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Lonp1 and Sig-1R contribute to the counteraction of ursolic acid against ochratoxin A-induced mitochondrial apoptosis
In conclusion, through mutual promotion between Lonp1 and Sig-1R, UA could effectively relieve OTA-induced apoptosis in vitro and break the vicious cycle between oxidative stress and ERS, which activated the mitochondrial apoptosis pathway.PMID:36587836 | DOI:10.1016/j.fct.2022.113592
Source: Food and Chemical Toxicology - January 1, 2023 Category: Food Science Authors: Qipeng Zhang Wenying Chen Boyang Zhang Yiwen Zhang Yuqing Xiao Yichen An Lingyun Han Huiqiong Deng Song Yao Hongwei Wang Xiao Li Shen Source Type: research