• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Characterization of beta2-microglobulin expression in different types of breast cancer
Background: Betaeta-2-microglobulin (beta2-M) has been demonstrated as a growth factor and signaling molecule in breast cancer and leukemia. The purpose of the study is to characterize beta2-M expression in molecular subtypes of breast cancer, thereby investigating the mechanism of beta2-M action in breast cancer. Methods: beta2-M and B-Cell Lymphoma/Leukemia 2 (Bcl-2) transcript expression levels in breast cancer tissue and the corresponding normal tissue were quantified using real-time PCR. The protein expression levels of beta2-M, estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor...
Source: Epidemiologic Perspectives and Innovations - October 7, 2014 Category: Epidemiology Authors: Kesheng LiHuifen DuXiaowen LianSuisheng YangDandan ChaiChunya WangRong YangXuezhong Chen Source Type: research

Inhibition of long non-coding RNA NEAT1 impairs myeloid differentiation in acute promyelocytic leukemia cells
Conclusions: Our results indicate that reduced expression of the nuclear long noncoding RNA NEAT1 may play a role in the myeloid differentiation of APL cells.
Source: Epidemiologic Perspectives and Innovations - September 23, 2014 Category: Epidemiology Authors: Chengwu ZengYan XuLing XuXibao YuJingjing ChengLijian YangShaohua ChenYangqiu Li Source Type: research