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Drug: Taxotere

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Total 2210 results found since Jan 2013.

Kinase Inhibitor Pulldown Assay Identifies a Chemotherapy Response Signature in Triple-negative Breast Cancer Based on Purine-binding Proteins
Cancer Res Commun. 2023 Aug 15;3(8):1551-1563. doi: 10.1158/2767-9764.CRC-22-0501. eCollection 2023 Aug.ABSTRACTTriple-negative breast cancer (TNBC) constitutes 10%-15% of all breast tumors. The current standard of care is multiagent chemotherapy, which is effective in only a subset of patients. The original objective of this study was to deploy a mass spectrometry (MS)-based kinase inhibitor pulldown assay (KIPA) to identify kinases elevated in non-pCR (pathologic complete response) cases for therapeutic targeting. Frozen optimal cutting temperature compound-embedded core needle biopsies were obtained from 43 patients wit...
Source: Cell Research - August 17, 2023 Category: Cytology Authors: Junkai Wang Alexander B Saltzman Eric J Jaehnig Jonathan T Lei Anna Malovannaya Matthew V Holt Meggie N Young Mothaffar F Rimawi Foluso O Ademuyiwa Meenakshi Anurag Beom-Jun Kim Matthew J Ellis Source Type: research

Synthesis of Au-Ag bimetallic nanoparticles using Korean red ginseng (Panax ginseng Meyer) root extract for chemo-photothermal anticancer therapy
Arch Pharm Res. 2023 Aug 17. doi: 10.1007/s12272-023-01457-y. Online ahead of print.ABSTRACTGreen synthesis strategies have been widely applied for the preparation of versatile nanomaterials. Gold nanospheres with an average size of 6.95 ± 2.25 nm were green synthesized by using a 70% ethanol extract of Korean red ginseng (Panax ginseng Meyer) root as a reducing agent. A seed-mediated synthesis was conducted to prepare Au-Ag bimetallic nanoparticles using gold nanospheres as seeds. Remarkably, Au-Ag bimetallic nanoparticles with an average size of 80.4 ± 11.9 nm were synthesized. Scanning transmission electron microscopy...
Source: Archives of Pharmacal Research - August 17, 2023 Category: Drugs & Pharmacology Authors: Gayeon Lee You Jeong Lee Yeon-Jeong Kim Youmie Park Source Type: research