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Anti-platelet and anti-thrombotic effect of a traditional herbal medicine Kyung-Ok-Ko
Conclusions These findings suggest that KOK elicits remarkable anti-platelet and anti-thrombotic effects with less side effect of bleeding, and therefore, it may have a therapeutic potential for the prevention of platelet-associated cardiovascular diseases. Graphical abstract
Source: Journal of Ethnopharmacology - December 17, 2015 Category: Drugs & Pharmacology Source Type: research

Can Chinese Herbal Medicine Adjunctive Therapy Improve Outcomes of Senile Vascular Dementia? Systematic Review with Meta‐analysis of Clinical Trials
Many publications have reported the growing application of complementary and alternative medicine, particularly the use of Chinese herbal medicine (CHM) in combination with routine pharmacotherapy (RP) for senile vascular dementia (SVD), but its efficacy remains largely unexplored. The purpose of this study is to evaluate the efficacy of CHM adjunctive therapy (CHMAT), which is CHM combined with RP, in the treatment of SVD. Publications in seven electronic databases were searched extensively, and 27 trials with a total of 1961 patients were included for analysis. Compared with RP alone, CHMAT significantly increased the ef...
Source: Phytotherapy Research - October 6, 2015 Category: Biochemistry Authors: Lingfeng Zeng, Yuanping Zou, Lingshuo Kong, Ningsheng Wang, Qi Wang, Lu Wang, Ye Cao, Kezhu Wang, Yunbo Chen, Suiqing Mi, Wei Zhao, Haitao Wu, Shuyi Cheng, Weihua Xu, Weixiong Liang Tags: Review Source Type: research

The neuroprotective effect of a traditional herbal (kyung‐ok‐ko) on transient middle cerebral artery occlusion‐Induced ischemic rat brain
We examined whether KOK improves functional recovery and has a neuroprotective effect on infarction volume after transient middle cerebral artery occlusion (MCAO). KOK (50, 100, and 200 mg/kg) was administered orally following reperfusion and twice per day for 14 days post‐MCAO. Infarction volume was measured using 2% 2‐3‐5 triphenylterazolium (TTC) staining at 14 days post‐MCAO and alteration in regional cerebral blood flow (rCBF) after KOK treatment was monitored. Functional improvement was evaluated using adhesive removal and treadmill tests at 1, 7, and 14 days post‐MCAO. Also, apoptotic cell death was assess...
Source: International Journal of Imaging Systems and Technology - May 19, 2015 Category: Radiology Authors: Sang-In Park, Jin‐Hee Lee, Yong‐An Chung, Moon‐Seo Park, Hyun Sunwoo, Kwan‐Sung Lee, Yun‐Young Sunwoo Tags: Research Article Source Type: research

The Effect of Acori graminei Rhizoma and Extract Fractions on Spatial Memory and Hippocampal Neurogenesis in Amyloid Beta 1-42 Injected Mice.
This study aimed to investigate the neuroprotective effects of different extract fractions from AGR against Alzheimer disease-like symptoms induced by Amyloid Beta (Aß) 1-42 intra-hippocampal injection. On day 7 after intra-hippocampal injection of saline or Aβ1-42, spatial memory was assessed by the first Morris water maze, followed by 3-week intra-gastric administration of saline or water extract, volatile oil fraction, or defatted decoction fraction of AGR respectively. Mice were subsequently subjected to the second Morris water maze task. Levels of Aβ1-42 and expressions of doublecortin and nestin in the hippocampus...
Source: CNS and Neurological Disorders Drug Targets - February 25, 2015 Category: Drugs & Pharmacology Authors: Ma Y, Tian S, Sun L, Yao S, Liang Z, Li S, Liu J, Zang L, Li G Tags: CNS Neurol Disord Drug Targets Source Type: research

Could curry spice boost brain cell repair?
ConclusionThis laboratory and animal research has found that an extract from turmeric (aromatic turmerone) seems to increase the growth and differentiation of neural stem cells (NSCs). However, this research is in the very early stages. So far, the extract has only been added to brain stem cells in the laboratory, or directly injected into the brains of only three rats. Though NSCs have some ability to regenerate brain cells after damage, this is usually not enough to have an effect in degenerative brain diseases such as Alzheimer’s. The hope is that by boosting the number of NSCs, they could be more effective at repairi...
Source: NHS News Feed - September 26, 2014 Category: Consumer Health News Tags: Food/diet Neurology Source Type: news

Social representation and practices related to dementia in Hai District of Tanzania
Conclusions: Knowledge about dementia is low and the symptoms are accepted as a problem of old age. PWD and carers demonstrate pluralistic behaviour in seeking help from modern care, prayers and traditional healers. The disease adds significant burden to family members. Family and caregivers need more education on early recognition of symptoms and cost effective management of dementia at family level. Faith-based organizations could play an important role in dementia interventions. At a national level effective policy and improvement of the health care system to address the needs of PWD and their families are imperative.
Source: BMC Public Health - Latest articles - March 19, 2014 Category: Consumer Health News Authors: Declare MushiAmen RongaiStella-Maria PaddickCatherine DotchinChauka MtuyaRichard Walker Source Type: research

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