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Source: The Annals of Pharmacotherapy
Condition: Bleeding
Education: Study

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Total 33 results found since Jan 2013.

Major Bleeding Postadministration of Tenecteplase Versus Alteplase in Acute Ischemic Stroke
CONCLUSIONS AND RELEVANCE: Tenecteplase had similar rates of major bleeding versus alteplase and may be a reasonable alternative in the treatment of acute ischemic stroke.PMID:36004394 | DOI:10.1177/10600280221120211
Source: The Annals of Pharmacotherapy - August 25, 2022 Category: Drugs & Pharmacology Authors: Mary N Walton Leslie A Hamilton Sonia Salyer Brian F Wiseman Ann M Forster A Shaun Rowe Source Type: research

Perioperative Antiplatelet Bridging With Cangrelor: A Cohort Study and Narrative Review
CONCLUSION AND RELEVANCE: This study suggests that cangrelor bridging may be a reasonable alternative to holding oral P2Y12 inhibitors in patients requiring interruption of antiplatelet therapy for an urgent surgery/invasive procedure.PMID:36004393 | DOI:10.1177/10600280221120310
Source: The Annals of Pharmacotherapy - August 25, 2022 Category: Drugs & Pharmacology Authors: Alok Salgia Chelsea K Krueger Michael A Gillette Source Type: research

Effectiveness and Safety of Enoxaparin Versus Unfractionated Heparin as Thromboprophylaxis in Hospitalized COVID-19 Patients: Real-World Evidence
CONCLUSION AND RELEVANCE: When compared with UFH, enoxaparin was associated with a significant reduction in thrombotic events or mortality among COVID-19 patients. The results need confirmation from randomized controlled trials.PMID:35942505 | DOI:10.1177/10600280221115299
Source: The Annals of Pharmacotherapy - August 9, 2022 Category: Drugs & Pharmacology Authors: Lina H AlLehaibi Mukhtar Alomar Abdulaziz Almulhim Sarah Al-Makki Nazar R Alrwaili Shahad Al-Bassam Semat Alsultan Jenan Al Saeed Mohammad Alsheef Ivo Abraham Ahmad Alamer Source Type: research

A Review of Direct Oral Anticoagulants in Patients With Stage 5 or End-Stage Kidney Disease
CONCLUSIONS: If OACs for stroke prevention with AF are deemed necessary, apixaban or rivaroxaban can be considered. DOACs cannot currently be recommended over warfarin in patients with CKD-5 or ESKD and VTE.PMID:34459281 | DOI:10.1177/10600280211040093
Source: The Annals of Pharmacotherapy - August 30, 2021 Category: Drugs & Pharmacology Authors: Jessica A Starr Nathan A Pinner Melanie Mannis Mary Katherine Stuart Source Type: research

The Impact of Body Weight and Renal Function on the Risk of Bleeding With Direct Oral Anticoagulants in Atrial Fibrillation
CONCLUSION AND RELEVANCE: This study demonstrates an association between higher baseline SCr, elevated HASBLED score, and lower weight, with an increased risk of bleeding in patients with NVAF or AFL receiving a DOAC. These findings add to prescribing considerations when initiating DOACs. Closer monitoring is advised for patients with significant renal dysfunction and/or low body weight, even with renal dose adjustments.PMID:33601914 | DOI:10.1177/1060028021995201
Source: The Annals of Pharmacotherapy - February 19, 2021 Category: Drugs & Pharmacology Authors: Hannah Whittemore Andrew K Posen Erika L Hellenbart Vicki Groo Eric Wenzler Jessica J Tilton Source Type: research

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