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The Antiviral Role of Zinc and Metallothioneins in Hepatitis C Infection
This article is protected by copyright. All rights reserved.
Source: Journal of Viral Hepatitis - December 1, 2017 Category: Infectious Diseases Authors: Scott A Read, Grant Parnell, David Booth, Mark W Douglas, Jacob George, Golo Ahlenstiel Tags: Original Paper Source Type: research

Alpha ‐enolase regulates hepatitis B virus replication through suppression of the interferon signalling pathway
Summary Persistent chronic infection with hepatitis B virus (HBV) is a major risk factor for the development of HBV‐related diseases. The molecular mechanisms that underlie HBV infection and associated carcinogenesis are not fully understood. The aim of this study was to explore the role of ENO1 in HBV replication processes. Here, we examined ENO1 expression levels in HBV‐infected and non‐HBV‐infected liver tissues and cells by Western blot analysis, real‐time PCR and immunohistochemistry. In addition, HBsAg and HBeAg in the media of transfected HepG2.2.15 cells were detected using an electrochemical luminescence...
Source: Journal of Viral Hepatitis - November 20, 2017 Category: Infectious Diseases Authors: D. Xiang ‐Chun, Y. Xiao‐qing, Y. Ting‐Ting, L. Zhen‐Hui, L. Xiao‐Yan, L. Xia, H. Yan‐Chao, Y. Yi‐Xuan, M. Li‐Na Tags: ORIGINAL ARTICLE Source Type: research

ENO1 (alpha ‐enolase) Regulates HBV Replication through Suppression of the IFN Signaling Pathway
This article is protected by copyright. All rights reserved.
Source: Journal of Viral Hepatitis - October 27, 2017 Category: Infectious Diseases Authors: Ding Xiang ‐Chun, Yang Xiao‐qing, Yan Ting‐Ting, Lu Zhen‐Hui, Liu Xiao‐Yan, Luo Xia, Hu Yan‐Chao, Yang Yi‐Xuan, Ma Li‐Na Tags: Original Paper Source Type: research

Hepatitis B virus x protein induces autophagy via activating death‐associated protein kinase
In conclusion, HBX induces autophagy via activating DAPK in a pathway related to Beclin 1, but not JNK. This new finding should help us to understand the role of autophagy in HBX‐mediated pathogenesis and thus may provide targets for intervening HBX‐related disorders.
Source: Journal of Viral Hepatitis - November 4, 2013 Category: Infectious Diseases Authors: H.‐T Zhang, G. G. Chen, B.‐G. Hu, Z.‐Y. Zhang, J.‐P Yun, M.‐L. He, P. B. S. Lai Tags: Original Article Source Type: research