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Source: Physiological Reports
Cancer: Brain Cancers
Nutrition: Calcium
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Total 2 results found since Jan 2013.
Influence of dual ‐specificity protein phosphatase 5 on mechanical properties of rat cerebral and renal arterioles
In this study, we found that KO ofDusp5 did not alter body weights, kidney and brain weights, plasma glucose, and HbA1C levels. The expression of pERK is higher in the nucleus of primary VSMC isolated fromDusp5 KO rats.Dusp5 KO rats exhibited eutrophic vascular hypotrophy with smaller intracerebral parenchymal arterioles and renal interlobular arterioles without changing the wall ‐to‐lumen ratios. These arterioles fromDusp5 KO rats displayed higher myogenic tones, better distensibility, greater compliance, and less stiffness compared with arterioles from WT control rats. VSMC ofDusp5 KO rats exhibited a stronger contra...
Source: Physiological Reports - January 19, 2020 Category: Physiology Authors: Huawei Zhang,
Chao Zhang,
Yedan Liu,
Wenjun Gao,
Shaoxun Wang,
Xing Fang,
Ya Guo,
Man Li,
Ruen Liu,
Richard J. Roman,
Peng Sun,
Fan Fan Tags: ORIGINAL RESEARCH Source Type: research
