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Total 56 results found since Jan 2013.
Knockdown of TRIM66 in MDA-MB-468 triple negative breast cancer cell line suppresses proliferation and promotes apoptosis through EGFR signaling
Pol J Pathol. 2021;72(2):160-166. doi: 10.5114/pjp.2021.109518.ABSTRACTTriple negative breast cancer (TNBC) is one of the most common malignant tumors in women and the tripartite motif 66 (TRIM66) is closely associated with the behaviors of wide variety of cancer. Thus, in this study, we aimed to explore the effect of TRIM66 in MDA-MB-468 TNBC cell line. Western blot and RT-PCR assays were used to detect the expression level of TRIM66 in human normal mammary cells and human breast cancer cell lines. We silenced its expression in MDA-MB-468 cells by transient siRNA transfection to ascertain the function of TRIM66 in MDA-MB-...
Source: Polish Journal of Pathology - October 28, 2021 Category: Pathology Authors: Huayi Zhang Yaqin Zheng Yongmei Zhang Source Type: research
