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Specialty: Physiology
Source: Physiological Research
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Total 27 results found since Jan 2013.
NADPH oxidase 4 contributes to oxidative stress in a mouse model of myocardial infarction
Physiol Res. 2023 Apr 30;72(2):177-186.ABSTRACTOxidative stress closely related to the progression and severity of myocardial infarction (MI). Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase 4 (NOX4) is one of the major enzymes that generate reactive oxygen species (ROS) in cardiovascular system. Here, we aim to elucidate the pathological role of NOX4 in MI. MI mouse model was created by the coronary artery ligation. NOX4 was specifically knocked down in heart through intramyocardial injection of siRNA. NOX4 expression and oxidative stress indicators were determined at different time points using qRT-PCR, Weste...
Source: Physiological Research - May 9, 2023 Category: Physiology Authors: Q Huang Y Chen Source Type: research
