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Source: Lupus
Condition: Hughes Syndrome
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Total 29 results found since Jan 2013.
Lupus, antiphospholipid syndrome, and stroke: An attempt to crossmatch
Lupus. 2023 Mar 20:9612033231165151. doi: 10.1177/09612033231165151. Online ahead of print.ABSTRACTCerebrovascular accidents (CVAs) or strokes are part of the common thrombotic manifestations of Systemic Lupus Erythematosus (SLEs) and Antiphospholipid syndrome (APS). Such neurological thrombotic events tend to occur in patients with SLE at a higher frequency when Antiphospholipid antibodies (aPLs) are present, and tend to involve the large cerebral vessels. The mechanism of stroke in SLE can be driven by complement deposition and neuroinflammation involving the blood-brain barrier although the traditional cardiovascular ri...
Source: Lupus - March 20, 2023 Category: Rheumatology Authors: Georges El Hasbani Imad Uthman Source Type: research
What you need to know about migraine in Hughes syndrome patients
CONCLUSION: Most neurologists don't see or recognize many aPL-positive patients in their practice, so hematologists and rheumatologists who see these patients should recognize that refractory headache may be a manifestation of their immune-mediated hypercoagulable disorder and understand that the potential risks of not addressing this issue may be high.PMID:36708185 | DOI:10.1177/09612033231153790
Source: Lupus - January 28, 2023 Category: Rheumatology Authors: J R Schofield K L Hassell Source Type: research
Direct oral anticoagulants versus warfarin in patients with antiphospholipid syndrome: A meta-analysis of randomized controlled trials
CONCLUSION: DOACs were associated with higher rates of arterial thrombosis than warfarin in patients with APS, especially in the triple-positive group. However, a higher risk of recurrent venous thrombosis was not found in APS patients treated with DOACs compared to those treated with warfarin.PMID:35968627 | DOI:10.1177/09612033221118463
Source: Lupus - August 15, 2022 Category: Rheumatology Authors: Young H Lee Gwan G Song Source Type: research
Disability and cognitive impairment are interdependent in primary antiphospholipid syndrome
CONCLUSIONS: Disability in PAPS and CI are interdependent. New treatment options and neurocognitive stimulation strategies are necessary to maintain functionality and prevent further cognitive dysfunction in PAPS patients.PMID:35657275 | DOI:10.1177/09612033221106647
Source: Lupus - June 3, 2022 Category: Rheumatology Authors: Gabriela Medina Erik Cim é-Aké Raquel Bonilla-V ázquez Olga Vera-Lastra Miguel Ángel Saavedra Mar ía Pilar Cruz-Domínguez Luis J Jara Source Type: research
Antiphospholipid syndrome-mediated acute cerebrovascular diseases and long-term outcomes
CONCLUSION: We found no differences between stroke subtypes and APS types. aPL profiles were not associated with any of the acute cerebrovascular diseases described in this cohort. CVT may be an initial thrombotic manifestation of APS with low mortality and good long-term functional outcome.PMID:35042376 | DOI:10.1177/09612033221074178
Source: Lupus - January 19, 2022 Category: Rheumatology Authors: Miguel Garc ía-Grimshaw Diego Rub én Posadas-Pinto Amado Jim énez-Ruiz Sergio Iv án Valdés-Ferrer Arturo Cadena-Fern ández Jos é Jiram Torres-Ruiz Jos é Domingo Barrientos-Guerra Margarita Amancha-Gabela Erwin Chiquete Fernando Daniel Flores-Silva Source Type: research
Antiphospholipid antibodies and cerebrovascular thrombosis in the pediatric population: Few answers to many questions
Lupus. 2021 Jun 4:9612033211021488. doi: 10.1177/09612033211021488. Online ahead of print.ABSTRACTMost of the knowledge in pediatric antiphospholipid syndrome (APS) is derived from studies performed on the adult population. As in adults, antiphospholipid antibodies (aPL) can contribute to thrombosis, especially cerebrovascular thrombosis, in neonates and children. Since aPL have the potential to cross the placental barrier, and since the pediatric population is prone to infections, re-testing for their positivity is essential to specify their role in cerebrovascular thrombosis.In this review, we aimed at assessing the prev...
Source: Lupus - June 4, 2021 Category: Rheumatology Authors: Georges El Hasbani Ali T Taher Nadine Sunji Savino Sciascia Imad Uthman Source Type: research
