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Source: Mol Biol Cell
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Total 2 results found since Jan 2013.
MRI-Visible Nanovehicle for Efficient siRNA Delivery
Methods Mol Biol. 2021;2282:195-208. doi: 10.1007/978-1-0716-1298-9_13.ABSTRACTVisualizing siRNA delivery through medical imaging methods has drawn much attentions in recent gene therapy studies. Among them, iron oxide-based magnetic resonance imaging (MRI) is regarded as one of the most promising imaging modalities for its high spatial resolution as well as deep penetration and real-time properties. In this chapter, a detailed protocol of an amphiphilic superparamagnetic iron oxide (SPIO) nanovehicle-based siRNA delivery is described, mainly focusing on SPIO/siRNA complexes formation and characterization, in vitro and in ...
Source: Mol Biol Cell - April 30, 2021 Category: Molecular Biology Authors: Rongrong Jin Wencheng Zhu Gan Lin Gang Liu Hua Ai Source Type: research
