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Specialty: Epidemiology
Drug: Melatonin
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Total 1 results found since Jan 2013.
Involvement of ROS-alpha v beta 3 integrin-FAK/Pyk2 in the inhibitory effect of melatonin on U251 glioma cell migration and invasion under hypoxia
Conclusions:
These results suggest that melatonin exerts anti-migratory and anti-invasive effects on glioma cells in response to hypoxia via ROS-αvβ3 integrin-FAK/Pyk2 signaling pathways. This provides evidence that melatonin may be a potential therapeutic molecule targeting the hypoxic microenvironment of glioma.
Source: Epidemiologic Perspectives and Innovations - March 20, 2015 Category: Epidemiology Authors: Cheng-Shi XuZe-Fen WangXiao-Dong HuangLi-Ming DaiChang-Jun CaoZhi-Qiang Li Source Type: research
