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p15(INK4b) regulates cell cycle signaling in hippocampal astrocytes of aged rats.
CONCLUSIONS: These observations suggest p15(INK4b) is expressed at a steady level in neonatal and adult rat hippocampal astrocytes with no effect on cell cycle regulation. Importantly, aged astrocyte cell cycle regulation was significantly affected by high expression levels of p15(INK4b) suggesting a role for p15(INK4b) in cell cycle regulation when it is expressed at high but not moderate or low levels in hippocampal astrocytes. PMID: 26526028 [PubMed - as supplied by publisher]
Source: Aging Clinical and Experimental Research - November 2, 2015 Category: Geriatrics Authors: Wang F, Zhang L Tags: Aging Clin Exp Res Source Type: research