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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Dementia
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Total 74 results found since Jan 2013.
Alteration in brain functional connectivity in patients with post-stroke cognitive impairment during memory task: A fNIRS study
Post-stroke cognitive impairment (PSCI) refers to a spectrum of cognitive deterioration following stroke, ranging from mild cognitive impairment to dementia. Cortical plastic alterations associated with post-stroke cognitive impairment are not well documented. It is universally acknowledged as a prevalent and severe clinical syndrome that has an adverse influence on the prognosis of stroke patients [1]. Although PSCI is an umbrella term for a variety of pathological conditions, memory, and cognition impairments are the most troubling for stroke survivors and their carers [2].
Source: Journal of Stroke and Cerebrovascular Diseases - July 29, 2023 Category: Neurology Authors: Ying Kong, Wenna Peng, Jing Li, Chunjiao Zhu, Changjie Zhang, Yongmei Fan Source Type: research
Physical activity in vascular cognitive impairment: Systematic review with meta-analysis
Vascular cognitive impairment (VCI) is the second most common cause of cognitive impairment worldwide and includes a spectrum from vascular cognitive impairment no dementia (VCIND) to vascular dementia (VaD). There is no specific pharmacological treatment approved for VCI. Physical activity has been indicated to be a promising preventive measure for cognition, with direct as indirectly benefits, while improving several modifiable vascular risk factors, so potentially effective when considering VCI.
Source: Journal of Stroke and Cerebrovascular Diseases - May 6, 2023 Category: Neurology Authors: Joana V ítor, Catarina Melita, Mário Rodrigues, Diana Aguiar de Sousa, João Costa, JM Ferro, Ana Verdelho Source Type: research
Validity of stroke severity assessment using medical records in a population-based cohort
Initial stroke severity is an important prognostic factor for outcome after acute stroke, in terms of functional dependency, post-stroke dementia, and mortality.1,2 Whilst the majority of stroke patients who are admitted to the hospital with stroke have substantial neurological deficits, over half of all strokes that occur in the population qualify as minor stroke,3 and are managed often in outpatient care.4 Given the important differences between minor and major stroke in prognosis and management, it is important to distinguish patients on the basis of stroke severity, but assessment outside of specialised stroke centres ...
Source: Journal of Stroke and Cerebrovascular Diseases - February 18, 2023 Category: Neurology Authors: Jacqueline J. Claus, Brian B.P. Berghout, M. Kamran Ikram, Frank J. Wolters Source Type: research
Associations of carotid artery flow parameters with MRI markers of cerebral small vessel disease and patterns of brain atrophy
Cerebral small vessel disease (CSVD) affects small arteries, arterioles, veins and capillaries of the brain. Although a common and often silent condition occurring among healthy elderly people, it is associated with stroke, dementia, gait disturbances, cognitive decline and depression.1 –4 Magnetic resonance imaging (MRI) markers of CSVD include: white matter changes (WMC), microbleeds (MB) and lacunar infarctions (LAC).5 They can be investigated either individually or be viewed as a dynamic whole-brain disease.
Source: Journal of Stroke and Cerebrovascular Diseases - January 18, 2023 Category: Neurology Authors: Katarina Ellstr öm, Kasim Abul-Kasim, Arkadiusz Siennicki-Lantz, Sölve Elmståhl Source Type: research
Looking for opportunities to co-enroll: The DISCOVERY study experience
Conducting high-quality stroke trials is complex and costly. Often these trials compete for the attention of researchers and the availability of patients. Enrolling patients in more than one study concurrently has the potential to accelerate recruitment into individual studies. DISCOVERY is a multicenter, inception cohort study of cognitive impairment and dementia following ischemic or hemorrhagic stroke. At the request of site investigators, a DISCOVERY committee reviews individual studies for approval of possible concurrent co-enrollment into DISCOVERY.
Source: Journal of Stroke and Cerebrovascular Diseases - November 1, 2022 Category: Neurology Authors: Bhrugun Anisetti, Natalia Rost, Kevin Barrett, Rebecca Gottesman, Jonathan Graff-Radford, Steven Kittner, Bernadette Boden-Albala, Heather Cissel, Brittany Mills, Kaley Carman, Prashanthi Vemuri, Lisa Wruck, Manjushri Bhapkar, Katy Donahue, Soumya Gupta, Source Type: research
Association between aphasia and risk of dementia after stroke
Stroke is an established risk factor for dementia and is associated with an acute and accelerated decline in cognition. With the aging population and improvements in stroke survival, the number of patients with post-stroke dementia is expected to increase,1 which entails substantial healthcare and economic burdens for patients and caregivers.
Source: Journal of Stroke and Cerebrovascular Diseases - October 22, 2022 Category: Neurology Authors: Hui-Lin Lin, Chung-Fen Tsai, Shih-Ping Liu, Chih-Hsin Muo, Pei-Chun Chen Source Type: research
Could salt intake directly affect the cerebral microvasculature in hypertension?
Cerebral small vessel disease (CSVD) is a significant cause of stroke and dementia,1,2 as well as gait impairment and falls in the elderly.3 However, its pathophysiology is still poorly understood, and no specific treatment strategies exist.
Source: Journal of Stroke and Cerebrovascular Diseases - July 21, 2022 Category: Neurology Authors: Ana Monteiro, Pedro Castro, Gilberto Pereira, Carmen Ferreira, Cristina Duque, Farzaneh Sorond, Andrew Milstead, James P. Higgins, Jorge Pol ónia, Elsa Azevedo Source Type: research
Associations between primary care electrocardiography and non-Alzheimer dementia
To determine whether electrocardiogram (ECG) markers are associated with incident non-Alzheimer's dementia (non-AD) and whether these markers also improve risk prediction for non-AD.
Source: Journal of Stroke and Cerebrovascular Diseases - July 10, 2022 Category: Neurology Authors: Jonas L. Isaksen, Jonas Ghouse, Morten W. Skov, Morten S. Olesen, Anders G. Holst, Adrian Pietersen, Jonas B. Nielsen, Anja Maier, Claus Graff, Ruth Frikke-Schmidt, J ørgen K. Kanters Source Type: research
Quantitative Analysis of White Matter Hyperintensity: Comparison of Magnetic Resonance Imaging Image Analysis Software
White matter hyperintensity (WMH), defined as abnormal signals on magnetic resonance imaging (MRI), is an important clinical indicator of aging and dementia. Although MRI image analysis software can automatically detect WMH, the quantitative accuracy of periventricular hyperintensity (PVH) and deep white matter hyperintensity (DWMH) is unknown.
Source: Journal of Stroke and Cerebrovascular Diseases - June 9, 2022 Category: Neurology Authors: Ken-ichi Tabei, Naoki Saji, Noriko Ogama, Makiko Abe, Saeko Omura, Takashi Sakurai, Hidekazu Tomimoto Tags: Short Communication Source Type: research
Informing Patients with Acute Stroke About their Risk of Dementia: A Survey of UK Healthcare Professionals
People who have a stroke are at an increased risk of developing dementia.1,2 According to the 2021 James Lind Alliance –Stroke Association Priority Setting Partnership, cognitive issues after stroke are a key concern of people who have a stroke.3 Identifying which patients with acute stroke are at risk of dementia could help patients and their carers to plan for the future. However, informing a patient who has jus t had a stroke about their risk of dementia may cause anxiety.
Source: Journal of Stroke and Cerebrovascular Diseases - January 12, 2022 Category: Neurology Authors: Emily L. Ball, Gillian E. Mead, Eugene Y.H. Tang, Dorota Religa, Terence J. Quinn, Susan D. Shenkin Source Type: research
Association Between Oral Anticoagulants and Stroke Severity at Onset in Elderly Patients with Cardioembolic Stroke Due to Non-Valvular Atrial Fibrillation
The prevention of cardioembolic stroke is an important public health priority in Japan due to its high prevalence in elderly individuals. Compared to their younger counterparts, elderly patients with cardioembolic stroke are more likely to have multiple comorbidities, a higher risk of serious complications, such as pneumonia and heart failure, and cognitive impairments (e.g., dementia or delirium), which may adversely affect their ability to participate in active rehabilitation. These factors negatively affect clinical outcomes, and many elderly stroke survivors require long-term care despite the early implementation of intensive therapy.
Source: Journal of Stroke and Cerebrovascular Diseases - December 25, 2021 Category: Neurology Authors: Ichiro Deguchi, Takashi Osada, Shinichi Takahashi Source Type: research
Prevalence and Risk Factors of Silent Cerebral Microbleeds in Patients with Coronary Artery Disease
Coronary artery disease (CAD) and stroke are the two most common causes of death and disability worldwide, notably affecting aging populations.1 These cardiovascular disorders lead to impaired activity daily life and increase the risk of dementia.2,3 Brain magnetic resonance imaging (MRI) has excellent sensitivity in detecting ischemic lesions and can reveal asymptomatic, small, cerebral hemorrhages that are called cerebral microbleeds (CMBs).4 A systematic review reported that microbleeds were present on the MRIs of 5% of healthy adults, 34% of patients with ischemic stroke, and 60% of patients with nontraumatic intracerebral hemorrhage.
Source: Journal of Stroke and Cerebrovascular Diseases - November 22, 2021 Category: Neurology Authors: Ryo Yokoyama, Yumiko Kanzaki, Tomohiko Watanabe, Kenichiro Yamamura, Tsuyoshi Komori, Yoshihiro Takeda, Osamu Nakajima, Koichi Sohmiya, Masaaki Hoshiga Source Type: research
Sex Differences in the Relationship Between Arterial Stiffness and Cognitive Function in Older Adults
Currently, dementia is a public health priority. The World Health Organization estimates 50 million people worldwide have dementia and every year there are nearly 10 million new cases.1 Dementia is a major cause of disability and dependency among older adults.1 As such, a better understanding of the mechanisms underlying cognitive decline will aid in developing targeted therapies for treatment and prevention.
Source: Journal of Stroke and Cerebrovascular Diseases - October 26, 2021 Category: Neurology Authors: Elizabeth Dao, Cindy K. Barha, Mij Santos, Madison Welch, Teresa Liu-Ambrose Source Type: research
One Disease with two Faces: Semidominant Inheritance of a Novel HTRA1 Mutation in a Consanguineous Family
Cerebral small vessel disease (CSVD) is a common form of neurological disease in elderly that leads to stroke, dementia, mood disturbance and gait problems. In the recent years, several inherited forms of CSVD have been recognized and linked to genes on autosomes and X chromosome.1 Among these, Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CARASIL, MIM 600142) and Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL, MIM 125310, MIM 616779) are two single-gene disorders characterized with progressive ischemic leukoencephalopathy, ...
Source: Journal of Stroke and Cerebrovascular Diseases - July 21, 2021 Category: Neurology Authors: Can Ebru Bekircan-Kurt, Arda Çetinkaya, Rahsan Gocmen, Can Koşukcu, Figen Soylemezoglu, Ethem Murat Arsava, Asli Tuncer, Sevim Erdem-Ozdamar, Nurten A. Akarsu, Mehmet Akif Topcuoglu Source Type: research
Volume of White Matter Hyperintensities, and Cerebral Micro-Bleeds
White matter hyperintensities (WMH) indicate the presence of patchy hyper-intense areas visible on FLAIR-MRI.1,2 WMH are visible in several neurological conditions, (cerebral small vessel disease, dementia, mood and cognitive disorders)3 –5 and these are associated with other pathologies such as stroke and hypertension.6 Moreover, their prevalence increases in elderly subjects.7 However, Pantoni et al.8 speculated that the clinical significance of WMH is not completely defined, and only most severe degrees of WMH seem to have an effect on cognitive functions.
Source: Journal of Stroke and Cerebrovascular Diseases - June 6, 2021 Category: Neurology Authors: Antonella Balestrieri, Pierleone Lucatelli, Harman S. Suri, Roberto Montisci, Jasjit S. Suri, Max Wintermark, Alessandra Serra, Xiaoguang Cheng, Cheng Jinliang, Roberto Sanfilippo, Luca Saba Source Type: research
