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Source: Brain Research Bulletin
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The phosphodiesterase-4 inhibitor, FCPR16, attenuates ischemia-reperfusion injury in rats subjected to middle cerebral artery occlusion and reperfusion.
This study indicates that FCPR16 has protective effects against cerebral ischemia-reperfusion injury through inhibiting inflammation and apoptosis via the cAMP/CREB pathway, while it has low emetogenic potential. PMID: 29155261 [PubMed - as supplied by publisher]
Source: Brain Research Bulletin - November 16, 2017 Category: Neurology Authors: Chen J, Yu H, Zhong J, Feng H, Wang H, Cheng Y, Zou Z, Huang C, Zhou Z, Zheng W, Xu J Tags: Brain Res Bull Source Type: research