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Th1 Cytokines, TNF α and IFNγ, Promote Corticosteroid Resistance in Developing Human Airway Smooth Muscle.
Th1 Cytokines, TNFα and IFNγ, Promote Corticosteroid Resistance in Developing Human Airway Smooth Muscle. Am J Physiol Lung Cell Mol Physiol. 2018 Oct 18;: Authors: Britt RD, Thompson MA, Sasse SK, Pabelick CM, Gerber AN, Prakash YS Abstract Corticosteroids are commonly used to manage wheezing and asthma in pediatric populations. Although corticosteroids are effective in alleviating airway diseases, some children with more moderate-severe asthma phenotypes show corticosteroid (CS) resistance and exhibit significant airflow obstruction, persistent inflammation, and more frequent exacerbations. Previo...
Source: Am J Physiol Lung Ce... - October 18, 2018 Category: Respiratory Medicine Authors: Britt RD, Thompson MA, Sasse SK, Pabelick CM, Gerber AN, Prakash YS Tags: Am J Physiol Lung Cell Mol Physiol Source Type: research