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Specialty: Endocrinology
Source: Molecular and Cellular Endocrinology
Condition: Bleeding
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Total 1 results found since Jan 2013.
Pathophysiological consequences of receptor mistraffic: Tales from the platelet P2Y12 receptor
Publication date: Available online 14 February 2017 Source:Molecular and Cellular Endocrinology Author(s): Margaret R. Cunningham, Riyaad Aungraheeta, Stuart J. Mundell Genetic variations in G protein-coupled receptor (GPCR) genes can disrupt receptor function in a wide variety of human genetic diseases, including platelet bleeding disorders. Platelets are critical for haemostasis with inappropriate platelet activation leading to the development of arterial thrombosis, which can result in heart attack and stroke whilst decreased platelet activity is associated with an increased risk of bleeding. GPCRs expressed on the sur...
Source: Molecular and Cellular Endocrinology - February 14, 2017 Category: Endocrinology Source Type: research
