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Increased depression risk among patients with chronic osteomyelitis
Inflammatory processes, which provoke alternations of neurotransmitter metabolism, neuroendocrine function, and neuroplasticity in the brain, might promote depression. In depression patients who do not exhibit risk factors, including hypertension, diabetes, coronary heart disease, stroke, Parkinson's disease and dementia, particularly in young people, inflammation is a likely risk factor for depression. We explored whether chronic osteomyelitis (COM), a chronic inflammatory disease, increases depression risk.
Source: Journal of Psychosomatic Research - September 14, 2014 Category: Psychiatry & Psychology Authors: Chun-Hung Tseng, Wei-Shih Huang, Chih-Hsin Muo, Yen-Jung Chang, Chia-Hung Kao Source Type: research

Increased risk of coronary heart disease in patients with chronic osteomyelitis: a population-based study in a cohort of 23 million
Conclusions This study demonstrates that COM is an independent risk factor for CHD, particularly in the younger population. Further studies are necessary to explore the underlying mechanisms linking COM and CHD.
Source: Heart - August 21, 2014 Category: Cardiology Authors: Hsiao, L.-C., Muo, C.-H., Chen, Y.-C., Chou, C.-Y., Tseng, C.-H., Chang, K.-C. Tags: Health policy, Drugs: cardiovascular system, Hypertension, Epidemiology, Metabolic disorders Coronary artery disease Source Type: research

Increased risk of ischaemic stroke amongst patients with chronic osteomyelitis: a population‐based cohort study in Taiwan
ConclusionsThis is the first report linking COM to an increased risk of developing stroke. Results suggest that COM is a significant stroke risk factor and call for closer attention to this group of patients for more rigorous stroke prevention, especially in the younger age group.
Source: European Journal of Neurology - March 1, 2014 Category: Neurology Authors: C.‐H. Tseng, J.‐H. Chen, C.‐H. Muo, Y.‐J. Chang, F.‐C. Sung, C. Y. Hsu Tags: Original Article Source Type: research