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Patent Foramen Ovale Closure Versus Medical Therapy for Cryptogenic Stroke: An Updated Systematic Review and Meta-Analysis
ConclusionPFO closure is associated with a significant reduction in the risk of stroke compared to medical management. However, it causes an increased risk of atrial fibrillation.
Source: Indian Heart Journal - October 22, 2019 Category: Cardiology Source Type: research

Thrombolysis with Reteplase in Acute Pulmonary Embolism
ConclusionsDouble bolus reteplase given with heparin is effective in the treatment of high, intermediate risk pulmonary embolism with minimal risk of bleeding.
Source: Indian Heart Journal - September 22, 2019 Category: Cardiology Source Type: research

Therapeutic Experience of Ticagrelor in Indian Patients with Acute Coronary Syndrome: a Non-Interventional, Prospective, Observational Study
ConclusionTicagrelor has been used across ACS types and in different management strategies in real world settings in India. The incidence of clinical events was lower as compared to data in literature. ClinicalTrials.gov Identifier: NCT02408224
Source: Indian Heart Journal - August 30, 2019 Category: Cardiology Source Type: research

Short- and Long-Term Follow-up of Antithrombotic Management Patterns in Patients Hospitalized with Acute Coronary Syndrome (ACS): Indian Subgroup of EPICOR-Asia Study
ConclusionThis study showed a gap between international recommendations and implementation for managing ACS in Indian patients.. Most of the patients prefer to undergo invasive management instead of noninvasive therapy.. At the end of 2-year follow up more than half of the population were receiving DAPT, with most patients on receiving a combination of aspirin and clopidogrel The mortality along with composite events of death, MI, or ischemic stroke was highest for NSTEMI patients.
Source: Indian Heart Journal - January 3, 2019 Category: Cardiology Source Type: research

Risk profiles and One-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry
ConclusionCompared to previously published registries from India, GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data shows that compared to the rest of the world, Indian AF patients are younger with more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are under-dosed compared with the global average in GARFIELD-AF.
Source: Indian Heart Journal - September 12, 2018 Category: Cardiology Source Type: research

Gender disparities with the use of percutaneous left ventricular assist device in patients undergoing percutaneous coronary intervention complicated by cardiogenic shock: From pVAD Working Group
ConclusionsDespite the small number of cohorts, this study did not reveal any significant differences among gender with the use of percutaneous left ventricular assist devices for PCI in patients with acute myocardial infarction complicated by CS. However, initiation of Impella prior to PCI may be associated with improved mortality and morbidity in both genders.
Source: Indian Heart Journal - July 10, 2018 Category: Cardiology Source Type: research

Gender Disparities with the Use of Percutaneous Left Ventricular Assist Device in Patients Undergoing Percutaneous Coronary Intervention Complicated by Cardiogenic Shock: From pLVAD Working Group
Conclusions Despite the small number of cohorts, this study did not reveal any significant differences among gender with the use of percutaneous left ventricular assist devices for PCI in patients with acute myocardial infarction complicated by CS. However, initiation of Impella prior to PCI may be associated with improved mortality and morbidity in both genders.
Source: Indian Heart Journal - April 30, 2018 Category: Cardiology Source Type: research