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Construction and identification of a model for HJURP gene defect expression in human embryo villus cells.
CONCLUSION: A lentiviral shRNA expression vector targeting the HJURP gene was successfully constructed and may effectively silence the target gene at a cellular level, which provides a experimental model for the influence of HJURP gene expressing inhibition on human embryo villus cells multiplication and chromosome segregation. PMID: 29949288 [PubMed - in process]
Source: Clinical and Experimental Obstetrics and Gynecology - June 30, 2018 Category: OBGYN Tags: Clin Exp Obstet Gynecol Source Type: research

Effect of Wnt/ β-catenin signal pathway on of matrix metalloproteinase-7 and vascular endothelial growth factor gene expressions in endometriosis.
CONCLUSION: Blocking of Wnt/β-catenin signal pathway caused the decrease of MMP-7 and VEGF expressions, in- dicating that Wnt/β-catenin signal pathway plays an important role in the adhesion, invasion, and metastasis of endometriosis tissues. PMID: 29734552 [PubMed]
Source: Clinical and Experimental Obstetrics and Gynecology - May 10, 2018 Category: OBGYN Tags: Clin Exp Obstet Gynecol Source Type: research

Effects of apelin on proliferation and apoptosis in rat ovarian granulosa cells.
CONCLUSION: Apelin can promote proliferation of GCs and inhibit apoptosis via PI3/Akt signaling pathway. PMID: 27328502 [PubMed - in process]
Source: Clinical and Experimental Obstetrics and Gynecology - June 23, 2016 Category: OBGYN Tags: Clin Exp Obstet Gynecol Source Type: research