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Two older drugs could be 'repurposed' to fight dementia
Conclusion This early stage experimental research has demonstrated a beneficial neurological effect of trazodone and dibenzoylmethane on mice with diseases mimicking neurodegenerative diseases. It is important to acknowledge that this is animal research and therefore the drugs might not have the same effect when they are trialled on humans. That being said, trazodone is already an approved drug for depression and sleep problems and has therefore already passed safety tests. If the mechanisms of neurodegeneration in humans and mice are similar, it is possible trazodone could be used in the future in treating Alzheimer's and...
Source: NHS News Feed - April 20, 2017 Category: Consumer Health News Tags: Older people Neurology Medication Source Type: news

Excess body fat now linked to 13 different types of cancer
"Experts have linked eight more cancers to being overweight or obese, nearly tripling the list from five to 13," the Daily Mail reports. This is the latest finding of the International Agency for Research on Cancer (IARC), a group of cancer experts from around the world that look at risk factors for cancer.  What is the basis for these reports? The headlines are based on a report published in the peer-reviewed New England Journal of Medicine. The report is not exactly new research, but a review of previously published studies that looked at the link between weight and cancers. It is the result of a working g...
Source: NHS News Feed - August 25, 2016 Category: Consumer Health News Tags: Cancer Obesity Lifestyle/exercise Source Type: news

UK 'among worst' for cancer linked to obesity
Conclusion This international study has shown alarming increases in cases of cancer that can be attributed to high BMI. Overall, they estimated that 3.6% of cancers in adults (aged over 30 years) worldwide are caused by high BMI, with the proportion attributed to obesity slightly higher in women than in men. In the UK, 4.4% of all cases of cancer per year in men and 8.2% of all cases of cancer per year in women, were estimated to be attributable to obesity. The research focused on cancers that the WCRF has already established are linked to high BMI. When looking at these cancers, the UK was joint second highest in the worl...
Source: NHS News Feed - November 27, 2014 Category: Consumer Health News Tags: Cancer Obesity Source Type: news

Diabetes drugs may be linked to pancreatic cancer
Conclusion This article presents important concerns that glucagon-like peptide-1 (GLP-1) agonists and dipeptidylpeptidase-4 (DPP-4) inhibitors could potentially increase the risk of inflammation and cancerous changes in the pancreas. The agencies that regulate medicines in Europe and the USA are aware of these issues, and told the BMJ that their analyses show increased reporting of pancreatic cancer among people taking these types of drugs. However, the agencies note that it has not been established whether these drugs directly cause the adverse effects seen in the pancreas. Both agencies are reviewing emerging eviden...
Source: NHS News Feed - June 10, 2013 Category: Consumer Health News Tags: Medication Diabetes QA articles Source Type: news