 Behavioral Neurology: Attention and Executive Functions Source Type: research

Incidence and Types of Seizures in Acute - A Single Center Experience (P01.252)
CONCLUSIONS: This is one of the largest studies describing occurrence of seizures post stroke. Seizures occurred in 7.9 % of patients with stroke. Focal seizures were the most common type and MCA territory infarcts were more likely to be associated with seizures. PSS were more likely to occur in those with ischemic infarcts as compared to hemorrhagic infarcts.Disclosure: Dr. Mehndiratta has nothing to disclose. Dr. Mehndiratta has nothing to disclose. Dr. Kumar has nothing to disclose. Dr. Nayak has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Mehndiratta, M. M., Mehndiratta, P., Kumar, M., Nayak, R. Tags: P01 Cerebrovascular Disease I Source Type: research

Clinical Features and Management of Ischemic Stroke in Pakistan (P02.031)
CONCLUSIONS: Risk factors for stroke in Pakistan are similar to patients in North America. However the majority of patients are either unaware or have poor management of stroke risk factors. Efforts at risk factor management are important to reduce the burden of stroke in this population.Disclosure: Dr. Khan has nothing to disclose. Dr. Shuaib has nothing to disclose. Dr. Khatri has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Farooq has nothing to disclose. Dr. Mehboob has nothing to disclose. Dr. Khattak has nothing to disclose. Dr. Nazir has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Khan, H., Shuaib, U., Khatri, I., Malik, S., Farooq, U., Mehboob, N., Khattak, J., Nazir, R. Tags: P02 Cerebrovascular Disease II Source Type: research

SMART Syndrome (Stroke-Like Migraine Attacks after Radiation Therapy) in Adult and Pediatric Patients (P03.007)
CONCLUSIONS: SMART syndrome appears to be a reversible and recurrent long term complication of cranial irradiation. A review of the data indicates that age and gender may play a role in the development of the disease. Additionally, we postulate other mechanisms of SMART syndrome including possible genetic and hormonal influences.Disclosure: Dr. Armstrong has nothing to disclose. Dr. DiMario has received personal compensation for activities with E-Pocrates.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Armstrong, A., DiMario, F. Tags: P03 Child Neurology II Source Type: research

Herpes-Simplex Virus 2: A New Player in Cerebral Vasculitis (P03.259)
CONCLUSIONS: The spectrum of atypical CNS manifestations related to HSV is emerging. We report a case of cerebral vasculitis, which was masked by the initial presentation as thalamic hemorrhage and followed by an encephalitic syndrome and multifocal ischemic stroke. The work-up revealed HSV-2 as a new and treatable cause of infectious vasculitis.Supported by: JS is supported by a scientific fellowship from the European Federation of Neurological Societies.Disclosure: Dr. Sellner has nothing to disclose. Dr. Wunderlich has nothing to disclose. Dr. Förschler has nothing to disclose. Dr. Nadas has nothing to disclose. Dr...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Sellner, J., Wunderlich, S., Forschler, A., Nadas, K., Hemmer, B., Zepper, P. Tags: P03 Infections I Source Type: research

Is Intracranial Intra-Arterial Thrombolysis and Thrombectomy Expertise Necessary for Carotid Artery Stent Procedures in Contemporary Practice? (P02.046)
CONCLUSIONS: Although neurological deterioration following CAS can be infrequently seen, the rate and value of intra-arterial thrombolysis and thrombectomy for cerebral ischemic events is very low.Disclosure: Dr. Hartmann has nothing to disclose. Dr. Chaudhry has nothing to disclose. Dr. Allam has nothing to disclose. Dr. Chaudhry has nothing to disclose. Dr. ATACH Investigators has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Hartmann, A., Chaudhry, S., Allam, H., Seeman, E., Qureshi, A. Tags: P02 Cerebrovascular Disease II Source Type: research