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Relationship Between Direct Oral Anticoagulant Doses and Clinical Outcomes in Elderly Patients With Non-Valvular Atrial Fibrillation 　- ANAFIE Registry Sub-Analysis
CONCLUSIONS: Inappropriate low DOAC doses (under- or off-label dose) were not associated with stroke/SEE or major bleeding but were associated with all-cause death.PMID:37482411 | DOI:10.1253/circj.CJ-23-0143
Source: Circulation Journal - July 23, 2023 Category: Cardiology Authors: Masaharu Akao Hiroshi Inoue Takeshi Yamashita Hirotsugu Atarashi Takanori Ikeda Yukihiro Koretsune Ken Okumura Shinya Suzuki Hiroyuki Tsutsui Kazunori Toyoda Atsushi Hirayama Masahiro Yasaka Takenori Yamaguchi Satoshi Teramukai Tetsuya Kimura Yoshiyuki Mo Source Type: research

Dual Antiplatelet Therapy Duration After Multivessel Optimal Intravascular Ultrasound-Guided Percutaneous Coronary Intervention
CONCLUSIONS: The adoption of short DAPT duration was still low in this trial conducted after the release of the STOPDAPT-2 trial results. The 1-year incidence of cardiovascular events was not different between the shorter and longer DAPT groups, suggesting no apparent benefit of prolonged DAPT in reducing cardiovascular events even in patients who undergo multivessel PCI.PMID:37197941 | DOI:10.1253/circj.CJ-23-0141
Source: Circulation Journal - May 17, 2023 Category: Cardiology Authors: Ko Yamamoto Hiroki Shiomi Takeshi Morimoto Akiyoshi Miyazawa Hiroki Watanabe Sunao Nakamura Satoru Suwa Takenori Domei Koh Ono Hiroki Sakamoto Masataka Shigetoshi Ryoji Taniguchi Hideki Okayama Takafumi Yokomatsu Masahiro Muto Ren Kawaguchi Koichi Kishi M Source Type: research

Clopidogrel Use in CYP2C19 Loss-of-Function Carriers With High Bleeding Risk After Percutaneous Coronary Intervention
CONCLUSIONS: Among patients with HBR, clopidogrel use in CYP2C19 LOF carriers was significantly associated with increased ischemic events after PCI.PMID:36792180 | DOI:10.1253/circj.CJ-22-0826
Source: Circulation Journal - February 15, 2023 Category: Cardiology Authors: Yuichi Sawayama Yukinori Tomita Soji Kohyama Yosuke Higo Kenji Kodama Kohei Asada Noriaki Yagi Megumi Fukuyama Atsushi Hayashi Wataru Shioyama Hiroshi Sakai Tomoya Ozawa Tetsuichiro Isono Daiki Hira Takashi Yamamoto Shin-Ya Morita Yoshihisa Nakagawa Source Type: research

Thrombocytopenia Following Perceval Sutureless Aortic Valve Replacement in Asian Patients
CONCLUSIONS: Thrombocytopenia was common after Perceval sutureless AVR, although its impact was not significant. Although Perceval sutureless AVR was found to be a safe and effective option, preoperative assessment of potential bleeding should be performed and the Perceval valve should not be used for patients with a high bleeding risk.PMID:36709983 | DOI:10.1253/circj.CJ-22-0587
Source: Circulation Journal - January 29, 2023 Category: Cardiology Authors: Taisuke Nakayama Yoshitsugu Nakamura Fumiaki Shikata Masaki Ushijima Yuto Yasumoto Daiki Yoshiyama Miho Kuroda Shintaro Sawa Ryo Tsuruta Akira Furutachi Takuya Narita Yujiro Ito Source Type: research

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