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Specialty: Epidemiology
Condition: Schizophrenia
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TrkB interacts with ErbB4 and regulates NRG1-induced NR2B phosphorylation in cortical neurons before synaptogenesis
Conclusions:
BDNF/TrkB signaling plays an important role in the NRG1-stimulated NR2B regulation. These findings could be of relevance to many neurodevelopmental disorders, as NRG1 and BDNF signaling pathways have been implicated in autism and schizophrenia.
Source: Epidemiologic Perspectives and Innovations - July 24, 2014 Category: Epidemiology Authors: Chirayu C PandyaAnilkumar PILLAI Source Type: research
