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The long-term outcomes of depression up to 10 years after stroke; the South London Stroke Register
Conclusions Depression is independently associated with poor health outcomes.
Source: Journal of Neurology, Neurosurgery and Psychiatry - April 10, 2014 Category: Neurosurgery Authors: Ayerbe, L., Ayis, S., Crichton, S., Wolfe, C. D. A., Rudd, A. G. Tags: Long term care, Stroke, Memory disorders (psychiatry) Cerebrovascular disease Source Type: research

Patient outcomes up to 15 years after stroke: survival, disability, quality of life, cognition and mental health
Conclusions One in five people live at least 15 years after a stroke and poor functional, cognitive and psychological outcomes affect a substantial proportion of these long-term survivors. As the global population of individuals with cardiovascular long-term conditions grows, research and health services will need to increasingly focus on preventing and managing the long-term consequences of stroke.
Source: Journal of Neurology, Neurosurgery and Psychiatry - September 12, 2016 Category: Neurosurgery Authors: Crichton, S. L., Bray, B. D., McKevitt, C., Rudd, A. G., Wolfe, C. D. A. Tags: JNNP Patients' choice, Long term care, Stroke, Memory disorders (psychiatry) Cerebrovascular disease Source Type: research

Impact of anxiety on verbal and visuospatial working memory in patients with acute stroke without severe cognitive impairment
Conclusions In a stressful context, the contribution of state anxiety to reduced working memory performance is more pronounced in patients with acute stroke than in controls. These results are of particular relevance for clinicians assessing patients in the acute phase of stroke in which anxiety is highly prevalent.
Source: Journal of Neurology, Neurosurgery and Psychiatry - April 13, 2015 Category: Neurosurgery Authors: Grosdemange, A., Monfort, V., Richard, S., Toniolo, A.-M., Ducrocq, X., Bolmont, B. Tags: Stroke, Memory disorders (psychiatry) Cerebrovascular disease Source Type: research

Anxiety and working memory after stroke: implications for norm-referenced methods of identifying cognitive deficits
It is well established that stroke can result in impairments of cognitive functioning, particularly early after stroke onset.1 These cognitive impairments have a negative impact on activities of daily living,2 and are associated with lower mood and poorer quality of life.3 Improvement of cognitive functioning is therefore an important goal of rehabilitation. In clinical settings, the presence of cognitive impairment is usually determined by means of standardised psychometric assessment. A patient's cognitive test performance is compared to the performance of a non-stroke control group on the same test(s). The most appropri...
Source: Journal of Neurology, Neurosurgery and Psychiatry - April 13, 2015 Category: Neurosurgery Authors: Gillespie, D. C. Tags: Stroke, Memory disorders (psychiatry) Editorial commentaries Source Type: research

050 Feasibility of an automated assessment to measure cognition and mood in the acute stroke setting
Discussion Screening was adapted due to Covid pandemic and utilising remote consent and participa- tion allowed the project to continue.
Source: Journal of Neurology, Neurosurgery and Psychiatry - August 12, 2022 Category: Neurosurgery Authors: Bell, S., Harkness, K., Roman, M., Gardner, J., Richards, E., Howe, J., Sikaonga, M., Mirheidari, B., Christensen, H., Blackburn, D. Tags: Poster presentations Source Type: research

TEARS: a longitudinal investigation of the prevalence, psychological associations and trajectory of poststroke emotionalism
This study aimed to assess the prevalence and course of PSE over the first year poststroke, and its psychological associations. Methods Consenting stroke survivors who were physically and cognitively able to participate were assessed within 2 weeks, 6 and 12 months of stroke to determine PSE point prevalence using a diagnostic, semistructured PSE interview (Testing Emotionalism After Recent Stroke-Diagnostic Interview). At the same assessments, neuropsychological and disability status were determined using Hospital Anxiety and Depression Scale, Abbreviated Mental Test, National Institute of Health Stroke Scale, Barthel In...
Source: Journal of Neurology, Neurosurgery and Psychiatry - July 14, 2022 Category: Neurosurgery Authors: Broomfield, N. M., West, R., Barber, M., Quinn, T. J., Gillespie, D., Walters, M., House, A. Tags: Editor's choice Neuropsychiatry Source Type: research

Autoimmune gabab antibody encephalitis associated with non-malignant lung lesion
GABAb receptor autoimmune encephalitis is a potentially treatable disorder characterised by seizures, memory deficits, increased anxiety and mood dysregulation. In some patients it is associated with small–cell lung cancer and with other autoantibodies. We are presenting a case of GABAb receptor autoimmune encephalitis which was associated with non–malignant lung lesion, likely inflammatory in nature. A 62 year old woman presented with recent onset depression and tonic–clonic seizures. CT head showed patchy white matter changes particularly in the left frontal lobe. Initial treatment for suspected infecti...
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Wysota, B., Teare, L., Karim, A., Jacob, S. Tags: Immunology (including allergy), Epilepsy and seizures, Infection (neurology), Stroke, Drugs: psychiatry, Memory disorders (psychiatry), Radiology, Drugs: musculoskeletal and joint diseases, Radiology (diagnostics) Association of British Neurologists (AB Source Type: research

Anti glutamic acid decarboxylase antibody mediated encephalopathy while on etanercept in a patient with multiple autoimmune diseases
A 39 year old lady presented with an altered mental state and unsteadiness of gait. She had a history of juvenile idiopathic arthritis, autoimmune thyroiditis and alopecia, protein S deficiency with vena cava thrombosis, previous excision of ovarian mass and vasculitic rash. There was a previous history of ovarian mass and her immunomodulatory therapy for arthritis over the previous year was Etanercept. She used recreational cannabis but denied any other illicit drug usage. Her affect was variable and at times inappropriate with frequent laughter. She would spit regularly. There was anxiety and a prevailing sensation of do...
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: MacDougall, N., Waddell, B., O'Riordan, J. I. Tags: Immunology (including allergy), Brain stem / cerebellum, Drugs: CNS (not psychiatric), Epilepsy and seizures, Infection (neurology), Stroke, Drugs misuse (including addiction), Connective tissue disease, Musculoskeletal syndromes Association of British Source Type: research

'the mind is its own place': amelioration of claustrophobia in a patient with semantic dementia
Specific phobia is defined as marked, persistent and excessive or unreasonable fear when in the presence of, or when anticipating an encounter with, a specific object or situation.1 Here we describe amelioration of one common and disabling example, claustrophobia, following the onset of semantic dementia. Our patient had a clinical diagnosis of claustrophobia dating from her 20s and severe enough to cause her difficulties in daily life. She had habitually avoided lifts, windowless rooms, train travel and flying on account of her intense fear of being enclosed. At the age of 61, she developed a typical syndrome of semantic ...
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Clarke, C., Fletcher, P., Cifelli, A., Warren, J. Tags: Dementia, Neuroimaging, Stroke, Anxiety disorders (including OCD and PTSD), Memory disorders (psychiatry), Radiology, Radiology (diagnostics) Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), London, 23- Source Type: research

Spontaneous intracranial hypotension: clinical features in eight cases
Conclusions SIH is an under–recognised but fairly common disorder. Clinical examination is usually normal, and confirmation of the diagnosis requires investigations and treatment not used routinely in the management of headache. Investigations, including contrast–enhanced neuroimaging, are often normal in the acute or chronic phase. Clinical history taking skills are therefore paramount in recognising this disorder. Characteristic features include a new daily persistent headache in a cranio–cervical distribution, with often bizarre sounding additional symptoms. Our results challenge the prevailing notions...
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Anderson, J., Corkill, R. Tags: Headache (including migraine), Pain (neurology), Stroke, Ear, nose and throat/otolaryngology Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), London, 23-24 October 2013 Source Type: research

A rare cause of headache-the importance of a tissue diagnosis and perseverance
A 64 year old diabetic hypertensive milkman presented in September 2011 with 4 months progressive constant right frontotemporal retro–orbital pain. It was worse at night affecting sleep with slight right field blurring and later vomiting. Full examination including blood pressure was normal with acuities 6/9. Tension type headache was considered. Initial brain CT was reported as normal. With concern about giant cell arteritis steroids were trialled although ESR was 8 and CRP 25 with no other clinical features: pain reduction was short–lived and temporal artery biopsy negative. Symptoms worsened despite analgesi...
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Defty, H., Cavazza, A., Warner, G. Tags: Immunology (including allergy), Cranial nerves, Headache (including migraine), Neurooncology, Pain (neurology), Stroke, Hypertension, CNS cancer, Ophthalmology, Pain (palliative care), Anxiety disorders (including OCD and PTSD), Radiology, Disability, Dru Source Type: research

Processing of emotional information in the human subthalamic nucleus
Conclusions These results demonstrate that the ventral part of the STN processes the emotional valence of stimuli independently of the motor context and that dopamine enhances processing of pleasant information. These findings confirm the specific involvement of the STN in emotional processes in human, which may underlie the behavioural changes observed in patients with deep brain stimulation.
Source: Journal of Neurology, Neurosurgery and Psychiatry - November 13, 2013 Category: Neurosurgery Authors: Buot, A., Welter, M.-L., Karachi, C., Pochon, J.-B., Bardinet, E., Yelnik, J., Mallet, L. Tags: Drugs: CNS (not psychiatric), Parkinson's disease, Stroke, Anxiety disorders (including OCD and PTSD), Mood disorders (including depression) Cognitive neurology Source Type: research

Is there anything distinctive about epileptic deja vu?
Conclusions Déjà vu is common and qualitatively similar whether it occurs as an epileptic aura or normal phenomenon. However ictal déjà vu occurs more frequently and is accompanied by several distinctive features. It is distinguished primarily by ‘the company it keeps’.
Source: Journal of Neurology, Neurosurgery and Psychiatry - January 17, 2014 Category: Neurosurgery Authors: Warren-Gash, C., Zeman, A. Tags: Epilepsy and seizures, Headache (including migraine), Pain (neurology), Stroke Neuropsychiatry Source Type: research

Mild traumatic brain injury and epilepsy: alcohol misuse may underpin the association
Mild traumatic brain injury (mTBI) is associated with various neurological and cognitive problems, but causality is often less clear. For example, postconcussion syndrome (PCS) was widely assumed to be a consequence of neural damage until it was demonstrated that: (1) the symptoms of PCS are not specific to brain injury, being common in the general population,1 (2) ‘PCS’ is as common in those who experience physical trauma without brain injury as those who experience mTBI,2 (3) preinjury factors, such as a history of anxiety or affective disorder, predict development of PCS,2 (4) PCS has a strong relationship w...
Source: Journal of Neurology, Neurosurgery and Psychiatry - May 6, 2014 Category: Neurosurgery Authors: Welch, K. A., Derry, C. Tags: Epilepsy and seizures, Neurological injury, Stroke, Trauma CNS / PNS, Unwanted effects / adverse reactions, Alcohol-related disorders, Drugs misuse (including addiction), Mood disorders (including depression), Trauma, Injury Editorial commentaries Source Type: research

Interoceptive sensitivity and sense of body ownership in patients with functional neurological symptoms
Conclusion Patients with FMS have poor interoceptive sensitivity. This could relate to impairments of assessment of emotional state in these patients.
Source: Journal of Neurology, Neurosurgery and Psychiatry - July 9, 2014 Category: Neurosurgery Authors: Ricciardi, L., Demartini, B., Crucianelli, L., Edwards, M. J., Fotopoulou, A. Tags: Stroke POSTER ABSTRACTS Source Type: research

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