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Carotid artery structure and hemodynamics and their association with adverse vascular events in left ventricular assist device patients
We examined the association of these measures with the composite outcome as well as individual subcomponents such as stroke. After adjusting for established risk factors, the composite adverse outcome was associated with pre-operative moderate-to-severe carotid plaque (OR 5.08, 95% CI 1.67 –15.52) as well as pre-operative internal carotid artery stenosis (OR 9.02, 95% CI 1.06–76.56). In contrast, altered hemodynamics during LVAD support were not associated with the composite outcome. Our findings suggest that pre-existing atherosclerosis possibly in combination with LVAD hemodynam ics may be an important contributor to...
Source: Journal of Artificial Organs - January 18, 2021 Category: Transplant Surgery Source Type: research