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Infectious Disease: Genital Warts
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HLA-G Alleles Impact the Perinatal Father-Child HPV Transmission
This study evaluated whether human leukocyte antigen (HLA)-G alleles are important in father-to-child HPV transmission during the perinatal period. Altogether, 134 father-newborn pairs from the Finnish Family HPV Study were included. Oral, semen and urethral samples from the fathers were collected before the delivery, and oral samples were collected from their offspring at delivery and postpartum on day 3 and during 1-, 2- and 6-month follow-up visits. HLA-G alleles were tested by direct sequencing. Unconditional logistic regression was used to determine the association of the father-child HLA-G allele and genotype concord...
Source: Current Issues in Molecular Biology - July 28, 2023 Category: Molecular Biology Authors: Nelli T Suominen Michel Roger Marie-Claude Faucher Kari J Syrj änen Seija E Gr énman Stina M Syrj änen Karolina Louvanto Source Type: research
SOCS1 as a Biomarker Candidate for HPV Infection and Prognosis of Head and Neck Squamous Cell Carcinomas
This study provides new information on biological targets that may be relevant to the molecular mechanisms underpinning the occurrence and development of HNSCC. SOCS1 may play an important role in the interaction between HPV and HNSCC and serve as a potential biomarker for future therapeutic targets.PMID:37504269 | PMC:PMC10378037 | DOI:10.3390/cimb45070353
Source: Current Issues in Molecular Biology - July 28, 2023 Category: Molecular Biology Authors: Manli Guo Lijie Zhang Huihui Wang Qiaozhen Zhou Xinrang Zhu Xinyu Fu Jinlong Yang Shanhe Liu Dingcheng Guo Baoping Zhang Source Type: research
HLA-G Alleles Impact the Perinatal Father-Child HPV Transmission
This study evaluated whether human leukocyte antigen (HLA)-G alleles are important in father-to-child HPV transmission during the perinatal period. Altogether, 134 father-newborn pairs from the Finnish Family HPV Study were included. Oral, semen and urethral samples from the fathers were collected before the delivery, and oral samples were collected from their offspring at delivery and postpartum on day 3 and during 1-, 2- and 6-month follow-up visits. HLA-G alleles were tested by direct sequencing. Unconditional logistic regression was used to determine the association of the father-child HLA-G allele and genotype concord...
Source: Current Issues in Molecular Biology - July 28, 2023 Category: Molecular Biology Authors: Nelli T Suominen Michel Roger Marie-Claude Faucher Kari J Syrj änen Seija E Gr énman Stina M Syrj änen Karolina Louvanto Source Type: research
SOCS1 as a Biomarker Candidate for HPV Infection and Prognosis of Head and Neck Squamous Cell Carcinomas
This study provides new information on biological targets that may be relevant to the molecular mechanisms underpinning the occurrence and development of HNSCC. SOCS1 may play an important role in the interaction between HPV and HNSCC and serve as a potential biomarker for future therapeutic targets.PMID:37504269 | PMC:PMC10378037 | DOI:10.3390/cimb45070353
Source: Current Issues in Molecular Biology - July 28, 2023 Category: Molecular Biology Authors: Manli Guo Lijie Zhang Huihui Wang Qiaozhen Zhou Xinrang Zhu Xinyu Fu Jinlong Yang Shanhe Liu Dingcheng Guo Baoping Zhang Source Type: research
HLA-G Alleles Impact the Perinatal Father-Child HPV Transmission
This study evaluated whether human leukocyte antigen (HLA)-G alleles are important in father-to-child HPV transmission during the perinatal period. Altogether, 134 father-newborn pairs from the Finnish Family HPV Study were included. Oral, semen and urethral samples from the fathers were collected before the delivery, and oral samples were collected from their offspring at delivery and postpartum on day 3 and during 1-, 2- and 6-month follow-up visits. HLA-G alleles were tested by direct sequencing. Unconditional logistic regression was used to determine the association of the father-child HLA-G allele and genotype concord...
Source: Current Issues in Molecular Biology - July 28, 2023 Category: Molecular Biology Authors: Nelli T Suominen Michel Roger Marie-Claude Faucher Kari J Syrj änen Seija E Gr énman Stina M Syrj änen Karolina Louvanto Source Type: research
SOCS1 as a Biomarker Candidate for HPV Infection and Prognosis of Head and Neck Squamous Cell Carcinomas
This study provides new information on biological targets that may be relevant to the molecular mechanisms underpinning the occurrence and development of HNSCC. SOCS1 may play an important role in the interaction between HPV and HNSCC and serve as a potential biomarker for future therapeutic targets.PMID:37504269 | PMC:PMC10378037 | DOI:10.3390/cimb45070353
Source: Current Issues in Molecular Biology - July 28, 2023 Category: Molecular Biology Authors: Manli Guo Lijie Zhang Huihui Wang Qiaozhen Zhou Xinrang Zhu Xinyu Fu Jinlong Yang Shanhe Liu Dingcheng Guo Baoping Zhang Source Type: research
HLA-G Alleles Impact the Perinatal Father-Child HPV Transmission
This study evaluated whether human leukocyte antigen (HLA)-G alleles are important in father-to-child HPV transmission during the perinatal period. Altogether, 134 father-newborn pairs from the Finnish Family HPV Study were included. Oral, semen and urethral samples from the fathers were collected before the delivery, and oral samples were collected from their offspring at delivery and postpartum on day 3 and during 1-, 2- and 6-month follow-up visits. HLA-G alleles were tested by direct sequencing. Unconditional logistic regression was used to determine the association of the father-child HLA-G allele and genotype concord...
Source: Current Issues in Molecular Biology - July 28, 2023 Category: Molecular Biology Authors: Nelli T Suominen Michel Roger Marie-Claude Faucher Kari J Syrj änen Seija E Gr énman Stina M Syrj änen Karolina Louvanto Source Type: research
