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Amelioration of oxidative stress in differentiated neuronal cells by rutin regulated by a concentration switch
Publication date: December 2018Source: Biomedicine & Pharmacotherapy, Volume 108Author(s): Banudevi Sivanantham, UmaMaheswari Krishnan, Vignesh RajendiranAbstractIncreasing studies have implicated superfluous production of reactive oxygen species (ROS) as a significant factor in the progress of neurodegenerative disorders ranging from ischemic stroke to amyotrophic lateral sclerosis. The possible mechanisms relating to oxidative stress and neurodegeneration are yet to be thoroughly understood. Rutin, a flavonoid, has been well documented for its beneficial and pharmacological activities against diverse targets. However, th...
Source: Biomedicine and Pharmacotherapy - September 11, 2018 Category: Drugs & Pharmacology Source Type: research